4.5 Review

Molecular and mesoscopic geometries in autophagosome generation. A review

Related references

Note: Only part of the references are listed.
Article Cell Biology

The anti-cancer drug ABTL0812 induces ER stress-mediated cytotoxic autophagy by increasing dihydroceramide levels in cancer cells

Pau Munoz-Guardiola et al.

Summary: ABTL0812 induces cytotoxic autophagy in cancer cells by increasing cellular long-chain dihydroceramides and impairing DEGS1 activity, leading to sustained ER stress and activation of the unfolded protein response (UPR). This discovery suggests that manipulation of dihydroceramide levels could be a new therapeutic strategy for targeting cancer.

AUTOPHAGY (2021)

Article Biochemistry & Molecular Biology

Ionization properties of monophosphoinositides in mixed model membranes

Desmond Owusu Kwarteng et al.

Summary: Phosphoinositides, with low concentration in cellular membranes, play multiple roles such as signaling and membrane trafficking. Different derivatives show unique charge properties in membranes, affected by interactions with DOPE. The monophosphorylated headgroups exhibit distinct ionization behavior at various pH levels in model membranes.

BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2021)

Article Multidisciplinary Sciences

An N-terminal conserved region in human Atg3 couples membrane curvature sensitivity to conjugase activity during autophagy

Yansheng Ye et al.

Summary: The enzyme Atg3 is crucial for autophagosome formation, facilitating the connection of LC3 to PE lipids. The N-terminal conserved region of human Atg3 communicates information from the curvature-sensing domain to the active site, promoting spatial regulation of LC3-PE conjugation on target membranes.

NATURE COMMUNICATIONS (2021)

Article Biochemistry & Molecular Biology

Lipid profiles of autophagic structures isolated from wild type and Atg2 mutant Drosophila

Hajnalka Laczko-Dobos et al.

Summary: Autophagy is a crucial catabolic and recycling process for cellular health, with Atg2 protein playing a significant role in the lipid composition of autophagic membranes, particularly in the transport of short fatty acyl chain PE species. The lipidomic analysis reveals dynamic changes in lipid composition during autophagic membrane maturation.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS (2021)

Review Biochemistry & Molecular Biology

Mitophagy in tumorigenesis and metastasis

Logan P. Poole et al.

Summary: Cells utilize mitophagy to remove dysfunctional or excess mitochondria in response to external stresses, with mechanisms including mitochondrial cargo receptors induced by these stresses, mitochondrial protein targets of PINK1/Parkin phospho-ubiquitination, and mitochondrial lipid signaling. These pathways play a crucial role in tumorigenesis, metastasis, cell cycle control, survival pathways, and therapy responses in cancer. Mitophagy also impacts tissue atrophy during cancer cachexia and clinical therapy responses.

CELLULAR AND MOLECULAR LIFE SCIENCES (2021)

Review Cell Biology

Autophagosome biogenesis comes out of the black box

Chunmei Chang et al.

Summary: This review discusses the recent discoveries regarding the molecular mechanisms of autophagosome formation, emphasizing the assembly of cargo receptors and core machinery during the process. It also addresses emerging questions in the field of autophagosome formation.

NATURE CELL BIOLOGY (2021)

Article Biochemistry & Molecular Biology

Phosphoproteomic identification of ULK substrates reveals VPS15-dependent ULK/VPS34 interplay in the regulation of autophagy

Thomas John Mercer et al.

Summary: Autophagy is regulated by ULK and VPS15 through phosphorylation, affecting the formation and activity of autophagosomes. The study reveals the crucial role of VPS15 in autophagy and its association with ULK.

EMBO JOURNAL (2021)

Article Biochemistry & Molecular Biology

PKCε controls the fusion of secretory vesicles in mast cells in a phosphatidic acid-dependent mode

Emilio M. Serrano-Lopez et al.

