4.6 Article

Autism and autistic traits in those who died by suicide in England

Journal

BRITISH JOURNAL OF PSYCHIATRY
Volume 221, Issue 5, Pages 683-691

Publisher

CAMBRIDGE UNIV PRESS
DOI: 10.1192/bjp.2022.21

Keywords

autism spectrum disorders; autistic traits; suicide; mortality; autism

Categories

Funding

  1. Autistica [7247]
  2. Economic and Social Research Council Future Research Leaders grant [ES/N000501/2]
  3. Coventry University
  4. Wellcome Trust [214322\Z\18\Z]
  5. Innovative Medicines Initiative 2 Joint Undertaking (JU) [777394]
  6. European Union
  7. EFPIA
  8. University of Nottingham
  9. AUTISM SPEAKS
  10. Autistica
  11. SFARI
  12. Autism Research Trust
  13. Templeton World Charitable Fund
  14. NIHR Cambridge Biomedical Research Centre
  15. National Institute for Health Research (NIHR) Collaboration for Leadership in Applied Health Research and Care East of England at Cambridgeshire and Peterborough NHS Foundation Trust

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This study found that elevated autistic traits are significantly over-represented in individuals who die by suicide. The characteristics of those who died, regardless of evidence of autism, are largely similar with a high number of multiple risk markers.
Background Autism and autistic traits are risk factors for suicidal behaviour. Aims To explore the prevalence of autism (diagnosed and undiagnosed) in those who died by suicide, and identify risk factors for suicide in this group. Method Stage 1: 372 coroners' inquest records, covering the period 1 January 2014 to 31 December 2017 from two regions of England, were analysed for evidence that the person who died had diagnosed autism or undiagnosed possible autism (elevated autistic traits), and identified risk markers. Stage 2: 29 follow-up interviews with the next of kin of those who died gathered further evidence of autism and autistic traits using validated autism screening and diagnostic tools. Results Stage 1: evidence of autism (10.8%) was significantly higher in those who died by suicide than the 1.1% prevalence expected in the UK general alive population (odds ratio (OR) = 11.08, 95% CI 3.92-31.31). Stage 2: 5 (17.2%) of the follow-up sample had evidence of autism identified from the coroners' records in stage 1. We identified evidence of undiagnosed possible autism in an additional 7 (24.1%) individuals, giving a total of 12 (41.4%); significantly higher than expected in the general alive population (1.1%) (OR = 19.76, 95% CI 2.36-165.84). Characteristics of those who died were largely similar regardless of evidence of autism, with groups experiencing a comparably high number of multiple risk markers before they died. Conclusions Elevated autistic traits are significantly over-represented in those who die by suicide.

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