Related references
Note: Only part of the references are listed.Evaluating the current status of protein kinase C (PKC)-protein kinase D (PKD) signalling axis as a novel therapeutic target in ovarian cancer
Komal Tyagi et al.
BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER (2021)
Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries
Hyuna Sung et al.
CA-A CANCER JOURNAL FOR CLINICIANS (2021)
Proteogenomic and metabolomic characterization of human glioblastoma
Liang-Bo Wang et al.
CANCER CELL (2021)
Copy Number Variation and Rearrangements Assessment in Cancer: Comparison of Droplet Digital PCR with the Current Approaches
Vincenza Ylenia Cusenza et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)
PD-L1 recruits phospholipase C and enhances tumorigenicity of lung tumors harboring mutant forms of EGFR
Soma Ghosh et al.
CELL REPORTS (2021)
Frequent and Persistent PLCG1 Mutations in Sezary Cells Directly Enhance PLCγ1 Activity and Stimulate NFκB, AP-1, and NFAT Signaling
Varsha M. Patel et al.
JOURNAL OF INVESTIGATIVE DERMATOLOGY (2020)
The phospholipase C inhibitor U73122 is a potent agonist of the polymodal transient receptor potential ankyrin type 1 (TRPA1) receptor channel
Cristian Neacsu et al.
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY (2020)
Brain Metastasis organotropism
Arseniy E. Yuzhalin et al.
COLD SPRING HARBOR PERSPECTIVES IN MEDICINE (2020)
Genomic landscape of young ATLL patients identifies frequent targetable CD28 fusions
Noriaki Yoshida et al.
BLOOD (2020)
Primary Cutaneous CD4+ Small/Medium T-Cell Lymphoproliferative Disorders
Fanny Beltzung et al.
AMERICAN JOURNAL OF SURGICAL PATHOLOGY (2020)
p120-catenin suppresses proliferation and tumor growth of oral squamous cell carcinoma via inhibiting nuclear phospholipase C-γ1 signaling
Lusha Li et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2020)
Metastases to the central nervous system: Molecular basis and clinical considerations
Pitchaya Wanleenuwat et al.
JOURNAL OF THE NEUROLOGICAL SCIENCES (2020)
Phosphorylation of PLCγ1 by EphA2 Receptor Tyrosine Kinase Promotes Tumor Growth in Lung Cancer
Wenqiang Song et al.
MOLECULAR CANCER RESEARCH (2020)
FGFR1 Is Critical for RBL2 Loss-Driven Tumor Development and Requires PLCG1 Activation for Continued Growth of Small Cell Lung Cancer
Kee-Beom Kim et al.
CANCER RESEARCH (2020)
PLCγ1 suppression promotes the adaptation of KRAS-mutant lung adenocarcinomas to hypoxia
Maria Saliakoura et al.
NATURE CELL BIOLOGY (2020)
Somatic mutation distributions in cancer genomes vary with three-dimensional chromatin structure
Kadir C. Akdemir et al.
NATURE GENETICS (2020)
Phosphoinositide specific phospholipase Cγ1 inhibition-driven autophagy caused cell death in human lung adenocarcinoma A549 cells in vivo and in vitro
Xiaohong Lu et al.
INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES (2020)
Candidate susceptibility variants in angioimmunoblastic T-cell lymphoma
Iikki Donner et al.
FAMILIAL CANCER (2019)
Causes, consequences, and therapy of tumors acidosis
Smitha R. Pillai et al.
CANCER AND METASTASIS REVIEWS (2019)
miR-34a: a new player in the regulation of T cell function by modulation of NF-κB signaling
Martin Hart et al.
CELL DEATH & DISEASE (2019)
c-Cbl: An Important Regulator and a Target in Angiogenesis and Tumorigenesis
Chimera L. Lyle et al.
CELLS (2019)
PLC-gamma-1 phosphorylation status is prognostic of metastatic risk in patients with early-stage Luminal-A and -B breast cancer subtypes
Rossano Lattanzio et al.
BMC CANCER (2019)
Investigation of Phospholipase Cγ1 Interaction with SLP76 Using Molecular Modeling Methods for Identifying Novel Inhibitors
Neha Tripathi et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)
Role of Phytochemicals in Cancer Prevention
Alok Ranjan et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)
miR-222 represses expression of zipcode binding protein-1 and phospholipase C-γ1 in intestinal epithelial cells
Li-Ping Jiang et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2019)
Oncogenic role of phospholipase C-γ1 in progression of hepatocellular carcinoma
Wenqing Tang et al.
