Journal
BIOSENSORS & BIOELECTRONICS
Volume 197, Issue -, Pages -Publisher
ELSEVIER ADVANCED TECHNOLOGY
DOI: 10.1016/j.bios.2021.113777
Keywords
Flexible electronics; Graphene-based materials; Healthcare monitoring; Machine learning; Point-of-care testing
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Funding
- Fundamental Research Funds for the Central Universities [xzy022019014]
- National Key R&D Program of China [2018YFC1707700]
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This paper reviews the recent advances in the development and modification of graphene-based materials for fabricating advanced wearable sensors, summarizing the design guidelines, sensing mechanisms, applications and evolution. The challenges and future prospects in this field are also discussed.
Wearable sensors in healthcare monitoring have recently found widespread applications in biomedical fields for their non-or minimal-invasive, user-friendly and easy-accessible features. Sensing materials is one of the major challenges to achieve these superiorities of wearable sensors for healthcare monitoring, while graphene-based materials with many favorable properties have shown great efficiency in sensing various biochemical and biophysical signals. In this paper, we review state-of-the-art advances in the development and modification of graphene-based materials (i.e., graphene, graphene oxide and reduced graphene oxide) for fabricating advanced wearable sensors with 1D (fibers), 2D (films) and 3D (foams/aerogels/hydrogels) macroscopic structures. We summarize the structural design guidelines, sensing mechanisms, applications and evolution of the graphenebased materials as wearable sensors for healthcare monitoring of biophysical signals (e.g., mechanical, thermal and electrophysiological signals) and biochemical signals from various body fluids and exhaled gases. Finally, existing challenges and future prospects are presented in this area.
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