4.7 Article

Mass spectrometry imaging revealed alterations of lipid metabolites in multicellular tumor spheroids in response to hydroxychloroquine

Related references

Note: Only part of the references are listed.
Article Multidisciplinary Sciences

Airborne fine particulate matter induces cognitive and emotional disorders in offspring mice exposed during pregnancy

Chao Zhao et al.

Summary: The study revealed that gestational exposure to PM2.5 can result in cognitive and emotional disorders in offspring, even if the offspring were not directly exposed to PM2.5. Neurodegeneration in the hippocampus, impairment of placental cytoarchitecture, and reprogramming of lipidome induced by PM2.5 exposure may affect maternal-fetal cross-talk and lead to behavioral disorders in offspring.

SCIENCE BULLETIN (2021)

Article Chemistry, Analytical

A novel binary matrix consisting of graphene oxide and caffeic acid for the analysis of scutellarin and its metabolites in mouse kidney by MALDI imaging

Tao Wang et al.

Summary: The study utilized MALDI-MSI to investigate the distribution and localization of scutellarin and its metabolites in kidney tissues, demonstrating improved detection efficiency and accuracy by using a binary matrix of graphene oxide and caffeic acid. The results successfully mapped the distribution of scutellarin and its metabolites in mouse kidney tissues, showing potential for future developments in kidney tumor therapies.

ANALYST (2021)

Review Pharmacology & Pharmacy

Lipids and cancer: Emerging roles in pathogenesis, diagnosis and therapeutic intervention

Lisa M. Butler et al.

ADVANCED DRUG DELIVERY REVIEWS (2020)

Article Biochemical Research Methods

MALDI-MS Imaging Analysis of Noninflammatory Type III Rotaxane Dendrimers

Tao Wang et al.

JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY (2020)

Article Radiology, Nuclear Medicine & Medical Imaging

Imaging of Tumor Spheroids, Dual-Isotope SPECT, and Autoradiographic Analysis to Assess the Tumor Uptake and Distribution of Different Nanobodies

Irati Beltran Hernandez et al.

MOLECULAR IMAGING AND BIOLOGY (2019)

Article Chemistry, Multidisciplinary

Mapping and Profiling Lipid Distribution in a 3D Model of Breast Cancer Progression

Netta Vidavsky et al.

ACS CENTRAL SCIENCE (2019)

Article Biochemical Research Methods

MALDI-Mass Spectrometry Imaging to Investigate Lipid and Bile Acid Modifications Caused by Lentil Extract Used as a Potential Hypocholesterolemic Treatment

Michele Genangeli et al.

JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY (2019)

Article Biochemical Research Methods

Simultaneous quantitation of hydroxychloroquine and its metabolites in mouse blood and tissues using LC-ESI-MS/MS: An application for pharmacokinetic studies

Yashpal S. Chhonker et al.

JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES (2018)

Article Cell & Tissue Engineering

Three-dimensional tissue culture model of human breast cancer for the evaluation of multidrug resistance

Yanfang Ding et al.

JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE (2018)

Article Medicine, Research & Experimental

Chloroquine and hydroxychloroquine inhibit bladder cancer cell growth by targeting basal autophagy and enhancing apoptosis

Yi-Chia Lin et al.

KAOHSIUNG JOURNAL OF MEDICAL SCIENCES (2017)

Article Biochemical Research Methods

Three-Dimensional Cell Cultures in Drug Discovery and Development

Ye Fang et al.

SLAS DISCOVERY (2017)

Article Biochemistry & Molecular Biology

Lipin proteins and glycerolipid metabolism: Roles at the ER membrane and beyond

Peixiang Zhang et al.

BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2017)

Review Endocrinology & Metabolism

Lipidomics for studying metabolism

Xianlin Han

NATURE REVIEWS ENDOCRINOLOGY (2016)

Review Oncology

Lipid metabolic reprogramming in cancer cells

S. Beloribi-Djefaflia et al.

ONCOGENESIS (2016)

Article Biochemical Research Methods

Distribution study of atorvastatin and its metabolites in rat tissues using combined information from UHPLC/MS and MALDI-Orbitrap-MS imaging

Robert Jirasko et al.

ANALYTICAL AND BIOANALYTICAL CHEMISTRY (2014)

Article Chemistry, Multidisciplinary

Opportunities and challenges for use of tumor spheroids as models to test drug delivery and efficacy

Geeta Mehta et al.

JOURNAL OF CONTROLLED RELEASE (2012)

Article Chemistry, Analytical

Imaging Mass Spectrometry of Three-Dimensional Cell Culture Systems

Haohang Li et al.

ANALYTICAL CHEMISTRY (2011)

Review Chemistry, Multidisciplinary

Magnetic Resonance Spectroscopy in Metabolic and Molecular Imaging and Diagnosis of Cancer

Kristine Glunde et al.

CHEMICAL REVIEWS (2010)

Article Radiology, Nuclear Medicine & Medical Imaging

Microscopic images of intraspheroidal pH by 1H magnetic resonance chemical shift imaging of pH sensitive indicators

J Alvarez-Pérez et al.

MAGNETIC RESONANCE MATERIALS IN PHYSICS BIOLOGY AND MEDICINE (2005)

Review Oncology

Targeting ceramide metabolism - a strategy for overcoming drug resistance

A Sanchenkov et al.

JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2001)