Journal
ANAIS DA ACADEMIA BRASILEIRA DE CIENCIAS
Volume 94, Issue 1, Pages -Publisher
ACAD BRASILEIRA DE CIENCIAS
DOI: 10.1590/0001-3765202220201844
Keywords
Banisteriopsis laevifolia; phenolic compounds; antioxidant activity; molecular networking; dereplication
Categories
Funding
- Conselho Nacional de Desenvolvimento Cientifico e Tecnologico (CNPq) [422513/2016-4]
- CNPq [315276/2018-5]
Ask authors/readers for more resources
This study identified and characterized compounds from the ethanolic extracts of the leaves and flowers of Banisteriopsis using advanced methodologies. The use of Global Natural Products Social Molecular Networking helped identify seven compounds reported for the first time in this species. The presence and synergistic effect of compounds may contribute to the observed antioxidant activity, warranting further investigation into the chemical and biological properties of these species.
The genus Banisteriopsis (Malpighiaceae) comprises 77 genera and 1,300 species. Despite efforts to provide detailed information about the chemical wealth of B. laevifolia, this article provides the identification and characterization of compounds from the ethanolic extracts of the leaves and flowers using advanced methodologies which include high-performance liquid chromatography coupled to tandem mass spectrometry, which contribute to the knowledge about compounds present in the genus Banisteriopsis. The dereplication aided by Global Natural Products Social Molecular Networking afforded the identification of seven compounds reported for this species for the first time. A mixture of two known flavonoids and a diterpenoid, 18-hydroxy-ent-halima-1(10),13-(E)-dien-15-oic acid, were isolated by conventional separation methods. The elevated 2,2-di phenyl-1-picrythydrazyl radical scavenging activity observed in some samples was attributed to either the type of extract, the presence of 3,4,5-trihydroxybenzoic acid, or the influence of the substitution pattern and the synergistic effect of the compounds present. Principal Component Analysis was applied to correlate mass spectrometry data with the antioxidant activity of the samples. The high diversity of metabolites found in this study and those which have been reported for Banisteriopsis strongly recommends further investigation into the chemical and biological properties of these species.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available