Summary: PKC epsilon is highly expressed in mast cells and its activation by acidic phospholipids, specifically phosphatidic acid (PA), leads to increased vesicle degranulation and SNAP23 phosphorylation, indicating a role in the allergic reaction. This study identified a molecular mechanism involving a collection of Arg residues in the C1B domain of PKC epsilon that selectively binds to PA, resulting in plasma membrane translocation and increased vesicle secretion. These findings highlight the importance of PA signaling in regulating PKC epsilon activity, which could be a potential target for controlling allergic responses.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2021)

Review Cell Biology

Lipids and membrane-associated proteins in autophagy

Linsen Li et al.

Summary: Autophagy is crucial for maintaining cellular homeostasis, and is regulated by membrane-driven processes and proteins. This review focuses on the membrane lipid composition, membrane-associated proteins, and three key membrane remodeling processes in autophagy. It also discusses the significance of these findings and potential future research directions in this field. Additionally, various biochemical techniques and assays for studying membrane properties in autophagy are summarized.

PROTEIN & CELL (2021)

Review Cell Biology

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

Daniel J. Klionsky et al.

Summary: The guidelines presented in this article aim to assist researchers in selecting and interpreting methods to examine autophagy, as well as to help reviewers provide constructive critiques of reports focused on these processes. It emphasizes that no single assay is perfect for every situation, and multiple techniques may be needed to properly monitor autophagy in different experimental settings. The article also highlights the importance of targeting multiple autophagy-related genes in genetic approaches to block autophagy effectively.

AUTOPHAGY (2021)

Review Biochemistry & Molecular Biology

Lipids and Lipid-Binding Proteins in Selective Autophagy

Laura R. de la Ballina et al.

JOURNAL OF MOLECULAR BIOLOGY (2020)

Article Biochemistry & Molecular Biology

Local Fatty Acid Channeling into Phospholipid Synthesis Drives Phagophore Expansion during Autophagy

Maximilian Schuetter et al.

Article Multidisciplinary Sciences

Phase separation organizes the site of autophagosome formation

Yuko Fujioka et al.

NATURE (2020)

Review Cell Biology

Autophagosome biogenesis: From membrane growth to closure

Thomas J. Melia et al.

JOURNAL OF CELL BIOLOGY (2020)

Review Cell Biology

Activation and targeting of ATG8 protein lipidation

Sascha Martens et al.

CELL DISCOVERY (2020)

Review Cell Biology

Emerging roles of ATG proteins and membrane lipids in autophagosome formation

Taki Nishimura et al.

CELL DISCOVERY (2020)

Review Cell Biology

Liquid-liquid phase separation in autophagy

Nobuo N. Noda et al.

JOURNAL OF CELL BIOLOGY (2020)

Review Biochemistry & Molecular Biology

The Golgi as an Assembly Line to the Autophagosome

Stefano De Tito et al.

TRENDS IN BIOCHEMICAL SCIENCES (2020)

Article Biochemistry & Molecular Biology

Structure, lipid scrambling activity and role in autophagosome formation of ATG9A

Shintaro Maeda et al.

NATURE STRUCTURAL & MOLECULAR BIOLOGY (2020)

Article Biochemistry & Molecular Biology

Atg9 is a lipid scramblase that mediates autophagosomal membrane expansion

Kazuaki Matoba et al.

NATURE STRUCTURAL & MOLECULAR BIOLOGY (2020)

Article Multidisciplinary Sciences

Reconstitution of autophagosome nucleation defines Atg9 vesicles as seeds for membrane formation

Justyna Sawa-Makarska et al.

SCIENCE (2020)

Article Cell Biology

Regulation of LC3 lipidation by the autophagy-specific class III phosphatidylinositol-3 kinase complex

Livia W. Brier et al.

MOLECULAR BIOLOGY OF THE CELL (2019)

Article Biochemistry & Molecular Biology

Atg2 mediates direct lipid transfer between membranes for autophagosome formation

Takuo Osawa et al.