HEPATOLOGY RESEARCH (2019)
Structural basis for the activation of PLC-γ isozymes by phosphorylation and cancerassociated mutations
Nicole Hajicek et al.
ELIFE (2019)
Epidermal growth factor receptor overexpression and outcomes in early breast cancer: A systematic review and a meta-analysis
Galileo A. Gonzalez-Conchas et al.
CANCER TREATMENT REVIEWS (2018)
HSP70/HSP90-Organizing Protein Contributes to Gastric Cancer Progression in an Autocrine Fashion and Predicts Poor Survival in Gastric Cancer
Ertao Zhai et al.
CELLULAR PHYSIOLOGY AND BIOCHEMISTRY (2018)
Protein Tyrosine Phosphatase Receptor Type G (PTPRG) Controls Fibroblast Growth Factor Receptor (FGFR) 1 Activity and Influences Sensitivity to FGFR Kinase Inhibitors
Michal Kostas et al.
MOLECULAR & CELLULAR PROTEOMICS (2018)
Netrin-1/DCC-mediated PLC gamma 1 activation is required for axon guidance and brain structure development
Du-Seock Kang et al.
EMBO REPORTS (2018)
Kinomic profiling of glioblastoma cells reveals PLCG1 as a target in restricted glucose
Kiera Walker et al.
BIOMARKER RESEARCH (2018)
The role of phospholipase C gamma 1 in breast cancer and its clinical significance
Aikaterini Emmanouilidi et al.
FUTURE ONCOLOGY (2017)
UCP2 upregulation promotes PLC-1 signaling during skin cell transformation
Annapoorna Sreedhar et al.
MOLECULAR CARCINOGENESIS (2017)
Forebrain-specific ablation of phospholipase Cγ1 causes manic-like behavior
Y. R. Yang et al.
MOLECULAR PSYCHIATRY (2017)
MicroRNA therapeutics: towards a new era for the management of cancer and other diseases
Rajesha Rupaimoole et al.
NATURE REVIEWS DRUG DISCOVERY (2017)
Strategies to Target Glucose Metabolism in Tumor Microenvironment on Cancer by Flavonoids
Gang Wang et al.
NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL (2017)
Expression of phospholipase C isozymes in human breast cancer and their clinical significance
Shuo Cai et al.
ONCOLOGY REPORTS (2017)
Autocrine VEGF signaling promotes cell proliferation through a PLC-dependent pathway and modulates Apatinib treatment efficacy in gastric cancer
Yi Lin et al.
ONCOTARGET (2017)
Angioimmunoblastic T cell lymphoma: novel molecular insights by mutation profiling
Ming Wang et al.
Oncotarget (2017)
Hepatocyte Growth Factor, a Key Tumor-Promoting Factor in the Tumor Microenvironment
Benjamin Yaw Owusu et al.
CANCERS (2017)
Genetic alterations in adult T-cell leukemia/lymphoma
Yasunori Kogure et al.
CANCER SCIENCE (2017)
Grb2 depletion under non-stimulated conditions inhibits PTEN, promotes Akt-induced tumor formation and contributes to poor prognosis in ovarian cancer
Z. Timsah et al.
ONCOGENE (2016)
Recurrent CIC Gene Abnormalities in Angiosarcomas A Molecular Study of 120 Cases With Concurrent Investigation of PLCG1, KDR, MYC, and FLT4 Gene Alterations
Shih-Chiang Huang et al.
AMERICAN JOURNAL OF SURGICAL PATHOLOGY (2016)
FGFR1 Induces Glioblastoma Radioresistance through the PLCγ/Hif1α Pathway
Valerie Gouaze-Andersson et al.
CANCER RESEARCH (2016)
Identification of gene markers in the development of smoking-induced lung cancer
Zhao Yang et al.
GENE (2016)
MiR-30s Family Inhibit the Proliferation and Apoptosis in Human Coronary Artery Endothelial Cells Through Targeting the 3′UTR Region of ITGA4 and PLCG1
Feng Ma et al.
JOURNAL OF CARDIOVASCULAR PHARMACOLOGY (2016)
Autocrine Sonic hedgehog signaling promotes gastric cancer proliferation through induction of phospholipase Cγ1 and the ERK1/2 pathway
Zhai Ertao et al.
