Related references
Note: Only part of the references are listed.Discovery of highly potent and selective influenza virus neuraminidase inhibitors targeting 150-cavity
Ruifang Jia et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2021)
Design, synthesis, biological evaluation and molecular docking studies of new chalcone derivatives containing diaryl ether moiety as potential anticancer agents and tubulin polymerization inhibitors
Guangcheng Wang et al.
BIOORGANIC CHEMISTRY (2020)
Pemafibrate, a New Selective PPARα Modulator: Drug Concept and Its Clinical Applications for Dyslipidemia and Metabolic Diseases
Shizuya Yamashita et al.
CURRENT ATHEROSCLEROSIS REPORTS (2020)
Recent developments of chalcones as potential antibacterial agents in medicinal chemistry
Wenjia Dan et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2020)
The relationship between atherogenic index of plasma and no-reflow in patients with acute ST-segment elevation myocardial infarction who underwent primary percutaneous coronary intervention
Muhammed Suleymanoglu et al.
INTERNATIONAL JOURNAL OF CARDIOVASCULAR IMAGING (2020)
Evolution of a 4-Benzyloxy-benzylamino Chemotype to Provide Efficacious, Potent, and Isoform Selective PPARα Agonists as Leads for Retinal Disorders
Xiaozheng Dou et al.
JOURNAL OF MEDICINAL CHEMISTRY (2020)
Pemafibrate, a PPAR alpha agonist, attenuates neointima formation after vascular injury in mice fed normal chow and a high-fat diet
Tsuyoshi Horikawa et al.
HELIYON (2020)
Visible light photoredox catalyzed deprotection of 1,3-oxathiolanes
Mingyang Yang et al.
ORGANIC & BIOMOLECULAR CHEMISTRY (2020)
Novel chalcone and flavone derivatives as selective and dual inhibitors of the transport proteins ABCB1 and ABCG2
Katja Silbermann et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2019)
Novel Phenyldiazenyl Fibrate Analogues as PPAR α/γ/δ Pan-Agonists for the Amelioration of Metabolic Syndrome
Letizia Giampietro et al.
ACS MEDICINAL CHEMISTRY LETTERS (2019)
Effect of edible clay (takere) suspension on serum lipid profiles and atherogenic indices of normal Wistar rats
Catherine C. Ikewuchi et al.
FOOD SCIENCE & NUTRITION (2019)
Development of Fibrates as Important Scaffolds in Medicinal Chemistry
Letizia Giampietro et al.
CHEMMEDCHEM (2019)
Assessment of hypolipidemic, anti-inflammatory and antioxidant properties of medicinal plant Erica multiflora in triton WR-1339-induced hyperlipidemia and liver function repair in rats: A comparison with fenofibrate
Rihab Khlifi et al.
REGULATORY TOXICOLOGY AND PHARMACOLOGY (2019)
Effect of Propolis on Diet-Induced Hyperlipidemia and Atherogenic Indices in Mice
Nada Orsolic et al.
ANTIOXIDANTS (2019)
Fenofibrate decreases plasma ceramide in type 2 diabetes patients: A novel marker of CVD?
M. Croyal et al.
DIABETES & METABOLISM (2018)
Protective effect of fenofibrate against ischemia-/reperfusion-induced cardiac arrhythmias in isolated rat hearts
Ishfaq A. Bukhari et al.
FUNDAMENTAL & CLINICAL PHARMACOLOGY (2018)
Discovery of novel human inosine 5′-monophosphate dehydrogenase 2 (hIMPDH2) inhibitors as potential anticancer agents
Chetan P. Shah et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2018)
Identification of the First PPARα/γ Dual Agonist Able To Bind to Canonical and Alternative Sites of PPARγ and To Inhibit Its Cdk5-Mediated Phosphorylation
Antonio Laghezza et al.
JOURNAL OF MEDICINAL CHEMISTRY (2018)
Pharmacological evaluation of Convolvulus pluricaulis as hypolipidaemic agent in Triton WR-1339-induced hyperlipidaemia in rats
Gaurav Garg et al.
JOURNAL OF PHARMACY AND PHARMACOLOGY (2018)
Effect of lemongrass water extract supplementation on atherogenic index and antioxidant status in rats
Nuntiya Somparn et al.
ACTA PHARMACEUTICA (2018)
A novel structural class of coumarin-chalcone fibrates as PPARα/γ agonists with potent antioxidant activities: Design, synthesis, biological evaluation and molecular docking studies
Handong Niu et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2017)
Pemafibrate (K-877), a novel selective peroxisome proliferator-activated receptor alpha modulator for management of atherogenic dyslipidaemia
Jean-Charles Fruchart
CARDIOVASCULAR DIABETOLOGY (2017)
Therapeutic potential of chalcones as cardiovascular agents
Debarshi Kar Mahapatra et al.
LIFE SCIENCES (2016)
Zerumbone, a Bioactive Sesquiterpene, Ameliorates Diabetes-Induced Retinal Microvascular Damage through Inhibition of Phospho-p38 Mitogen-Activated Protein Kinase and Nuclear Factor-κB Pathways
Wayne Young Liu et al.
MOLECULES (2016)
Assessment of bioactive metabolites and hypolipidemic effect of polyphenolic-rich red cabbage extract
Alice Buss Cruz et al.
