4.6 Review

Computational Psychiatry Needs Time and Context

Journal

ANNUAL REVIEW OF PSYCHOLOGY
Volume 73, Issue -, Pages 243-270

Publisher

ANNUAL REVIEWS
DOI: 10.1146/annurev-psych-021621-124910

Keywords

computational psychiatry; network approach; state versus trait; domain specificity; temporal dynamics; functional analysis

Funding

  1. National Institute ofMental Health (NIMH) [F32MH123055]
  2. NIMH [P50 MH119467, R01 MH084840-08A]

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The lack of influence of computational psychiatry on routine clinical practice may be due to its neglect of the role of time and context in certain mental health problems. Researchers have developed three heuristics to assess the importance of time and context, and review the advances in this area, including modeling state variation and interpreting differences in context.
Why has computational psychiatry yet to influence routine clinical practice? One reason may be that it has neglected context and temporal dynamics in the models of certain mental health problems. We develop three heuristics for estimating whether time and context are important to a mental health problem: Is it characterized by a core neurobiological mechanism? Does it follow a straightforward natural trajectory? And is intentional mental content peripheral to the problem? For many problems the answers are no, suggesting that modeling time and context is critical. We review computational psychiatry advances toward this end, including modeling state variation, using domain-specific stimuli, and interpreting differences in context. We discuss complementary network and complex systems approaches. Novel methods and unification with adjacent fields may inspire a new generation of computational psychiatry.

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