NATURE STRUCTURAL & MOLECULAR BIOLOGY (2019)

Article Biochemistry & Molecular Biology

Intrinsic lipid binding activity of ATG16L1 supports efficient membrane anchoring and autophagy

Leo J. Dudley et al.

EMBO JOURNAL (2019)

Article Cell Biology

ATG2 transports lipids to promote autophagosome biogenesis

Diana P. Valverde et al.

JOURNAL OF CELL BIOLOGY (2019)

Article Cell Biology

VPS37A directs ESCRT recruitment for phagophore closure

Yoshinori Takahashi et al.

JOURNAL OF CELL BIOLOGY (2019)

Review Biochemistry & Molecular Biology

Intricate role of mitochondrial lipid in mitophagy and mitochondrial apoptosis: its implication in cancer therapeutics

Prakash P. Praharaj et al.

CELLULAR AND MOLECULAR LIFE SCIENCES (2019)

Review Biochemistry & Molecular Biology

Rafts: A nickname for putative transient nanodomains

Felix M. Goni

CHEMISTRY AND PHYSICS OF LIPIDS (2019)

Article Biology

Membrane curvature induces cardiolipin sorting

Elena Beltran-Heredia et al.

COMMUNICATIONS BIOLOGY (2019)

Article Biochemistry & Molecular Biology

A lysosome-plasma membrane-sphingolipid axis linking lysosomal storage to cell growth arrest

Maura Samarani et al.

FASEB JOURNAL (2018)

Review Physics, Applied

The 2018 biomembrane curvature and remodeling roadmap

Patricia Bassereau et al.

JOURNAL OF PHYSICS D-APPLIED PHYSICS (2018)

Review Biophysics

The Physical Properties of Ceramides in Membranes

Alicia Alonso et al.

ANNUAL REVIEW OF BIOPHYSICS, VOL 47 (2018)

Article Multidisciplinary Sciences

Insights into autophagosome biogenesis from structural and biochemical analyses of the ATG2A-WIPI4 complex

Saikat Chowdhury et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)

Editorial Material Cell Biology

Fusion and scission of membranes: Ubiquitous topological transformations in cells

Roland L. Knorr et al.

TRAFFIC (2017)

Article Multidisciplinary Sciences

Human ATG3 binding to lipid bilayers: role of lipid geometry, and electric charge

Javier H. Hervas et al.

SCIENTIFIC REPORTS (2017)

Article Biochemistry & Molecular Biology

Known unknowns of cardiolipin signaling: The best is yet to come

John J. Maguire et al.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS (2017)

Article Biochemistry & Molecular Biology

Magic angle spinning 31P NMR spectroscopy reveals two essentially identical ionization states for the cardiolipin phosphates in phospholipid liposomes

E. E. Kooijman et al.

BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2017)

Review Biochemistry & Molecular Biology

Molecular definitions of autophagy and related processes

Lorenzo Galluzzi et al.

EMBO JOURNAL (2017)

Review Biochemistry & Molecular Biology

Regulation of autophagy by mitochondrial phospholipids in health and diseases

Paul Hsu et al.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS (2017)

Article Cell Biology

Excess sphingomyelin disturbs ATG9A trafficking and autophagosome closure

Elisabeth Corcelle-Termeau et al.

AUTOPHAGY (2016)

Article Biochemistry & Molecular Biology

Protein-lipid interactions and non-lamellar lipidic structures in membrane pore formation and membrane fusion

Robert J. C. Gilbert

BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2016)

Review Biochemistry & Molecular Biology

Recent progress on lipid lateral heterogeneity in plasma membranes: From rafts to submicrometric domains

Melanie Carquin et al.

PROGRESS IN LIPID RESEARCH (2016)

Review Biochemistry & Molecular Biology

Complex Relations Between Phospholipids, Autophagy, and Neutral Lipids

Oren Shatz et al.