PHARMACEUTICAL BIOLOGY (2016)
Synthesis and evaluation of new indole-based chalcones as potential antiinflammatory agents
Ahmet Ozdemir et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2015)
Early investigational drugs targeting PPAR-α for the treatment of metabolic disease
Zhong-Min Liu et al.
EXPERT OPINION ON INVESTIGATIONAL DRUGS (2015)
Molecular mechanism of PPARα action and its impact on lipid metabolism, inflammation and fibrosis in non-alcoholic fatty liver disease
Michal Pawlak et al.
JOURNAL OF HEPATOLOGY (2015)
Atherogenic Dyslipidemia and Cardiovascular Risk Factors in Obese Children
Ebe D'Adamo et al.
INTERNATIONAL JOURNAL OF ENDOCRINOLOGY (2015)
PPARα agonists based on stilbene and its bioisosteres: biological evaluation and docking studies
Barbara De Filippis et al.
MEDCHEMCOMM (2015)
PPAR alpha Agonist Fenofibrate Ameliorates Learning and Memory Deficits in Rats Following Global Cerebral Ischemia
Ai-Guo Xuan et al.
MOLECULAR NEUROBIOLOGY (2015)
Design and synthesis of certain substituted cycloalkanecarboxamides structurally related to safinamide with anticonvulsant potential
Mohamed N. Aboul-Enein et al.
RESEARCH ON CHEMICAL INTERMEDIATES (2015)
Synthesis, biological activity and structure-activity relationships of new benzoic acid-based protein tyrosine phosphatase inhibitors endowed with insulinomimetic effects in mouse C2C12 skeletal muscle cells
Rosaria Ottana et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2014)
Design and synthesis of novel indole-chalcone fibrates as lipid lowering agents
Koneni V. Sashidhara et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2014)
Antihypercholesterolemic and Antioxidative Potential of an Extract of the Plant, Piper betle, and Its Active Constituent, Eugenol, in Triton WR-1339-Induced Hypercholesterolemia in Experimental Rats
Karuppasamy Venkadeswaran et al.
EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE (2014)
Hypolipidemic action of chrysin on Triton WR-1339-induced hyperlipidemia in female C57BL/6 mice
Micheli Stefani Zarzecki et al.
TOXICOLOGY REPORTS (2014)
Dyslipidemia in Obesity: Mechanisms and Potential Targets
Boudewijn Klop et al.
NUTRIENTS (2013)
Synthesis of chalcone derivatives as potential anti-diabetic agents
Chi-Ting Hsieh et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2012)
Synthesis and structure-activity relationships of fibrate-based analogues inside PPARs
Letizia Giampietro et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2012)
Dystroglycan is associated to the disulfide isomerase ERp57
Francesca Sciandra et al.
EXPERIMENTAL CELL RESEARCH (2012)
Novel phenoxyalkylcarboxylic acid derivatives as hypolipidaemic agents
Wei Li et al.
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY (2012)
Targeting Peroxisome Proliferator-Activated Receptors (PPARs): Development of Modulators
Celine Pirat et al.
JOURNAL OF MEDICINAL CHEMISTRY (2012)
Caffeoylquinic acid-rich extract from chicory seeds improves glycemia, atherogenic index, and antioxidant status in rats
Adam Jurgonski et al.
NUTRITION (2012)
Synthesis and antidyslipidemic activity of chalcone fibrates
Poonam Shukla et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2011)
Mitochondrial Carnitine Palmitoyltransferase 1a (CPT1a) Is Part of an Outer Membrane Fatty Acid Transfer Complex
Kwangwon Lee et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Fenofibrate Treatment Enhances Antioxidant Status and Attenuates Endothelial Dysfunction in Streptozotocin-Induced Diabetic Rats
Murat Olukman et al.
EXPERIMENTAL DIABETES RESEARCH (2010)
Antifungal activity of chalcones: A mechanistic study using various yeast strains
K. L. Lahtchev et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2008)
Substituted 2-[(4-aminomethyl)phenoxy]-2-methylpropionic acid PPARα agonists.: 1.: Discovery of a novel series of potent HDLc raising agents
Michael L. Sierra et al.
JOURNAL OF MEDICINAL CHEMISTRY (2007)
Role of oxidative modifications in atherosclerosis
R Stocker et al.
PHYSIOLOGICAL REVIEWS (2004)
Lipid-lowering therapy with fluvastatin inhibits oxidative modification of low density lipoprotein and improves vascular endothelial function in hypercholesterolemic patients
T Inoue et al.
ATHEROSCLEROSIS (2002)
Effects of fibrates on serum metabolic parameters
M Elisaf
CURRENT MEDICAL RESEARCH AND OPINION (2002)
Differential gene regulation in human versus rodent hepatocytes by peroxisome proliferator-activated receptor (PPAR) α -: PPARα fails to induce peroxisome proliferation-associated genes in human cells independently of the level of receptor expression
JW Lawrence et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Method for the measurement of antioxidant activity in human fluids
D Koracevic et al.
JOURNAL OF CLINICAL PATHOLOGY (2001)
Hypocholesterolemic and hypolipidemic activity of some novel morpholine derivatives with antioxidant activity
MC Chrysselis et al.
JOURNAL OF MEDICINAL CHEMISTRY (2000)
Asymmetry in the PPAR gamma/RXR alpha crystal structure reveals the molecular basis of heterodimerization among nuclear receptors
RT Gampe et al.
MOLECULAR CELL (2000)
Share Paper
