Related references
Note: Only part of the references are listed.A multicenter, randomized phase III trial of hetrombopag: a novel thrombopoietin receptor agonist for the treatment of immune thrombocytopenia
Heng Mei et al.
JOURNAL OF HEMATOLOGY & ONCOLOGY (2021)
Preclinical Efficacy and Anti-Inflammatory Mechanisms of Action of the Bruton Tyrosine Kinase Inhibitor Rilzabrutinib for Immune-Mediated Disease
Claire L. Langrish et al.
JOURNAL OF IMMUNOLOGY (2021)
Engineered IgG1-Fc Molecules Define Valency Control of Cell Surface Fcγ Receptor Inhibition and Activation in Endosomes
Elizabeth M. Bailey et al.
FRONTIERS IN IMMUNOLOGY (2021)
Sutimlimab in Cold Agglutinin Disease
Alexander Roeth et al.
NEW ENGLAND JOURNAL OF MEDICINE (2021)
Dexamethasone plus oseltamivir versus dexamethasone in treatment-naive primary immune thrombocytopenia: a multicentre, randomised, open-label, phase 2 trial
Lu Sun et al.
Lancet Haematology (2021)
Hetrombopag: First Approval
Yahiya Y. Syed
DRUGS (2021)
Mycophenolate Mofetil for First-Line Treatment of Immune Thrombocytopenia
Charlotte A. Bradbury et al.
NEW ENGLAND JOURNAL OF MEDICINE (2021)
Sialylated immunoglobulin G: a promising diagnostic and therapeutic strategy for autoimmune diseases
Danqi Li et al.
THERANOSTICS (2021)
Phase 2 study of efgartigimod, a novel FcRn antagonist, in adult patients with primary immune thrombocytopenia
Adrian C. Newland et al.
AMERICAN JOURNAL OF HEMATOLOGY (2020)
Safety, tolerability, pharmacokinetics and pharmacodynamics of the anti-CD38 cytolytic antibody TAK-079 in healthy subjects
Eric R. Fedyk et al.
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY (2020)
Effect of postdose fasting duration on hetrombopag olamine pharmacokinetics and pharmacodynamics in healthy volunteers
Guoping Yang et al.
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY (2020)
Macrophage galactose lectin is critical for Kupffer cells to clear aged platelets
Carsten Deppermann et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2020)
Evaluating the effects of oseltamivir phosphate on platelet counts: a retrospective review
Hila Shaim et al.
PLATELETS (2020)
Immune Thrombocytopenia in Adults: Modern Approaches to Diagnosis and Treatment
Hanny Al-Samkari et al.
SEMINARS IN THROMBOSIS AND HEMOSTASIS (2020)
High-dose dexamethasone plus recombinant human thrombopoietin vs high-dose dexamethasone alone as frontline treatment for newly diagnosed adult primary immune thrombocytopenia: A prospective, multicenter, randomized trial
Yafei Yu et al.
AMERICAN JOURNAL OF HEMATOLOGY (2020)
Effect of Food on the Pharmacokinetic and Pharmacodynamic Profiles of Hetrombopag in Healthy Volunteers
Zhenlei Wang et al.
CLINICAL THERAPEUTICS (2020)
An update on the pathophysiology of immune thrombocytopenia
John W. Semple et al.
CURRENT OPINION IN HEMATOLOGY (2020)
Physical mechanisms of platelet formation
David Saintillan
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2020)
First-in-patient study of hetrombopag in patients with chronic idiopathic thrombocytopenic purpura
Zhenlei Wang et al.
JOURNAL OF THROMBOSIS AND HAEMOSTASIS (2020)
Phase 2 multiple-dose study of an FcRn inhibitor, rozanolixizumab, in patients with primary immune thrombocytopenia
Tadeusz Robak et al.
BLOOD ADVANCES (2020)
Romiplostim in adults with newly diagnosed or persistent immune thrombocytopenia
Maria L. Lozano et al.
EXPERT REVIEW OF HEMATOLOGY (2020)
Long-Term Safety and Efficacy of Sutimlimab in Patients with Chronic Immune Thrombocytopenia
Catherine M. Broome et al.
BLOOD (2020)
A modern reassessment of glycoprotein-specific direct platelet autoantibody testing in immune thrombocytopenia
Hanny Al-Samkari et al.
BLOOD ADVANCES (2020)
Serum complement levels in immune thrombocytopenia: Characterization and relation to clinical features
Abraham Z. Cheloff et al.
