Journal
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
Volume 61, Issue 4, Pages -Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/anie.202112638
Keywords
Buckybowl; Corannulene; Imidazolium; Fluorescent probe; Mitochondria
Categories
Funding
- Nanyang Technological University
- MOE Tier 1 [RG6/20]
- A*Star SERC [A1983c0028, A20E5c0090]
Ask authors/readers for more resources
By imparting high solubility/hydrophilicity to polycyclic aromatic molecules, breakthroughs have been made in the research field, showing potential for applications in organic electronics.
Polycyclic aromatic molecules are promising functional materials for a wide range of applications, especially in organic electronics. However, their largely hydrophobic nature has impeded further applications. As such, imparting high solubility/hydrophilicity to polycyclic aromatic molecules leads to a breakthrough in this research field. Herein, we report the synthesis of diazapentabenzocorannulenium, a cationic nitrogen-embedded buckybowl bearing a central imidazolium core, by a bottom-up strategy from polycyclic aromatic azomethine ylide. X-ray crystallography analyses have revealed a bowl-shaped molecular structure that is capable of forming charge-segregated one-dimensional columns by bowl-in-bowl packing. In addition to its fluorescence capabilities and high dispersibility in water, the molecule was found to selectively localize in the mitochondria of various tumor cells, showing potential as viable mitochondria-selective fluorescent probes.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available