4.7 Article

Antifungal Resistance Trends of Candida auris Clinical Isolates in New York and New Jersey from 2016 to 2020

Journal

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
Volume 66, Issue 3, Pages -

Publisher

AMER SOC MICROBIOLOGY
DOI: 10.1128/aac.02242-21

Keywords

antifungals; Candida auris; minimum inhibitory concentration; epidemiological cutoff

Funding

  1. WC
  2. New York State Department of Health (NYSDOH)
  3. CDC [NU50CK000516]

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Around 55% of U.S. Candida auris clinical cases were reported in New York and New Jersey from 2016 to 2020. Almost all clinical isolates from New York and New Jersey (99.8%) were resistant to fluconazole, and 50% were resistant to amphotericin B. Echinocandin resistance increased from 0% to 4%, and pan-resistance increased from 0 to C. auris clinical isolates, but not in New Jersey, highlighting regional differences.
About 55% of U.S. Candida auris clinical cases were reported from New York and New Jersey from 2016 through 2020. Nearly all New York-New Jersey clinical isolates (99.8%) were fluconazole resistant, and 50% were amphotericin B resistant. Echinocandin resistance increased from 0% to 4% and pan-resistance increased from 0 to C. auris clinical isolates but not for New Jersey, highlighting the regional differences. About 55% of U.S. Candida auris clinical cases were reported from New York and New Jersey from 2016 through 2020. Nearly all New York-New Jersey clinical isolates (99.8%) were fluconazole resistant, and 50% were amphotericin B resistant. Echinocandin resistance increased from 0% to 4% and pan-resistance increased from 0 to C. auris clinical isolates but not for New Jersey, highlighting the regional differences.

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