RESEARCH AND PRACTICE IN THROMBOSIS AND HAEMOSTASIS (2020)
Effects of ibrutinib on in vitro platelet aggregation in blood samples from healthy donors and donors with platelet dysfunction
Joi Ninomoto et al.
HEMATOLOGY (2020)
The solution structure of the human IgG2 subclass is distinct from those for human IgG1 and IgG4 providing an explanation for their discrete functions
Gar Kay Hui et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2019)
Hyper-Sialylated IgG M254, an Innovative Therapeutic Candidate, Evaluated in Healthy Volunteers and in Patients with Immune Thrombocytopenia Purpura: Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics
Santiago Arroyo et al.
BLOOD (2019)
A recombinant human IgG1 Fc multimer designed to mimic the active fraction of IVIG in autoimmunity
Xiaoyu Zhang et al.
JCI INSIGHT (2019)
Chronic immune thrombocytopenia in Denmark, Sweden and Norway: The Nordic Country Patient Registry for Romiplostim
Christian Fynbo Christiansen et al.
ECLINICALMEDICINE (2019)
American Society of Hematology 2019 guidelines for immune thrombocytopenia
Cindy Neunert et al.
BLOOD ADVANCES (2019)
Updated international consensus report on the investigation and management of primary immune thrombocytopenia
Drew Provan et al.
BLOOD ADVANCES (2019)
Bortezomib for Refractory Immune-Mediated Thrombocytopenia Purpura
Joan D. Beckman et al.
AMERICAN JOURNAL OF THERAPEUTICS (2018)
The development of Bruton's tyrosine kinase (BTK) inhibitors from 2012 to 2017: A mini-review
Chengyuan Liang et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2018)
In vivo depletion of serum IgG by an affibody molecule binding the neonatal Fc receptor
Johan Seijsing et al.
SCIENTIFIC REPORTS (2018)
Pharmacological characterization of hetrombopag, a novel orally active human thrombopoietin receptor agonist
Chengying Xie et al.
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2018)
Neonatal Fc receptor antagonist efgartigimod safely and sustainably reduces IgGs in humans
Peter Ulrichts et al.
JOURNAL OF CLINICAL INVESTIGATION (2018)
Proteasome Inhibition with Bortezomib Induces Apoptosis of Long-Lived Plasma Cells in Steroid-Resistant or Relapsed Immune Thrombocytopaenia
Guosheng Li et al.
THROMBOSIS AND HAEMOSTASIS (2018)
Required Immunoproteasome Subunit Inhibition Profile for Anti-Inflammatory Efficacy and Clinical Candidate KZR-616 ((2S,3R)-N-((S)-3-(Cyclopent-1-en-1-yl)-((R)-2-methyloxiran-2-yl)-1-oxopropan-2-yl)-3-hydroxy-3-(4-methoxyphenyl)-2-((S)-2-(2-morpholinoacetamido)propanamido)propenannide)
Henry W. B. Johnson et al.
JOURNAL OF MEDICINAL CHEMISTRY (2018)
A highly purified form of staphylococcal protein A alleviates murine immune thrombocytopenia (ITP)
Rick Kapur et al.
BRITISH JOURNAL OF HAEMATOLOGY (2018)
A Single Administration of the Cytolytic CD38 Antibody TAK-079 to Healthy Subjects: Tolerability, Pharmacokinetics and Pharmacodynamics
Eric Robert Fedyk et al.
BLOOD (2018)
Rituximab in immune thrombocytopenia: gender, age, and response as predictors of long-term response
Miriam Marangon et al.
EUROPEAN JOURNAL OF HAEMATOLOGY (2017)
Sialylation on O-glycans protects platelets from clearance by liver Kupffer cells
Yun Li et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)
Multivalent Fcγ-receptor engagement by a hexameric Fc-fusion protein triggers Fcγ-receptor internalisation and modulation of Fcγ-receptor functions
O. S. Qureshi et al.
SCIENTIFIC REPORTS (2017)
Safety, Pharmacokinetics and Pharmacodynamics of Hetrombopag Olamine, a Novel TPO-R Agonist, in Healthy Individuals
Li Zheng et al.
BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY (2017)
Daratumumab (anti-CD38) induces loss of CD38 on red blood cells
Harold C. Sullivan et al.
BLOOD (2017)
A fully recombinant human IgG1 Fc multimer (GL-2045) inhibits complement-mediated cytotoxicity and induces iC3b
Hua Zhou et al.
