Journal
BIOINFORMATICS
Volume 37, Issue 23, Pages 4556-4558Publisher
OXFORD UNIV PRESS
DOI: 10.1093/bioinformatics/btab688
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Funding
- Agropolis Fondation's 'GenomeHarvest' project [1504-006]
- CIFRE doctoral [2018/1475]
- Syngenta
- CGIAR Research Program, Roots, Tubers and Bananas
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Pangenomics has evolved to study all sequences available, with linear representations being a suitable option for user-friendliness. Panache is a tool for visualizing gene-based and sequence-based pangenomes, using a linear layout similar to genome browsers.
Motivation: Pangenomics evolved since its first applications on bacteria, extending from the study of genes for a given population to the study of all of its sequences available. While multiple methods are being developed to construct pangenomes in eukaryotic species there is still a gap for efficient and user-friendly visualization tools. Emerging graph representations come with their own challenges, and linearity remains a suitable option for user-friendliness. Results: We introduce Panache, a tool for the visualization and exploration of linear representations of gene-based and sequence-based pangenomes. It uses a layout similar to genome browsers to display presence absence variations and additional tracks along a linear axis with a pangenomics perspective.
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