TRENDS IN BIOCHEMICAL SCIENCES (2016)

Review Cell Biology

Digesting the Expanding Mechanisms of Autophagy

Nicholas T. Ktistakis et al.

TRENDS IN CELL BIOLOGY (2016)

Article Multidisciplinary Sciences

The Atg1-kinase complex tethers Atg9-vesicles to initiate autophagy

Yijian Rao et al.

NATURE COMMUNICATIONS (2016)

Article Multidisciplinary Sciences

Autophagy initiation by ULK complex assembly on ER tubulovesicular regions marked by ATG9 vesicles

Eleftherios Karanasios et al.

NATURE COMMUNICATIONS (2016)

Article Multidisciplinary Sciences

HS1BP3 negatively regulates autophagy by modulation of phosphatidic acid levels

Petter Holland et al.

NATURE COMMUNICATIONS (2016)

Review Biophysics

Mechanisms of Autophagy

Nobuo N. Noda et al.

ANNUAL REVIEW OF BIOPHYSICS, VOL 44 (2015)

Article Cell Biology

Autophagosome closure requires membrane scission

Roland L. Knorr et al.

AUTOPHAGY (2015)

Review Biochemistry & Molecular Biology

Ceramide induced mitophagy and tumor suppression

Mohammed Dany et al.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2015)

Article Biochemistry & Molecular Biology

Relaxation of Loaded ESCRT-III Spiral Springs Drives Membrane Deformation

Nicolas Chiaruttini et al.

Review Biochemistry & Molecular Biology

Atg1 family kinases in autophagy initiation

Nobuo N. Noda et al.

CELLULAR AND MOLECULAR LIFE SCIENCES (2015)

Article Biochemistry & Molecular Biology

Fluctuation dynamics of bilayer vesicles with intermonolayer sliding: Experiment and theory

Michael Mell et al.

CHEMISTRY AND PHYSICS OF LIPIDS (2015)

Article Biophysics

Thermally-induced aggregation and fusion of protein-free lipid vesicles

Maitane Ibarguren et al.

COLLOIDS AND SURFACES B-BIOINTERFACES (2015)

Article Biochemistry & Molecular Biology

Membrane tension and membrane fusion

Michael M. Kozlov et al.

CURRENT OPINION IN STRUCTURAL BIOLOGY (2015)

Article Biochemistry & Molecular Biology

PI3P binding by Atg21 organises Atg8 lipidation

Lisa Juris et al.

EMBO JOURNAL (2015)

Review Cell Biology

When Physics Takes Over: BAR Proteins and Membrane Curvature

Mijo Simunovic et al.

TRENDS IN CELL BIOLOGY (2015)

Editorial Material Cell Biology

The ER-Golgi intermediate compartment feeds the phagophore membrane

Liang Ge et al.

AUTOPHAGY (2014)

Review Biochemistry & Molecular Biology

The basic structure and dynamics of cell membranes: An update of the Singer-Nicolson model

Felix M. Goni

BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2014)

Review Biochemistry & Molecular Biology

Atomistic Autophagy: The Structures of Cellular Self-Digestion

James H. Hurley et al.

Review Cell Biology

A current perspective of autophagosome biogenesis

Shusaku T. Shibutani et al.

CELL RESEARCH (2014)

Review Cell Biology

Organellophagy: Eliminating cellular building blocks via selective autophagy

Koji Okamoto

JOURNAL OF CELL BIOLOGY (2014)

Article Biochemistry & Molecular Biology

WIPI2 Links LC3 Conjugation with PI3P, Autophagosome Formation, and Pathogen Clearance by Recruiting Atg12-5-16L1

Hannah C. Dooley et al.

MOLECULAR CELL (2014)

Review Multidisciplinary Sciences

Lipid landscapes and pipelines in membrane homeostasis

Joost C. M. Holthuis et al.

NATURE (2014)

Review Cell Biology

Cargo recognition and trafficking in selective autophagy

Alexandra Stolz et al.

