4.8 Article

Exosomes derived from immunogenically dying tumor cells as a versatile tool for vaccination against pancreatic cancer

Related references

Note: Only part of the references are listed.
Article Engineering, Biomedical

Pancreatic cancer-targeting exosomes for enhancing immunotherapy and reprogramming tumor microenvironment

Wenxi Zhou et al.

Summary: The study demonstrates a dual delivery biosystem based on exosomes for enhancing PDAC immunotherapy and reversing tumor immunosuppression. By disrupting the galectin-9/dectin 1 axis, the system can improve drug accumulation in the tumor site and elicit anti-tumor immune response.

BIOMATERIALS (2021)

Review Immunology

Dendritic cells in cancer immunology and immunotherapy

Stefanie K. Wculek et al.

NATURE REVIEWS IMMUNOLOGY (2020)

Article Cell Biology

Anchor peptide captures, targets, and loads exosomes of diverse origins for diagnostics and therapy

Xianjun Gao et al.

SCIENCE TRANSLATIONAL MEDICINE (2018)

Article Chemistry, Multidisciplinary

Immunogenic Cell Death Amplified by Co-localized Adjuvant Delivery for Cancer Immunotherapy

Yuchen Fan et al.

NANO LETTERS (2017)

Article Multidisciplinary Sciences

Exosomes facilitate therapeutic targeting of oncogenic KRAS in pancreatic cancer

Sushrut Kamerkar et al.

NATURE (2017)

Review Pharmacology & Pharmacy

Exploiting lymphatic vessels for immunomodulation: Rationale, opportunities, and challenges

Katharina Maisel et al.

ADVANCED DRUG DELIVERY REVIEWS (2017)

Article Nanoscience & Nanotechnology

Development of exosome-encapsulated paclitaxel to overcome MDR in cancer cells

Myung Soo Kim et al.

NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE (2016)

Article Multidisciplinary Sciences

Lymphatic transport of exosomes as a rapid route of information dissemination to the lymph node

Swetha Srinivasan et al.

SCIENTIFIC REPORTS (2016)

Article Oncology

Immune Checkpoint Blockade: A Common Denominator Approach to Cancer Therapy

Suzanne L. Topalian et al.

CANCER CELL (2015)

Review Immunology

Exosomes as nanocarriers for immunotherapy of cancer and inflammatory diseases

Thanh-Huyen Tran et al.

CLINICAL IMMUNOLOGY (2015)

Article Oncology

The Evolving Role of Immune Checkpoint Inhibitors in Cancer Treatment

Gregory K. Pennock et al.

ONCOLOGIST (2015)

Article Chemistry, Multidisciplinary

Dynamic Biodistribution of Extracellular Vesicles in Vivo Using a Multimodal Imaging Reporter

Charles P. Lai et al.

ACS NANO (2014)

Review Oncology

Two immune faces of pancreatic adenocarcinoma: possible implication for immunotherapy

Alexandr V. Bazhin et al.

CANCER IMMUNOLOGY IMMUNOTHERAPY (2014)

Article Immunology

Dendritic Cell-Derived Exosomes as Immunotherapies in the Fight against Cancer

Jonathan M. Pitt et al.

JOURNAL OF IMMUNOLOGY (2014)

Article Multidisciplinary Sciences

Structure-based programming of lymph-node targeting in molecular vaccines

Haipeng Liu et al.

NATURE (2014)

Article Multidisciplinary Sciences

PD-1 blockade induces responses by inhibiting adaptive immune resistance

Paul C. Tumeh et al.

NATURE (2014)

Article Medicine, General & Internal

Sodium and Cardiovascular Disease

NEW ENGLAND JOURNAL OF MEDICINE (2014)

Article Gastroenterology & Hepatology

Pancreatic cancer stroma: understanding biology leads to new therapeutic strategies

Agnieszka Anna Rucki et al.

WORLD JOURNAL OF GASTROENTEROLOGY (2014)

Review Immunology

Inflammatory networks and immune surveillance of pancreatic carcinoma

Robert H. Vonderheide et al.

CURRENT OPINION IN IMMUNOLOGY (2013)

Review Gastroenterology & Hepatology

The Epidemiology of Pancreatitis and Pancreatic Cancer

Dhiraj Yadav et al.

GASTROENTEROLOGY (2013)

Article Multidisciplinary Sciences

Anti-CCR4 mAb selectively depletes effector-type FoxP3+CD4+ regulatory T cells, evoking antitumor immune responses in humans

Daisuke Sugiyama et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)

Article Biochemistry & Molecular Biology

T-cell Receptor-optimized Peptide Skewing of the T-cell Repertoire Can Enhance Antigen Targeting

Julia Ekeruche-Makinde et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2012)

Review Immunology

Cross-presentation by dendritic cells

Olivier P. Joffre et al.

NATURE REVIEWS IMMUNOLOGY (2012)

Article Biotechnology & Applied Microbiology

Chemotherapy Delivered After Viral Immunogene Therapy Augments Antitumor Efficacy Via Multiple Immune-mediated Mechanisms

Zvi G. Fridlender et al.

MOLECULAR THERAPY (2010)

Review Multidisciplinary Sciences

Taking dendritic cells into medicine

Ralph M. Steinman et al.

NATURE (2007)

Article Biochemistry & Molecular Biology

Toll-like receptor 4-dependent contribution of the immune system to anticancer chemotherapy and radiotherapy

Lionel Apetoh et al.

NATURE MEDICINE (2007)

Article Multidisciplinary Sciences

Regulation of spontaneous intestinal tumorigenesis through the adaptor protein MyD88

Seth Rakoff-Nahoum et al.

SCIENCE (2007)

Article Biochemistry & Molecular Biology

Calreticulin exposure dictates the immunogenicity of cancer cell death

Michel Obeid et al.

NATURE MEDICINE (2007)

Review Immunology

Dendritic cells as therapeutic vaccines against cancer

J Banchereau et al.

NATURE REVIEWS IMMUNOLOGY (2005)

Article Biochemistry & Molecular Biology

Tumor-derived exosomes are a source of shared tumor rejection antigens for CTL cross-priming

J Wolfers et al.

NATURE MEDICINE (2001)