BLOOD ADVANCES (2017)
Remission and platelet responses with romiplostim in primary immune thrombocytopenia: final results from a phase 2 study
Adrian Newland et al.
BRITISH JOURNAL OF HAEMATOLOGY (2016)
Incidence and description of autoimmune cytopenias during treatment with ibrutinib for chronic lymphocytic leukemia
K. A. Rogers et al.
LEUKEMIA (2016)
Clinical efficacy of daratumumab monotherapy in patients with heavily pretreated relapsed or refractory multiple myeloma
Saad Z. Usmani et al.
BLOOD (2016)
Unexpected platelets elevation in a patient with idiopathic thrombocytopenia treated with oseltamivir for influenza infection
Pierre Bigot et al.
FUNDAMENTAL & CLINICAL PHARMACOLOGY (2016)
Remissions after long-term use of romiplostim for immune thrombocytopenia
Ariela L. Marshall et al.
HAEMATOLOGICA (2016)
Photobiomodulation in promoting wound healing: a review
Damien P. Kuffler
REGENERATIVE MEDICINE (2016)
Elucidating the interplay between IgG-Fc valency and FcγR activation for the design of immune complex inhibitors
Daniel F. Ortiz et al.
SCIENCE TRANSLATIONAL MEDICINE (2016)
Noninvasive low-level laser therapy for thrombocytopenia
Qi Zhang et al.
SCIENCE TRANSLATIONAL MEDICINE (2016)
Remissions after long-term use of romiplostim for immune thrombocytopenia
Ariela L. Marshall et al.
HAEMATOLOGICA (2016)
CD8+ T cells induce platelet clearance in the liver via platelet desialylation in immune thrombocytopenia
Jihua Qiu et al.
SCIENTIFIC REPORTS (2016)
Safety and Efficacy of PRTX-100, a Highly Purified Form of Staphylococcal Protein A, in Patients with Immune Thrombocytopenia (ITP)
James B. Bussel et al.
BLOOD (2016)
Staphylococcus aureus Infections: Epidemiology, Pathophysiology, Clinical Manifestations, and Management
Steven Y. C. Tong et al.
CLINICAL MICROBIOLOGY REVIEWS (2015)
Controlled tetra-Fc sialylation of IVIg results in a drug candidate with consistent enhanced anti-inflammatory activity
Nathaniel Washburn et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
Desialylation is a mechanism of Fc-independent platelet clearance and a therapeutic target in immune thrombocytopenia
June Li et al.
NATURE COMMUNICATIONS (2015)
New Insights into the Function of the Immunoproteasome in Immune and Nonimmune Cells
Hiroaki Kimura et al.
JOURNAL OF IMMUNOLOGY RESEARCH (2015)
Ibrutinib inhibits collagen-mediated but not ADP-mediated platelet aggregation
S. Kamel et al.
LEUKEMIA (2015)
The Ashwell-Morell receptor regulates hepatic thrombopoietin production via JAK2-STAT3 signaling
Renata Grozovsky et al.
NATURE MEDICINE (2015)
Mitoquinone restores platelet production in irradiation-induced thrombocytopenia
Haley Ramsey et al.
PLATELETS (2015)
Successful treatment with oseltamivir phosphate in a patient with chronic immune thrombocytopenia positive for anti-GPIb/IX autoantibody
Linlin Shao et al.
PLATELETS (2015)
Broad requirement for terminal sialic acid residues and Fc.RIIB for the preventive and therapeutic activity of intravenous immunoglobulins in vivo
Inessa Schwab et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2014)
Stress-induced hematopoietic failure in the absence of immediate early response gene X-1 (IEX-1, IER3)
Haley Ramsey et al.
HAEMATOLOGICA (2014)
Staphylococcus aureus infection induces protein A-mediated immune evasion in humans
Noel T. Pauli et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2014)
Advertisement Translation Revisited: Interdisciplinary Connections
Lu Shao
PROCEEDINGS OF INTERNATIONAL SYMPOSIUM ON GLOBALIZATION: CHALLENGES FOR TRANSLATORS AND INTERPRETERS (2014)
An engineered affibody molecule with pH-dependent binding to FcRn mediates extended circulatory half-life of a fusion protein
Johan Seijsing et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
The role of FcRn in antigen presentation
Kristi Baker et al.
FRONTIERS IN IMMUNOLOGY (2014)
Neonatal Fc receptors for IgG drive CD8+ T cell-mediated anti-cancer immunosurveillance at tolerogenic mucosal sites
Kristi Baker et al.
