4.6 Article

LncRNA NONHSAT009968 inhibits the osteogenic differentiation of hBMMSCs in SA-induced inflammation via Wnt3a

Related references

Note: Only part of the references are listed.
Article Orthopedics

The AO trauma CPP bone infection registry: Epidemiology and outcomes ofStaphylococcus aureusbone infection

Mario Morgenstern et al.

Summary: Bone infection after orthopedic surgery, often caused by Staphylococcus aureus, was studied in a multinational registry with 292 patients. Most patients showed improvement after 6 and 12 months of treatment, but the SF-36 physical component summary score did not reach 50 at 12 months. The study ended with a 62.1% cure rate, with worse patient-reported outcomes for those with methicillin-resistant S. aureus infections at the 12-month follow-up.

JOURNAL OF ORTHOPAEDIC RESEARCH (2021)

Review Orthopedics

Use of contemporary biomaterials in chronic osteomyelitis treatment: Clinical lessons learned and literature review

Jan A. P. Geurts et al.

Summary: Chronic osteomyelitis poses challenges in treatment due to bone infection and bacterial biofilm eradication. Novel biomaterials with unique properties are increasingly used to combat infection in this context, with ongoing debate about focusing on bone regeneration or antimicrobial properties.

JOURNAL OF ORTHOPAEDIC RESEARCH (2021)

Review Chemistry, Applied

Chitosan-based drug delivery systems: From synthesis strategy to osteomyelitis treatment - A review

Fenghua Tao et al.

Summary: Chitosan, a cationic polysaccharide extracted from chitin, has gained attention in bacterial inhibition and drug delivery. Local antibiotic delivery after surgical debridement using chitosan-based biomaterials is effective in overcoming antibiotic resistance and reducing systemic toxicity in the treatment of osteomyelitis. This review highlights recent advances and future perspectives in utilizing chitosan-based drug delivery systems for osteomyelitis treatment.

CARBOHYDRATE POLYMERS (2021)

Article Orthopedics

Novel microcomposite implant for the controlled delivery of antibiotics in the treatment of osteomyelitis following total joint replacement

Serkan Inceoglu et al.

Summary: This study successfully developed a novel microcomposite implant capable of continuously releasing high concentrations of antibiotics, effectively eradicating infections while maintaining adequate mechanical strength, offering new possibilities for the treatment of osteomyelitis.

JOURNAL OF ORTHOPAEDIC RESEARCH (2021)

Article Orthopedics

Distinct expression trend of signature antigens of Staphylococcus aureus osteomyelitis correlated with clinical outcomes

Wei Fu et al.

Summary: The study highlights that dynamic changes in specific antigens of Staphylococcus aureus osteomyelitis patients can serve as predictive markers for clinical outcomes.

JOURNAL OF ORTHOPAEDIC RESEARCH (2021)

Article Oncology

The umbilical cord mesenchymal stem cell-derived exosomal lncRNA H19 improves osteochondral activity through miR-29b-3p/FoxO3 axis

Litao Yan et al.

Summary: This study found that exosomal lncRNA H19 derived from UMSCs acts as a competing endogenous RNA to enhance osteochondral activity in chondrocytes by sequestering miR-29b-3p. Injection of exosomes overexpressing H19 promoted sustained cartilage repair, highlighting its potential for developing strategies against cartilage defects.

CLINICAL AND TRANSLATIONAL MEDICINE (2021)

Article Medicine, Research & Experimental

lncRNA SNHG10 Promotes the Proliferation and Invasion of Osteosarcoma via Wnt/β-Catenin Signaling

Shutao Zhu et al.

MOLECULAR THERAPY-NUCLEIC ACIDS (2020)

Review Microbiology

Methicillin-resistant Staphylococcus aureus: an overview of basic and clinical research

Nicholas A. Turner et al.

NATURE REVIEWS MICROBIOLOGY (2019)

Article Biochemistry & Molecular Biology

IncRNA MIR100HG-derived miR-100 and miR-125b mediate cetuximab resistance via Wnt/β-catenin signaling

Yuanyuan Lu et al.

NATURE MEDICINE (2017)

Article Biochemistry & Molecular Biology

PDGF-regulated miRNA-138 inhibits the osteogenic differentiation of mesenchymal stem cells

Bo Qu et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2014)