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Microalgal secondary metabolite productions as a component of biorefinery: A review

Journal

BIORESOURCE TECHNOLOGY
Volume 344, Issue -, Pages -

Publisher

ELSEVIER SCI LTD
DOI: 10.1016/j.biortech.2021.126206

Keywords

Microalgae; Primary metabolites; Secondary metabolites; Co-production & co-extraction; Metabolites induction

Funding

  1. Commercializations Promotion Agency for R&D Outcomes (COMPA) - Korea gov-ernment (MSIT) [2021B300]
  2. Korea Environment Industry & Technology Institute (KEITI) - Korea Ministry of Environment (MOE) [2021003280004, 2021003240004]
  3. Korea Basic Science Institute (KBSI) [C070300]
  4. Science & Technology Job Promotion Agency, Republic of Korea [2021B300] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)

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There is a growing interest in utilizing microalgae for industrial purposes due to concerns about petroleum depletion and sustainable energy sources. Despite the advantages of high biomass productivity and short culture periods, barriers such as high unit price need to be addressed. Co-producing primary and secondary metabolites from microalgae is essential, with induction methods available to promote the biosynthesis of secondary metabolites for industrial applications.
The interest in developing microalgae for industrial use has been increasing because of concerns about the depletion of petroleum resources and securing sustainable energy sources. Microalgae have high biomass productivity and short culture periods. However, despite these advantages, various barriers need to be overcome for industrial applications. Microalgal cultivation has a high unit price, thus rendering industrial application difficult. It is indispensably necessary to co-produce their primary and secondary metabolites to compensate for these shortcomings. In this regard, this article reviews the following aspects, (1) co-production of primary and secondary metabolites in microalgae, (2) induction methods for the promotion of the biosynthesis of secondary metabolites, and (3) perspectives on the co-production and co-extraction of primary and secondary metabolites. This paper presents various approaches for producing useful metabolites from microalgae and suggests strategies that can be utilized for the co-production of primary and secondary metabolites.

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