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2016)
Associations of mRNA:microRNA for the Shared Downstream Molecules of EGFR and Alternative Tyrosine Kinase Receptors in Non-small Cell Lung Cancer
Fengfeng Wang et al.
FRONTIERS IN GENETICS (2016)
A Small Molecule Inhibitor of PDK1/PLCγ1 Interaction Blocks Breast and Melanoma Cancer Cell Invasion
Claudio Raimondi et al.
SCIENTIFIC REPORTS (2016)
Targeting vascular endothelial growth factor (VEGF) pathway in gastric cancer: Preclinical and clinical aspects
Omar Abdel-Rahman
CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY (2015)
Anti-inflammatory activities of phospholipase C inhibitor U73122: Inhibition of monocyte-to-macrophage transformation and LPS-induced pro-inflammatory cytokine expression
Liqian Zhu et al.
INTERNATIONAL IMMUNOPHARMACOLOGY (2015)
DAG/PKCδ and IP3/Ca2+/CaMK IIβ Operate in Parallel to Each Other in PLCγ1-Driven Cell Proliferation and Migration of Human Gastric Adenocarcinoma Cells, through Akt/mTOR/S6 Pathway
Lianzhi Dai et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2015)
Integrated molecular analysis of adult T cell leukemia/lymphoma
Keisuke Kataoka et al.
NATURE GENETICS (2015)
Phospholipase C gamma 1 (PLCG1) R707Q mutation is counterselected under targeted therapy in a patient with hepatic angiosarcoma
Hans Prenen et al.
ONCOTARGET (2015)
Inhibiting the Recruitment of PLCγ1 to Kaposi's Sarcoma Herpesvirus K15 Protein Reduces the Invasiveness and Angiogenesis of Infected Endothelial Cells
Silvia Gramolelli et al.
PLOS PATHOGENS (2015)
Recurrent presence of the PLCG1 S345F mutation in nodal peripheral T-cell lymphomas
Rebeca Manso et al.
HAEMATOLOGICA (2015)
A Recurrent Activating PLCG1 Mutation in Cardiac Angiosarcomas Increases Apoptosis Resistance and Invasiveness of Endothelial Cells
Kristin Kunze et al.
CANCER RESEARCH (2014)
Metastasis of human gastric adenocarcinoma partly depends on phosphoinositide-specific phospholipase γ1 expression
Luhua Zhuang et al.
FOLIA HISTOCHEMICA ET CYTOBIOLOGICA (2014)
Phospholipase C gamma 1 is a potential prognostic biomarker for patients with locally advanced and resectable oral squamous cell carcinoma
D. Zhu et al.
INTERNATIONAL JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY (2014)
Recurrent PTPRB and PLCG1 mutations in angiosarcoma
Sam Behjati et al.
NATURE GENETICS (2014)
Competition between Grb2 and Plcγ1 for FGFR2 regulates basal phospholipase activity and invasion
Zahra Timsah et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2014)
Resistance Mechanisms for the Bruton's Tyrosine Kinase Inhibitor Ibrutinib
Jennifer A. Woyach et al.
NEW ENGLAND JOURNAL OF MEDICINE (2014)
Dysfunction of phospholipase Cγ in immune disorders and cancer
Hans Koss et al.
TRENDS IN BIOCHEMICAL SCIENCES (2014)
Vascular endothelial growth factor C promotes breast cancer progression via a novel antioxidant mechanism that involves regulation of superoxide dismutase 3
Chu-An Wang et al.
BREAST CANCER RESEARCH (2014)
Mammalian Phospholipase C
Ganesh Kadamur et al.
ANNUAL REVIEW OF PHYSIOLOGY, VOL 75 (2013)
Thioredoxin-Interacting Protein Mediates Sustained VEGFR2 Signaling in Endothelial Cells Required for Angiogenesis
Shin-Young Park et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2013)
Norepinephrine inhibits the migratory activity of pancreatic cancer cells
Anna-Maria Stock et al.
EXPERIMENTAL CELL RESEARCH (2013)
Overexpression of activated phospholipase Cγ1 is a risk factor for distant metastases in T1-T2, N0 breast cancer patients undergoing adjuvant chemotherapy
Rossano Lattanzio et al.
INTERNATIONAL JOURNAL OF CANCER (2013)
Small Molecule Inhibitors of Phospholipase C from a Novel High-throughput Screen
Weigang Huang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
Down-Regulation of miR-218-2 and Its Host Gene SLIT3 Cooperate to Promote Invasion and Progression of Thyroid Cancer
Hongyu Guan et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2013)
Phospholipase C-γ1 expression correlated with cancer progression of potentially malignant oral lesions
Li-Wei Ma et al.