NATURE CELL BIOLOGY (2014)

Review Cell Biology

The return of the nucleus: transcriptional and epigenetic control of autophagy

Jens Fullgrabe et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2014)

Review Biochemistry & Molecular Biology

At the end of the autophagic road: an emerging understanding of lysosomal functions in autophagy

Han-Ming Shen et al.

TRENDS IN BIOCHEMICAL SCIENCES (2014)

Review Cell Biology

The beginning of the end: how scaffolds nucleate autophagosome biogenesis

Robin E. Stanley et al.

TRENDS IN CELL BIOLOGY (2014)

Article Multidisciplinary Sciences

A sub-nanometre view of how membrane curvature and composition modulate lipid packing and protein recruitment

Stefano Vanni et al.

NATURE COMMUNICATIONS (2014)

Editorial Material Cell Biology

Unveiling the last missing link of the cardiolipin synthetic pathway in mitochondria

Yasushi Tamura et al.

AGING-US (2013)

Editorial Material Cell Biology

Dissecting the role of the Atg12-Atg5-Atg16 complex during autophagosome formation

Marta Walczak et al.

AUTOPHAGY (2013)

Article Biochemistry & Molecular Biology

The pseudokinase tribbles homologue-3 plays a crucial role in cannabinoid anticancer action

Maria Salazar et al.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS (2013)

Review Biochemistry & Molecular Biology

Cardiolipin remodeling and the function of tafazzin

Michael Schlame

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS (2013)

Article Biophysics

Lateral pressure change on phase transitions of phosphatidylcholine/diolein mixed membranes

Tomoari Kamo et al.

COLLOIDS AND SURFACES B-BIOINTERFACES (2013)

Article Cell Biology

Up-to-date membrane biogenesis in the autophagosome formation

Maho Hamasaki et al.

CURRENT OPINION IN CELL BIOLOGY (2013)

Article Chemistry, Multidisciplinary

Bilayer Thickness Mismatch Controls Domain Size in Model Membranes

Frederick A. Heberle et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2013)

Article Cell Biology

Deacylation on the matrix side of the mitochondrial inner membrane regulates cardiolipin remodeling

Matthew G. Baile et al.

MOLECULAR BIOLOGY OF THE CELL (2013)

Article Cell Biology

ER exit sites are physical and functional core autophagosome biogenesis components

Martin Graef et al.

MOLECULAR BIOLOGY OF THE CELL (2013)

Review Cell Biology

The autophagosome: origins unknown, biogenesis complex

Christopher A. Lamb et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2013)

Article Multidisciplinary Sciences

Ionization Constants pKa of Cardiolipin

Gerd Olofsson et al.

PLOS ONE (2013)

Article Chemistry, Physical

Monolayer spontaneous curvature of raft-forming membrane lipids

Benjamin Kollmitzer et al.

SOFT MATTER (2013)

Review Oncology

Ceramide-orchestrated signalling in cancer cells

Samy A. F. Morad et al.

NATURE REVIEWS CANCER (2013)

Article Biochemistry & Molecular Biology

Architecture of the Atg17 Complex as a Scaffold for Autophagosome Biogenesis

Michael J. Ragusa et al.

Review Cell Biology

Autophagy: for better or for worse

Ellen Wirawan et al.

CELL RESEARCH (2012)

Review Biochemistry & Molecular Biology

Mechanisms of Autophagosome Biogenesis

David C. Rubinsztein et al.

CURRENT BIOLOGY (2012)

Article Biochemistry & Molecular Biology

Ceramide targets autophagosomes to mitochondria and induces lethal mitophagy

R. David Sentelle et al.

NATURE CHEMICAL BIOLOGY (2012)

Review Biochemistry & Molecular Biology

Phospholipases C and sphingomyelinases: Lipids as substrates and modulators of enzyme activity

Felix M. Goni et al.

