Thermometer: a webserver to predict protein thermal stability

Motivation: Thermal properties of proteins are of great importance for a number of theoretical and practical implications. Predicting the thermal stability of a protein is a difficult and still scarcely addressed task. Results: Here, we introduce Thermometer, a webserver to assess the thermal stability of a protein using structural information. Thermometer is implemented as a publicly available, user-friendly interface. Availability and implementation: Our server can be found at the following link (all major browser supported): http://service.tartaglialab.com/new_submission/thermometer_file. Contact: edoardo.milanetti@uniroma1.it or gian.tartaglia@iit.it Supplementary information: Supplementary data are available at Bioinformatics online.

Automated summary

In this study, a webserver called Thermometer was developed to assess the thermal stability of proteins using structural information. The server is publicly available and has a user-friendly interface.