4.8 Review

Wound Dressing: From Nanomaterials to Diagnostic Dressings and Healing Evaluations

Journal

ACS NANO
Volume 16, Issue 2, Pages 1708-1733

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/acsnano.1c08411

Keywords

wound; dressing; nanomaterial; healing; sensor; diagnostics; monitoring; therapeutics

Funding

  1. National Natural Science Foundation of China [21775044, 21635003]
  2. Shanghai Science and Technology Committee [19ZR1473300, 18DZ1112700]
  3. Fundamental Research Funds for the Central Universities

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This article reviews the importance of wound dressings based on nanomaterials in wound treatment and highlights their functional advantages and smart development trends. It also explores the challenges and opportunities associated with nanomaterial-based wound dressings in clinical practice.
Wound dressings based on nanomaterials play a crucial role in wound treatment and are widely used in a whole range of medical settings, from minor to life-threatening tissue injuries. This article presents an educational review on the accumulating knowledge in this multidisciplinary area to lay out the challenges and opportunities that lie ahead and ignite the further and faster development of clinically valuable technologies. The review analyzes the functional advantages of nanomaterial-based gauzes and hydrogels as well as hybrid structures thereof. On this basis, the review presents state-of-the-art advances to transfer the (semi)blind approaches to the evaluation of a wound state to smart wound dressings that enable real-time monitoring and diagnostic functions that could help in wound evaluation during healing. This review explores the translation of nanomaterial-based wound dressings and related medical aspects into real-world use. The ongoing challenges and future opportunities associated with nanomaterial-based wound dressings and related clinical decisions are presented and reviewed.

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