4.1 Article

Successful secukinumab treatment of active bullous pemphigoid and chronic severe psoriasis: a case report

Journal

AUSTRALASIAN JOURNAL OF DERMATOLOGY
Volume 63, Issue 2, Pages E155-E158

Publisher

WILEY
DOI: 10.1111/ajd.13803

Keywords

bullous pemphigoid; immunobullous; interleukin-17; monoclonal antibody; psoriasis

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This case report demonstrates the first case of secukinumab achieving a dramatic clinical improvement of both chronic psoriasis and active BP.
Since the concurrence of bullous pemphigoid (BP) and psoriasis was first reported in 1929, an increasing number of studies has been published to analyse their relationship in recent years. However, the pathogenesis of the concurrence is not yet well understood, and the coexistence of the two conditions imposes a difficult therapeutic challenge. This case report demonstrates the first case of secukinumab achieving a dramatic clinical improvement of both chronic psoriasis and active BP.

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