ONCOIMMUNOLOGY (2014)
PRTX-100 and Methotrexate in Patients With Active Rheumatoid Arthritis: A Phase Ib Randomized, Double-Blind, Placebo-Controlled, Dose-Escalation Study
Edward Bernton et al.
CLINICAL PHARMACOLOGY IN DRUG DEVELOPMENT (2014)
The Immunologic Functions of the Neonatal Fc Receptor for IgG
Timo Rath et al.
JOURNAL OF CLINICAL IMMUNOLOGY (2013)
B cell depletion in immune thrombocytopenia reveals splenic long-lived plasma cells
Matthieu Mahevas et al.
JOURNAL OF CLINICAL INVESTIGATION (2013)
Beneficial effect of a multimerized immunoglobulin Fc in an animal model of inflammatory neuropathy (experimental autoimmune neuritis)
Marzieh Niknami et al.
JOURNAL OF THE PERIPHERAL NERVOUS SYSTEM (2013)
CLEC4F Is an Inducible C-Type Lectin in F4/80-Positive Cells and Is Involved in Alpha-Galactosylceramide Presentation in Liver
Chih-Ya Yang et al.
PLOS ONE (2013)
Inducing host protection in pneumococcal sepsis by preactivation of the Ashwell-Morell receptor
Prabhjit K. Grewal et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Autoantibody-mediated complement activation on platelets is a common finding in patients with immune thrombocytopenic purpura (ITP)
Abderrahim Najaoui et al.
EUROPEAN JOURNAL OF HAEMATOLOGY (2012)
A novel and simple hollow-fiber assay for in vivo evaluation of nonpeptidyl thrombopoietin receptor agonists
Cheng-Ying Xie et al.
EXPERIMENTAL HEMATOLOGY (2012)
LED Phototherapy Improves Healing of Nipple Trauma: A Pilot Study
Maria Emilia de Abreu Chaves et al.
PHOTOMEDICINE AND LASER SURGERY (2012)
Platelet Kinetics in Idiopathic Thrombocytopenic Purpura Patients Treated with Thrombopoietin Receptor Agonists
Oliver Meyer et al.
TRANSFUSION MEDICINE AND HEMOTHERAPY (2012)
Fully recombinant IgG2a Fc multimers (stradomers) effectively treat collagen-induced arthritis and prevent idiopathic thrombocytopenic purpura in mice
Ajay Jain et al.
ARTHRITIS RESEARCH & THERAPY (2012)
Inferring reasons for the failure of Staphylococcus aureus vaccines in clinical trials
Fabio Bagnoli et al.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY (2012)
A murine model of severe immune thrombocytopenia is induced by antibody- and CD8+ T cell-mediated responses that are differentially sensitive to therapy
Leola Chow et al.
BLOOD (2010)
Pharmacokinetics of oseltamivir: an oral antiviral for the treatment and prophylaxis of influenza in diverse populations
Brian E. Davies
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY (2010)
Cross-species Binding Analyses of Mouse and Human Neonatal Fc Receptor Show Dramatic Differences in Immunoglobulin G and Albumin Binding
Jan Terje Andersen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Novel and unexpected clearance mechanisms for cold platelets
Viktoria Rumjantseva et al.
TRANSFUSION AND APHERESIS SCIENCE (2010)
Proteasomes in immune cells: more than peptide producers?
Marcus Groettrup et al.
NATURE REVIEWS IMMUNOLOGY (2010)
Of mice and men: an open-label pilot study for treatment of immune thrombocytopenic purpura by an inhibitor of Syk
Anna Podolanczuk et al.
BLOOD (2009)
Standardization of terminology, definitions and outcome criteria in immune thrombocytopenic purpura of adults and children: report from an international working group
Francesco Rodeghiero et al.
BLOOD (2009)
Epidemiology of immune thrombocytopenic purpura in the General Practice Research Database
W. Marieke Schoonen et al.
BRITISH JOURNAL OF HAEMATOLOGY (2009)
Dual roles for hepatic lectin receptors in the clearance of chilled platelets
Viktoria Rumjantseva et al.
NATURE MEDICINE (2009)
Anti-inflammatory actions of intravenous immunoglobulin
Falk Nimmerjahn et al.
ANNUAL REVIEW OF IMMUNOLOGY (2008)
Human IgG2 antibodies display disulfide-mediated structural isoforms
Jette Wypych et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Structural and functional characterization of disulfide isoforms of the human IgG2 subclass
Thomas M. Dillon et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
A mutation of human cytochrome c enhances the intrinsic apoptotic pathway but causes only thrombocytopenia
Ian M. Morison et al.