JOURNAL OF ORAL PATHOLOGY & MEDICINE (2013)
Integrative Analysis of Complex Cancer Genomics and Clinical Profiles Using the cBioPortal
Jianjiong Gao et al.
SCIENCE SIGNALING (2013)
Trichostatin A reduced phospholipase C gamma-1 transcript and protein contents in MCF-7 breast cancer cells
H. Drzewiecka et al.
BIOMEDICINE & PHARMACOTHERAPY (2012)
Involvement of epidermal growth factor receptor overexpression in the promotion of breast cancer brain metastasis
Fang Nie et al.
CANCER (2012)
Migfilin Protein Promotes Migration and Invasion in Human Glioma through Epidermal Growth Factor Receptor-mediated Phospholipase C-γ and STAT3 Protein Signaling Pathways
Yunwei Ou et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Cells Transformed by PLC-Gamma 1 Overexpression are Highly Sensitive to Clostridium difficile Toxin A-Induced Apoptosis and Mitotic Inhibition
Hyo Jung Nam et al.
JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY (2012)
The interplay of HER2/HER3/PI3K and EGFR/HER2/PLC-γ1 signalling in breast cancer cell migration and dissemination
Lydia M. Balz et al.
JOURNAL OF PATHOLOGY (2012)
Epigenetic regulation of nuclear PI-PLCbeta1 signaling pathway in low-risk MDS patients during azacitidine treatment
M. Y. Follo et al.
LEUKEMIA (2012)
Activation of nuclear inositide signalling pathways during erythropoietin therapy in low-risk MDS patients
M. Y. Follo et al.
LEUKEMIA (2012)
The cBio Cancer Genomics Portal: An Open Platform for Exploring Multidimensional Cancer Genomics Data
Ethan Cerami et al.
CANCER DISCOVERY (2012)
Kaposi's Sarcoma Herpesvirus K15 Protein Contributes to Virus-Induced Angiogenesis by Recruiting PLCγ1 and Activating NFAT1-dependent RCAN1 Expression
Kiran Bala et al.
PLOS PATHOGENS (2012)
Phospholipase signalling networks in cancer
Jong Bae Park et al.
NATURE REVIEWS CANCER (2012)
Hallmarks of Cancer: The Next Generation
Douglas Hanahan et al.
CELL (2011)
Identification of Phospholipase C gamma1 as a Protein Tyrosine Phosphatase mu Substrate That Regulates Cell Migration
Polly J. Phillips-Mason et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2011)
Cross-talk between Phospho-STAT3 and PLCγ1 Plays a Critical Role in Colorectal Tumorigenesis
Peng Zhang et al.
MOLECULAR CANCER RESEARCH (2011)
The molecular biology of head and neck cancer
C. Rene Leemans et al.
NATURE REVIEWS CANCER (2011)
The SH3 domain, but not the catalytic domain, is required for phospholipase C-γ1 to mediate epidermal growth factor-induced mitogenesis
Zhongjian Xie et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2010)
A novel inhibitor of the PI3K/Akt pathway based on the structure of inositol 1,3,4,5,6-pentakisphosphate
M. Falasca et al.
BRITISH JOURNAL OF CANCER (2010)
The PI-PLC inhibitor U-73122 is a potent inhibitor of the SERCA pump in smooth muscle
M. A. Hollywood et al.
BRITISH JOURNAL OF PHARMACOLOGY (2010)
Caveolin-1 regulates VEGF-stimulated angiogenic activities in prostate cancer and endothelial cells
Salahaldin A. Tahir et al.
CANCER BIOLOGY & THERAPY (2010)
Mechanism of Phosphorylation-induced Activation of Phospholipase C-γ Isozymes
Aurelie Gresset et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
U73122, an Aminosteroid Phospholipase C Inhibitor, Is a Potent Inhibitor of Cardiac Phospholipase D by a PIP2-Dependent Mechanism
Christof Burgdorf et al.
JOURNAL OF CARDIOVASCULAR PHARMACOLOGY (2010)
HSP90 at the hub of protein homeostasis: emerging mechanistic insights
Mikko Taipale et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2010)
miR-200bc/429 cluster targets PLCγ1 and differentially regulates proliferation and EGF-driven invasion than miR-200a/141 in breast cancer
S. Uhlmann et al.
ONCOGENE (2010)
Apicidin decreases phospholipase C gamma-1 transcript and protein in Hut-78 T lymphoma cells
Szymon Debicki et al.
