Biodegradable Polymer with Effective Near-Infrared-II Absorption as a Photothermal Agent for Deep Tumor Therapy

Photothermal therapy holds great promise for cancer treatment due to its effective tumor ablation and minimal invasiveness. Herein a new class of biodegradable photothermal agents with effective adsorption in both near-infrared-I (NIR-I) and NIR-II windows is reported for deep tumor therapy. As demonstrated in a deep-seated ovarian cancer model, photothermal therapy using 1064 nm irradiation effectively inhibits tumor progression and prolongs survival spans. This work provides a new design of photothermal agents toward a more effective therapy of tumors.

Automated summary

Photothermal therapy shows great potential for cancer treatment due to its effective tumor ablation and minimal invasiveness. This study introduces a new class of biodegradable photothermal agents that effectively absorb near-infrared light for deep tumor therapy, demonstrating successful results in a deep-seated ovarian cancer model. This work paves the way for the design of more effective photothermal agents.