Related references
Note: Only part of the references are listed.A helicase-primase drug candidate with sufficient target tissue exposure affects latent neural herpes simplex virus infections
Christian Gege et al.
SCIENCE TRANSLATIONAL MEDICINE (2021)
Efficacy of pritelivir and acyclovir in the treatment of herpes simplex virus infections in a mouse model of herpes simplex encephalitis
Debra C. Quenelle et al.
ANTIVIRAL RESEARCH (2018)
Profile of anti-herpetic action of ASP2151 (amenamevir) as a helicase-primase inhibitor
Misako Yajima et al.
ANTIVIRAL RESEARCH (2017)
Effect of Pritelivir Compared With Valacyclovir on Genital HSV-2 Shedding in Patients With Frequent Recurrences A Randomized Clinical Trial
Anna Wald et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2016)
Subclinical generation of acyclovir-resistant herpes simplex virus with mutation of homopolymeric guanosine strings during acyclovir therapy
Tohru Daikoku et al.
JOURNAL OF DERMATOLOGICAL SCIENCE (2016)
HSV antivirals - current and future treatment options
Alexander Birkmann et al.
CURRENT OPINION IN VIROLOGY (2016)
Global and Regional Estimates of Prevalent and Incident Herpes Simplex Virus Type 1 Infections in 2012
Katharine J. Looker et al.
PLOS ONE (2015)
Resistance of herpes simplex viruses to acyclovir: An update from a ten-year survey in France
Emilie Frobert et al.
ANTIVIRAL RESEARCH (2014)
Characterization of virus strains resistant to the herpes virus helicase-primase inhibitor ASP2151 (Amenamevir)
Koji Chono et al.
BIOCHEMICAL PHARMACOLOGY (2012)
Resistance of Herpes Simplex Viruses to Nucleoside Analogues: Mechanisms, Prevalence, and Management
Jocelyne Piret et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2011)
Phosphorylation of antiviral and endogenous nucleotides to di- and triphosphates by guanosine monophosphate kinase
Brian G. Gentry et al.
BIOCHEMICAL PHARMACOLOGY (2011)
Mismatch primer-based PCR reveals that helicase-primase inhibitor resistance mutations pre-exist in herpes simplex virus type 1 clinical isolates and are not induced during incubation with the inhibitor
Soumi Sukla et al.
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY (2010)
ASP2151, a novel helicase-primase inhibitor, possesses antiviral activity against varicella-zoster virus and herpes simplex virus types 1 and 2
Koji Chono et al.
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY (2010)
Aciclovir neurotoxicity is an important side effect of therapy in patients with renal impairment
Mark E. Brady et al.
CLINICAL MEDICINE (2009)
A mutation in helicase motif IV of herpes simplex virus type 1 UL5 that results in reduced growth in vitro and lower virulence in a murine infection model is related to the predicted helicase structure
Subhajit Biswas et al.
JOURNAL OF GENERAL VIROLOGY (2009)
An estimate of the global prevalence and incidence of herpes simplex virus type 2 infection
Katharine J. Looker et al.
BULLETIN OF THE WORLD HEALTH ORGANIZATION (2008)
Efficient reactivation of latent herpes simplex virus from mouse central nervous system tissues
Shih-Heng Chen et al.
JOURNAL OF VIROLOGY (2006)
Herpes simplex encephalitis: Adolescents and adults
Richard J. Whitley
ANTIVIRAL RESEARCH (2006)
Herpes simplex virus thymidine kinase mutations associated with resistance to acyclovir: a site-directed mutagenesis study
E Frobert et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2005)
Characterization of virus isolates by particle-associated nucleic acid PCR
A Stang et al.
JOURNAL OF CLINICAL MICROBIOLOGY (2005)
Agents and strategies in development for improved management of herpes simplex virus infection and disease
G Kleymann
EXPERT OPINION ON INVESTIGATIONAL DRUGS (2005)
Isolation and characterization of herpes simplex virus type 1 resistant to arninothiazolylphenyl-based inhibitors of the viral helicase-primase
M Liuzzi et al.
ANTIVIRAL RESEARCH (2004)
Epidemiology of herpes simplex virus types 1 and 2 in Germany:: what has changed?
S Buxbaum et al.
MEDICAL MICROBIOLOGY AND IMMUNOLOGY (2003)
Herpes simplex virus resistance to antiviral drugs
F Morfin et al.
JOURNAL OF CLINICAL VIROLOGY (2003)
Herpes simplex virus resistance to acyclovir and penciclovir after two decades of antiviral therapy
TH Bacon et al.
CLINICAL MICROBIOLOGY REVIEWS (2003)
Potent in vivo antiviral activity of the herpes simplex virus primase-helicase inhibitor BAY 57-1293
UAK Betz et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2002)
New helicase-primase inhibitors as drug candidates for the treatment of herpes simplex disease
G Kleymann et al.
NATURE MEDICINE (2002)
Herpes simplex virus helicase-primase inhibitors are active in animal models of human disease
JJ Crute et al.
NATURE MEDICINE (2002)