BIOMEDICINE & PHARMACOTHERAPY (2009)
The identification of novel PLC-γ inhibitors using virtual high throughput screening
Johannes Reynisson et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2009)
Tyrosine kinase B receptor and BDNF expression in ovarian cancers - Effect on cell migration, angiogenesis and clinical outcome
Christy W. H. Au et al.
CANCER LETTERS (2009)
The Selectivity of Receptor Tyrosine Kinase Signaling Is Controlled by a Secondary SH2 Domain Binding Site
Jae Hyun Bae et al.
CELL (2009)
Changes in choline metabolism as potential biomarkers of phospholipase Cγ1 inhibition in human prostate cancer cells
Mounia Beloueche-Babari et al.
MOLECULAR CANCER THERAPEUTICS (2009)
Phosphatidylcholine-specific phospholipase C activation in epithelial ovarian cancer cells
Francesca Spadaro et al.
CANCER RESEARCH (2008)
Phospholipase Cγ1 Is Required for Metastasis Development and Progression
Gianluca Sala et al.
CANCER RESEARCH (2008)
Combined inhibition of PLCγ-1 and c-Src abrogates epidermal growth factor receptor-mediated head and neck squamous cell carcinoma invasion
Hiroshi Nozawa et al.
CLINICAL CANCER RESEARCH (2008)
The regulatory or phosphorylation domain of p120 catenin controls E-cadherin dynamics at the plasma membrane
Yuri Fukumoto et al.
EXPERIMENTAL CELL RESEARCH (2008)
Phospholipase Cγ1 regulates the Rap GEF1-Rap1 signalling axis in the control of human prostate carcinoma cell adhesion
J. C. Peak et al.
ONCOGENE (2008)
Phosphorothiolate analogues of phosphatidylinositos as assay substrates for phospholipase C
Yinghui Liu et al.
CHEMBIOCHEM (2007)
Role of phospholipase Cγ1 in cell spreading requires association with a β-Pix/GIT1-containing complex, leading to activation of Cdc42 and Rac1
Neil P. Jones et al.
MOLECULAR AND CELLULAR BIOLOGY (2007)
PLCγ contributes to metastasis of in situ-occurring mammary and prostate tumors
C. R. Shepard et al.
ONCOGENE (2007)
The cofilin pathway in breast cancer invasion and metastasis
Weigang Wang et al.
NATURE REVIEWS CANCER (2007)
Phospholipase Cγ1 negatively regulates growth hormone signalling by forming a ternary complex with Jak2 and protein tyrosine phosphatase-1B
Jang Hyun Choi et al.
NATURE CELL BIOLOGY (2006)
Synthesis and evaluation of fluorogenic substrates for phospholipase D and phospholipase C
Tyler M. Rose et al.
ORGANIC LETTERS (2006)
NF-κB and Hsp70 are involved in the phospholipase Cγ1 signaling pathway in colorectal cancer cells
XM Li et al.
LIFE SCIENCES (2005)
Intramolecular interaction between phosphorylated tyrosine-783 and the C-terminal Src homology 2 domain activates phospholipase C-γ1
B Poulin et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Role of TGFα stimulation of the ERK, PI3 kinase and PLCγ pathways in ovarian cancer growth and migration
JM Sewell et al.
EXPERIMENTAL CELL RESEARCH (2005)
MicroRNAs: Genomics, biogenesis, mechanism, and function
DP Bartel
CELL (2004)
Phospholipase C and cofilin are required for carcinoma cell directionality in response to EGF stimulation
G Mouneimne et al.
JOURNAL OF CELL BIOLOGY (2004)
Emerging roles for p120-catenin in cell adhesion and cancer
AB Reynolds et al.
ONCOGENE (2004)
Hop: more than an Hsp70/Hsp90 adaptor protein
OO Odunuga et al.
BIOESSAYS (2004)
A core function for p120-catenin in cadherin turnover
MA Davis et al.
JOURNAL OF CELL BIOLOGY (2003)
Induction of cancer cell migration by epidermal growth factor is initiated by specific phosphorylation of tyrosine 1248 of c-erbB-2 receptor via epidermal growth factor receptor
T Dittmar et al.
FASEB JOURNAL (2002)
Absence of erythrogenesis and vasculogenesis in Plcg1-deficient mice
HJ Liao et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Share Paper
