THERAPEUTIC USE OF SINGLET OXYGEN FOR BREAST CANCER EX VIVO

The incidence and mortality from breast cancer in society is increasing. For early detection of breast cancer, it is recommended to perform ultrasound and mammography, and magnetic resonance imaging. This article is a review of recent advances in photodynamic therapy for the treatment of breast cancer. Photodynamic therapy (PDT) is a novel cancer diagnostic and cancer treatment therapy. This method uses light, oxygen, and photosensitizers to generate cytotoxic reactive oxygen species. PDT is often used on the surface of the skin or mucous membranes and there are few reports of this methodology for the treatment of breast cancer. The knowledge gained from preclinical photodynamic therapy in vitro can be useful for the development of biomedical applications in vivo.

Automated summary

The incidence and mortality of breast cancer are on the rise in society. Early detection through ultrasound, mammography, and MRI are recommended. Photodynamic therapy (PDT) is a novel approach used for both cancer diagnosis and treatment, utilizing light, oxygen, and photosensitizers to generate cytotoxic reactive oxygen species for cancer treatment, though its application in breast cancer remains limited. Preclinical studies on PDT can provide useful insights for its biomedical applications in vivo.