NATURE GENETICS (2008)
Complement evasion by human pathogens
John D. Lambris et al.
NATURE REVIEWS MICROBIOLOGY (2008)
Evolution and function of the ADP ribosyl cyclase/CD38 gene family in physiology and pathology
Fabio Malavasi et al.
PHYSIOLOGICAL REVIEWS (2008)
Reduction of IgG in nonhuman primates by a peptide antagonist of the neonatal Fc receptor FcRn
Adam R. Mezo et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Identification of a receptor required for the anti-inflammatory activity of IVIG
Robert M. Anthony et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Analysis of clinical presentations of Bruton Disease: A review of 20 years of accumulated data from pediatric patients at Severance Hospital
Jin-Kyong Chun et al.
YONSEI MEDICAL JOURNAL (2008)
The possible role of the ubiquitin proteasome system in the development of atherosclerosis in diabetes
Raffaele Marfella et al.
CARDIOVASCULAR DIABETOLOGY (2007)
Pharmacokinetic/pharmacodynamic modeling of IVIG effects in a murine model of immune thrombocytopenia
Rong Deng et al.
JOURNAL OF PHARMACEUTICAL SCIENCES (2007)
FcRn: the neonatal Fc receptor comes of age
Derry C. Roopenian et al.
NATURE REVIEWS IMMUNOLOGY (2007)
Anti-inflammatory activity of immunoglobulin G resulting from Fc sialylation
Yoshikatsu Kaneko et al.
SCIENCE (2006)
The conundrum of CDO function: host protection or disease promotion?
RK Mathur et al.
TRENDS IN PARASITOLOGY (2006)
Differential roles of microtubule assembly and sliding in proplatelet formation by megakaryocytes
SR Patel et al.
BLOOD (2005)
Mechanisms of organelle transport and capture along proplatelets during platelet production
JL Richardson et al.
BLOOD (2005)
The biogenesis of platelets from megakaryocyte propatelets
SR Patel et al.
JOURNAL OF CLINICAL INVESTIGATION (2005)
Engineering the Fc region of immunoglobulin G to modulate in vivo antibody levels
C Vaccaro et al.
NATURE BIOTECHNOLOGY (2005)
Suppression of in vitro megakaryocyte production by antiplatelet autoantibodies from adult patients with chronic ITP
R McMillan et al.
BLOOD (2004)
Effect of a single injection of humanized anti-CD154 monoclonal antibody on the platelet-specific autoimmune response in patients with immune thrombocytopenic purpura
M Kuwana et al.
BLOOD (2004)
Ultrastructural study shows morphologic features of apoptosis and para-apoptosis in megakaryocytes from patients with idiopathic thrombocytopenic purpura
EJ Houwerzijl et al.
BLOOD (2004)
T-cell-mediated cytotoxicity toward platelets in chronic idiopathic thrombocytopenic purpura
B Olsson et al.
NATURE MEDICINE (2003)
A phase 2 study of bortezomib in relapsed, refractory myeloma
PG Richardson et al.
NEW ENGLAND JOURNAL OF MEDICINE (2003)
Death by a B cell superantigen:: In vivo VH-targeted apoptotic supraclonal B cell deletion by a staphylococcal toxin
CS Goodyear et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2003)
Determination of the upper size limit for uptake and processing of ligands by the asialoglycoprotein receptor on hepatocytes in vitro and in vivo
PCN Rensen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Advances in immunology: Immunomodulation of autoimmune and inflammatory diseases with intravenous immune globulin.
MD Kazatchkine et al.
NEW ENGLAND JOURNAL OF MEDICINE (2001)
Therapeutic efficacy of intravenous immunoglobulin preparations depends on the immunoglobulin G dimers: studies in experimental immune thrombocytopenia
JL Teeling et al.
BLOOD (2001)
Development and characterization of novel erythropoiesis stimulating protein (NESP)
JC Egrie et al.
BRITISH JOURNAL OF CANCER (2001)
Anti-inflammatory activity of IVIG mediated through the inhibitory Fc receptor
A Samuelsson et al.
SCIENCE (2001)
Crystal structure of a Staphylococcus aureus protein A domain complexed with the Fab fragment of a human IgM antibody:: Structural basis for recognition of B-cell receptors and superantigen activity
M Graille et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
Share Paper
