Probiotics, prebiotics and synbiotics: Safe options for next-generation therapeutics

Probiotics have been considered as an economical and safe alternative for the treatment of a large number of chronic diseases and improvement of human health. They are known to modulate the host immunity and protect from several infectious and non-infectious diseases. The colonization, killing of pathogens and induction of host cells are few of the important probiotic attributes which affect several functions of the host. In addition, prebiotics and non-digestible food substances selectively promote the growth of probiotics and human health through nutrient enrichment, and modulation of gut microbiota and immune system. This review highlights the role of probiotics and prebiotics alone and in combination (synbiotics) in the modulation of immune system, treatment of infections, management of inflammatory bowel disease and cancer therapy.

Automated summary

Probiotics are an economical and safe alternative for treating chronic diseases and improving human health. They modulate the host immunity and protect against infectious and non-infectious diseases. Additionally, prebiotics and non-digestible food substances promote the growth of probiotics and human health through modulation of gut microbiota and immune system.