PROGRESS IN LIPID RESEARCH (2012)

Review Biochemistry & Molecular Biology

The complexity of cardiolipin in health and disease

Steven M. Claypool et al.

TRENDS IN BIOCHEMICAL SCIENCES (2012)

Review Biochemistry & Molecular Biology

Mechanisms of Membrane Curvature Sensing

Bruno Antonny

ANNUAL REVIEW OF BIOCHEMISTRY, VOL 80 (2011)

Review Cell Biology

The Role of Atg Proteins in Autophagosome Formation

Noboru Mizushima et al.

ANNUAL REVIEW OF CELL AND DEVELOPMENTAL BIOLOGY, VOL 27 (2011)

Article Biochemistry & Molecular Biology

SNARE Proteins Are Required for Macroautophagy

Usha Nair et al.

Review Chemistry, Multidisciplinary

Sphingolipid and Glycosphingolipid Metabolic Pathways in the Era of Sphingolipidomics

Alfred H. Merrill

CHEMICAL REVIEWS (2011)

Article Biochemistry & Molecular Biology

Mitochondria regulate autophagy by conserved signalling pathways

Martin Graef et al.

EMBO JOURNAL (2011)

Article Biochemistry & Molecular Biology

Structural Basis of Atg8 Activation by a Homodimeric E1, Atg7

Nobuo N. Noda et al.

MOLECULAR CELL (2011)

Article Biochemistry & Molecular Biology

Insights into noncanonical E1 enzyme activation from the structure of autophagic E1 Atg7 with Atg8

Seung Beom Hong et al.

NATURE STRUCTURAL & MOLECULAR BIOLOGY (2011)

Article Multidisciplinary Sciences

Key Role of Polyphosphoinositides in Dynamics of Fusogenic Nuclear Membrane Vesicles

Vanessa Zhendre et al.

PLOS ONE (2011)

Article Biochemistry & Molecular Biology

End-products diacylglycerol and ceramide modulate membrane fusion induced by a phospholipase C/sphingomyelinase from Pseudomonas aeruginosa

Maitane Ibarguren et al.

BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2010)

Article Biochemistry & Molecular Biology

LC3 and GATE-16/GABARAP subfamilies are both essential yet act differently in autophagosome biogenesis

Hilla Weidberg et al.

EMBO JOURNAL (2010)

Article Biochemistry & Molecular Biology

Activation of protein kinase C-α is essential for stimulation of cell proliferation by ceramide 1-phosphate

Patricia Gangoiti et al.

FEBS LETTERS (2010)

Review Biochemistry & Molecular Biology

Ceramide-rich platforms in transmembrane signaling

Branka Stancevic et al.

FEBS LETTERS (2010)

Review Cell Biology

The role of membrane proteins in mammalian autophagy

Sharon A. Tooze

SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY (2010)

Review Biochemistry & Molecular Biology

Effects of ceramide and other simple sphingolipids on membrane lateral structure

Felix M. Goni et al.

BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2009)

Article Biochemistry & Molecular Biology

Role of JNK1-dependent Bcl-2 Phosphorylation in Ceramide-induced Macroautophagy

Sophie Pattingre et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2009)

Article Biochemistry & Molecular Biology

Complex Lipid Requirements for SNARE- and SNARE Chaperone-dependent Membrane Fusion

Joji Mima et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2009)

Article Medicine, Research & Experimental

Cannabinoid action induces autophagy-mediated cell death through stimulation of ER stress in human glioma cells

Maria Salazar et al.

JOURNAL OF CLINICAL INVESTIGATION (2009)

Article Multidisciplinary Sciences

Nuclear Envelope Remnants: Fluid Membranes Enriched in STEROLS and Polyphosphoinositides

Marie Garnier-Lhomme et al.

