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Delirium and COVID-19: a narrative review of emerging evidence

Journal

ANAESTHESIA
Volume 77, Issue -, Pages 49-58

Publisher

WILEY
DOI: 10.1111/anae.15627

Keywords

acute encephalopathy; COVID-19; delirium; inflammation

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Delirium is common in COVID-19 patients and has similar short-term outcomes as classical delirium. Practical management includes screening, identification, and treatment to minimize complications and make timely decisions.
Delirium is a common condition affecting hospital inpatients, including those having surgery and on the intensive care unit. Delirium is also common in patients with COVID-19 in hospital settings, and the occurrence is higher than expected for similar infections. The short-term outcomes of those with COVID-19 delirium are similar to that of classical delirium and include increased length of stay and increased mortality. Management of delirium in COVID-19 in the context of a global pandemic is limited by the severity of the syndrome and compounded by the environmental constraints. Practical management includes effective screening, early identification and appropriate treatment aimed at minimising complications and timely escalation decisions. The pandemic has played out on the national stage and the effect of delirium on patients, relatives and healthcare workers remains unknown but evidence from the previous SARS outbreak suggests there may be long-lasting psychological damage.

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