Journal
BIOINFORMATICS
Volume 38, Issue 5, Pages 1463-1464Publisher
OXFORD UNIV PRESS
DOI: 10.1093/bioinformatics/btab819
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Funding
- National Council for Scientific and Technological Development (CNPq) [161552/2019-6]
- Fundacao Araucaria (FA) [NAPI Bioinformatica]
- CNPq [161552/2019-6, 304388/2018-1, 308258/2018-5]
- Coordination for the Improvement of Higher Education Personnel (CAPES)
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This study presents TreeAndLeaf, an R/Bioconductor package that implements a hybrid layout strategy for representing tree diagrams with a focus on the leaves. The package allows projection of multiple layers of information onto a graph-tree diagram.
Motivation: Dendrogram is a classical diagram for visualizing binary trees. Although efficient to represent hierarchical relations, it provides limited space for displaying information on the leaf elements, especially for large trees. Results: Here, we present TreeAndLeaf, an R/Bioconductor package that implements a hybrid layout strategy to represent tree diagrams with focus on the leaves. The TreeAndLeaf package combines force-directed graph and tree layout algorithms using a single visualization system, allowing projection of multiple layers of information onto a graph-tree diagram. The Supplementary Information Information provides two case studies that use breast cancer data from epidemiological and experimental studies.
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