PLOS ONE (2009)

Article Multidisciplinary Sciences

Phosphoinositides and SNARE chaperones synergistically assemble and remodel SNARE complexes for membrane fusion

Joji Mima et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)

Article Cell Biology

Dynamics and function of PtdIns(3)P in autophagy

Keisuke Obara et al.

AUTOPHAGY (2008)

Editorial Material Cell Biology

Autophagy revisited

Daniel J. Klionsky

AUTOPHAGY (2008)

Review Biochemistry & Molecular Biology

Phase diagrams of lipid mixtures relevant to the study of membrane rafts

Felix M. Goni et al.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS (2008)

Review Biochemistry & Molecular Biology

Autophagy in the pathogenesis of disease

Beth Levine et al.

Review Cell Biology

Membrane recognition by phospholipid-binding domains

Mark A. Lemmon

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2008)

Review Biochemistry & Molecular Biology

Mechanics of membrane fusion

Leonid V. Chernomordik et al.

NATURE STRUCTURAL & MOLECULAR BIOLOGY (2008)

Article Biochemistry & Molecular Biology

Ceramide:: Physiological and pathophysiological aspects

Marcus Schenck et al.

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2007)

Article Biochemistry & Molecular Biology

Cardiolipin: Setting the beat of apoptosis

Francois Gonzalvez et al.

APOPTOSIS (2007)

Review Biochemistry & Molecular Biology

Biological aspects of ceramide-enriched membrane domains

Heike Grassme et al.

PROGRESS IN LIPID RESEARCH (2007)

Article Cell Biology

Atg9 trafficking in mammalian cells

Jernma L. Webber et al.

AUTOPHAGY (2007)

Review Biochemistry & Molecular Biology

Membranes are not just rafts

Saame Raza Shaikh et al.

CHEMISTRY AND PHYSICS OF LIPIDS (2006)

Review Biochemistry & Molecular Biology

Membrane binding domains

James H. Hurley

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS (2006)

Review Cell Biology

How proteins produce cellular membrane curvature

J Zimmerberg et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2006)

Review Biochemistry & Molecular Biology

Seeing spots: Complex phase behavior in simple membranes

SL Veatch et al.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2005)

Article Biochemistry & Molecular Biology

What makes the bioactive lipids phosphatidic acid and lysophosphatidic acid so special?

EE Kooijman et al.

BIOCHEMISTRY (2005)

Review Biochemistry & Molecular Biology

Membrane hemifusion: Crossing a chasm in two leaps

LV Chernomordik et al.

Article Biochemistry & Molecular Biology

Hemifusion in SNARE-mediated membrane fusion

YB Xu et al.

NATURE STRUCTURAL & MOLECULAR BIOLOGY (2005)

Review Oncology

Biologically active sphingolipids in cancer pathogenesis and treatment

B Ogretmen et al.

NATURE REVIEWS CANCER (2004)

Article Biophysics

Curvature and bending constants for phosphatidylserine-containing membranes

N Fuller et al.

BIOPHYSICAL JOURNAL (2003)

Review Cell Biology

Sphingosine-1-phosphate: An enigmatic signalling lipid

S Spiegel et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2003)

Article Biochemistry & Molecular Biology

Non-permanent proteins in membranes:: when proteins come as visitors (review)

FM Goñi

MOLECULAR MEMBRANE BIOLOGY (2002)

Article Biophysics

Stalk model of membrane fusion: Solution of energy crisis

Y Kozlovsky et al.

BIOPHYSICAL JOURNAL (2002)

Article Biochemistry & Molecular Biology

Diacylglycerol effects on phosphatidylinositol-specific phospholipase C activity and vesicle fusion

AV Villar et al.

FEBS LETTERS (2001)

Review Biochemistry & Molecular Biology

Membrane fusion induced by phospholipase C and sphingomyelinases

FM Goñi et al.

BIOSCIENCE REPORTS (2000)

Review Cell Biology

Ceramide in the eukaryotic stress response

YA Hannun et al.

TRENDS IN CELL BIOLOGY (2000)