4.7 Article

Synthetic Sugar-Only Polymers with Double-Shoulder Task: Bioactivity and Imaging

Journal

BIOMACROMOLECULES
Volume 23, Issue 3, Pages 1075-1082

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/acs.biomac.1c01409

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Funding

  1. National Natural Science Foundation of China [21774084, 21935008]
  2. Priority Academic Program Development (PAPD) of Jiangsu Higher Education Institutions

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The search for novel fluorescent materials has attracted the attention of many researchers. In recent years, nonconventional fluorescence emitters have been developed as promising bioimaging candidates due to their enhanced biodegradability and relatively low cost, and their luminescent mechanism is similar to clustering-triggered emission (CTE). Our contribution involves the preparation of a series of glycopolymers with designed components using nonaromatic sugar as a monomer through sunlight-induced reversible addition fragmentation chain transfer polymerization, which can be utilized in bioimaging fields due to their bioactivity and CTE capacity.
The search for novel fluorescent materials has attracted the attention of many researchers. Numerous bioimaging materials based on the aggregation-induced emission (AIE) units have been surging and could be employed in wide areas during the past two decades. In recent few years, the appearance of nonconventional fluorescence emitters without aromatic conjugated structures provides another bioimaging candidate which has the advantage of enhanced biodegradability and relatively low cost, and their luminescent mechanism can be explained by clustering-triggered emission (CTE) like AIE. In our contribution, we utilize nonaromatic sugar as a monomer to prepare a series of glycopolymers with designed components through sunlight-induced reversible addition fragmentation chain transfer polymerization; these glycopolymers can be employed in bioimaging fields due to the bioactivity coming from sugar and CTE capacity.

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