Journal
ANNALS OF SURGICAL ONCOLOGY
Volume 29, Issue 5, Pages 2735-2738Publisher
SPRINGER
DOI: 10.1245/s10434-021-11276-4
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This article reviews the findings of a randomized clinical trial evaluating adjuvant nivolumab in esophageal or gastroesophageal junction carcinoma. The study suggests that postoperative immunotherapy represents a significant treatment option for these aggressive malignancies.
This ASO perspective reviews the findings of a randomized placebo-controlled, clinical trial evaluating adjuvant nivolumab in esophageal or gastroesophageal junction carcinoma, reported recently by the Checkmate 577 investigators. The use of postoperative immunotherapy represents a significant paradigm shift for managing patients who have had limited evidence-based treatment options after completing neoadjuvant chemoradiation followed by resection for these aggressive malignancies.
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