4.6 Article

Distinct Dibasic Cleavage Specificities of Neuropeptide-Producing Cathepsin L and Cathepsin V Cysteine Proteases Compared to PC1/3 and PC2 Serine Proteases

Related references

Note: Only part of the references are listed.
Article Biochemistry & Molecular Biology

Differential Neuropeptidomes of Dense Core Secretory Vesicles (DCSV) Produced at Intravesicular and Extracellular pH Conditions by Proteolytic Processing

Zhenze Jiang et al.

Summary: This study investigated the production of neuropeptides within cells at different pH conditions and found that distinct neuropeptidomes are generated at internal and external pH levels. Various types of proteases play a role in regulating neuropeptide formation.

ACS CHEMICAL NEUROSCIENCE (2021)

Article Biochemical Research Methods

Diversity of Neuropeptide Cell-Cell Signaling Molecules Generated by Proteolytic Processing Revealed by Neuropeptidomics Mass Spectrometry

Vivian Hook et al.

JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY (2018)

Review Biochemistry & Molecular Biology

The CRF Family of Neuropeptides and their Receptors - Mediators of the Central Stress Response

Nina Dedic et al.

CURRENT MOLECULAR PHARMACOLOGY (2018)

Article Biochemistry & Molecular Biology

Cardiac procholecystokinin expression during haemodynamic changes in the mammalian heart

Jens P. Goetze et al.

PEPTIDES (2018)

Article Medicine, Research & Experimental

Deficiency in prohormone convertase PC1 impairs prohormone processing in Prader-Willi syndrome

Lisa C. Burnett et al.

JOURNAL OF CLINICAL INVESTIGATION (2017)

Review Endocrinology & Metabolism

Insulin and Glucagon: Partners for Life

Jens Juul Holst et al.

ENDOCRINOLOGY (2017)

Review Pharmacology & Pharmacy

The Emerging Role of Spinal Dynorphin in Chronic Pain: A Therapeutic Perspective

Sonia Podvin et al.

ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY, VOL 56 (2016)

Article Multidisciplinary Sciences

ATP: The crucial component of secretory vesicles

Judith Estevez-Herrera et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)

Review Endocrinology & Metabolism

Dual-hormone treatment with insulin and glucagon in patients with type 1 diabetes

H. K. Reiband et al.

DIABETES-METABOLISM RESEARCH AND REVIEWS (2015)

Review Biochemistry & Molecular Biology

The Multifaceted Proprotein Convertases: Their Unique, Redundant, Complementary, and Opposite Functions

Nabil G. Seidah et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2013)

Article Biochemistry & Molecular Biology

Human Cathepsin V Protease Participates in Production of Enkephalin and NPY Neuropeptide Neurotransmitters

Lydiane Funkelstein et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2012)

Article Biochemical Research Methods

Global identification of peptidase specificity by multiplex substrate profiling

Anthony J. O'Donoghue et al.

NATURE METHODS (2012)

Article Medicine, Research & Experimental

Specialized roles for cysteine cathepsins in health and disease

Jochen Reiser et al.

JOURNAL OF CLINICAL INVESTIGATION (2010)

Article Biochemistry & Molecular Biology

Neuropeptidomic analysis establishes a major role for prohormone convertase-2 in neuropeptide biosynthesis

Xin Zhang et al.

JOURNAL OF NEUROCHEMISTRY (2010)

Letter Biochemical Research Methods

Improved visualization of protein consensus sequences by iceLogo

Niklaas Colaert et al.

NATURE METHODS (2009)

Review Pharmacology & Pharmacy

Proteases for processing proneuropeptides into peptide neurotransmitters and hormones

Vivian Hook et al.

ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY (2008)

Review Physiology

Dense-core secretory granule biogenesis

T Kim et al.

PHYSIOLOGY (2006)

Article Multidisciplinary Sciences

Cathepsin L in secretory vesicles functions as a prohormone-processing enzyme for production of the enkephalin peptide neurotransmitter

S Yasothornsrikul et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)

Article Biochemistry & Molecular Biology

Obliteration of α-melanocyte-stimulating hormone derived from POMC in pituitary and brains of PC2-deficient mice

R Miller et al.

JOURNAL OF NEUROCHEMISTRY (2003)

Article Anesthesiology

Clinical pharmacology of opioids for pain

CE Inturrisi

CLINICAL JOURNAL OF PAIN (2002)

Article Multidisciplinary Sciences

Galanin transgenic mice display cognitive and neurochemical deficits characteristic of Alzheimer's disease

RA Steiner et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)

Article Biochemistry & Molecular Biology

Defective prodynorphin processing in mice lacking prohormone convertase PC2

Y Berman et al.

JOURNAL OF NEUROCHEMISTRY (2000)