4.6 Article

FoxO3a cooperates with RUNX1 to promote chondrogenesis and terminal hypertrophic of the chondrogenic progenitor cells

Related references

Note: Only part of the references are listed.
Article Cell Biology

Over-expression of MEG3 promotes differentiation of bone marrow mesenchymal stem cells into chondrocytes by regulating miR-129-5p/RUNX1 axis

Jun Zhu et al.

Summary: This study investigated the role of MEG3 in cartilage differentiation of bone marrow mesenchymal stem cells (BMSCs) by promoting cell viability and differentiation, upregulating the expression of chondrocyte-related genes, and inhibiting miR-129-5p. The regulatory effects of MEG3 and miR-129-5p were confirmed through rescue experiments. The study provides a basis for the application of lncRNA in articular cartilage injury.

CELL CYCLE (2021)

Article Biochemistry & Molecular Biology

Decoding molecular interplay between RUNX1 and FOXO3a underlying the pulsatile IGF1R expression during acquirement of chemoresistance

Ajit C. Dhadve et al.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2020)

Article Biochemistry & Molecular Biology

Runt-related transcription factor 1 is required for murine osteoblast differentiation and bone formation

Jun Tang et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2020)

Review Biochemistry & Molecular Biology

Role of Forkhead Box O Transcription Factors in Oxidative Stress-Induced Chondrocyte Dysfunction: Possible Therapeutic Target for Osteoarthritis?

Rikang Wang et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)

Article Biochemistry & Molecular Biology

Forkhead box O transcription factors in chondrocytes regulate endochondral bone formation

G. Eelen et al.

JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY (2016)

Article Orthopedics

Dysregulated FOXO transcription factors in articular cartilage in aging and osteoarthritis

Y. Akasaki et al.

OSTEOARTHRITIS AND CARTILAGE (2014)

Article Rheumatology

FoxO Transcription Factors Support Oxidative Stress Resistance in Human Chondrocytes

Yukio Akasaki et al.

ARTHRITIS & RHEUMATOLOGY (2014)

Article Rheumatology

A novel disease-modifying osteoarthritis drug candidate targeting Runx1

Fumiko Yano et al.

ANNALS OF THE RHEUMATIC DISEASES (2013)

Article Biochemistry & Molecular Biology

ATDC5: An excellent in vitro model cell line for skeletal development

Yongchang Yao et al.

JOURNAL OF CELLULAR BIOCHEMISTRY (2013)

Article Medicine, Research & Experimental

FOXOs attenuate bone formation by suppressing Wnt signaling

Srividhya Iyer et al.

JOURNAL OF CLINICAL INVESTIGATION (2013)

Article Biochemistry & Molecular Biology

Genome-wide analysis of FOXO3 mediated transcription regulation through RNA polymerase II profiling

Astrid Eijkelenboom et al.

MOLECULAR SYSTEMS BIOLOGY (2013)

Review Rheumatology

Osteoarthritis: A disease of the joint as an organ

Richard F. Loeser et al.

ARTHRITIS AND RHEUMATISM (2012)

Article Endocrinology & Metabolism

Runx1 dose-dependently regulates endochondral ossification during skeletal development and fracture healing

Do Y. Soung et al.

JOURNAL OF BONE AND MINERAL RESEARCH (2012)

Article Endocrinology & Metabolism

FOXO1 modulates osteoblast differentiation

Michelle F. Siqueira et al.

Article Endocrinology & Metabolism

TNF-α Mediates Diabetes-Enhanced Chondrocyte Apoptosis During Fracture Healing and Stimulates Chondrocyte Apoptosis Through FOX01

Rayyan A. Kayal et al.

JOURNAL OF BONE AND MINERAL RESEARCH (2010)

Article Engineering, Biomedical

Are FoxO transcription factors implicated in osteoarthritis? Influence of Diacerhein

N. de Isla et al.

BIO-MEDICAL MATERIALS AND ENGINEERING (2010)

Article Developmental Biology

Akt regulates skeletal development through GSK3, mTOR, and FoxOs

Satoshi Rokutanda et al.

DEVELOPMENTAL BIOLOGY (2009)

Article Biochemistry & Molecular Biology

Runx1 Is a Co-activator with FOXO3 to Mediate Transforming Growth Factor β (TGFβ)-induced Bim Transcription in Hepatic Cells

Gary M. Wildey et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2009)

Article Endocrinology & Metabolism

Runx1/AML1/Cbfa2 mediates onset of mesenchymal cell differentiation toward chondrogenesis

YJ Wang et al.

JOURNAL OF BONE AND MINERAL RESEARCH (2005)

Review Oncology

The RUNX genes: Gain or loss of function in cancer

K Blyth et al.

NATURE REVIEWS CANCER (2005)

Article Cell Biology

Runx1/AML1 hematopoietic transcription factor contributes to skeletal development in vivo

JB Lian et al.

JOURNAL OF CELLULAR PHYSIOLOGY (2003)

Article Biochemistry & Molecular Biology

Upstream and downstream targets of RUNX proteins

F Otto et al.

JOURNAL OF CELLULAR BIOCHEMISTRY (2003)