4.8 Article

Liquid metal-polymer conductor-based wireless, battery-free epidermal patch

Journal

BIOSENSORS & BIOELECTRONICS
Volume 197, Issue -, Pages -

Publisher

ELSEVIER ADVANCED TECHNOLOGY
DOI: 10.1016/j.bios.2021.113765

Keywords

Wearable sensor; Sweat sensor; Stretchable conductor; Wireless communication; Microfluidics

Funding

  1. National Key R&D Program of China [2018YFA0902600, 2017YFA0205901]
  2. National Natural Science Foundation of China [21535001, 81730051, 21761142006]
  3. ChineseAcademy of Sciences [QYZDJ-SSW-SLH039, 121D11KYSB20170026, XDA16020902]
  4. Guangdong Innovative and Entrepreneurial Research Team Program [2019ZT08Y191]
  5. Guangzhou Municipal Science and Technology Bu-reau [202002020085]
  6. Tencent Foundation through the XPLORER PRIZE
  7. Shenzhen Bay Laboratory [SZBL2019062801004]

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The wearable epidermal patch based on liquid metal-polymer conductor can seamlessly monitor biological signals in real-time. It is fabricated with good stretchability, repeatability, and biocompatibility, and achieves wireless signal communication and power supply through LMPC-based antenna and wire. The epidermal patch exhibits excellent analytical performance for sweat analysis of metabolites, electrolytes, and urea.
Wearable epidermal patch can seamlessly monitor biological signals in real-time. Here, we report a liquid metalpolymer conductor-based wireless epidermal patch. The epidermal patch is made of a new conductive material called liquid metal-polymer conductors (LMPC). LMPC is made by casting and peeling off polymers from patterned liquid metal particles. Our printable conductors present good stretchability, repeatability, and biocompatibility. We fabricate LMPC-based antenna and wire, which achieves wireless signal communication and power supply. To demonstrate the capability of our LMPC-based antenna and wire, we fabricate an epidermal patch to analyze metabolites, electrolytes, and urea in sweat. When a portable device is close to the epidermal sensor, the device can power and read the sensor through LMPC-based antenna. The epidermal patch exhibited good analytical performance for sweat analysis with a low limit of detection, fast response time, and multiplex detection capabilities. This epidermal patch opens the possibility for a broad range of non-invasive diagnostic tools that can be used for health monitoring in the general population.

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