The effective astaxanthin productivities of immobilized Haematococcus pluvialis with bacterial cellulose

Haematococcus pluvialis is traditionally cultivated in a suspension for astaxanthin production. This study presents the novel cultivation approach by immobilized H. pluvialis in bacterial cellulose (BC) produced from the symbiosis of Gluconacetobacter xylinus and H. pluvialis. It was observed that the immobilization itself was a regulator to increase the astaxanthin content. The key genes associated to astaxanthin synthesis, such as psy, lcy, bkt, chy, were significantly up-regulated after immobilization. BC immobilized gel can be utilized concurrently with different technologies to improve astaxanthin accumulation (e.g., amount of induction medium, area of biogel, et al). A small-scale screen panel photobioreactor was design to explore the application of the cultivation approach. Compared to suspended culture, the induction time was shortened from 7 days to 3 days. Astaxanthin productivity of red stage reached 343.2 mg.m(-2).d(-1). This was greater than that of many other cultivation systems.

Automated summary

Immobilizing Haematococcus pluvialis in bacterial cellulose can improve astaxanthin content by up-regulating key genes associated with its synthesis. This novel cultivation approach shows promising results in increasing astaxanthin productivity compared to traditional suspension cultures.