Related references
Note: Only part of the references are listed.Stress granule formation, disassembly, and composition are regulated by alphavirus ADP-ribosylhydrolase activity
Aravinth Kumar Jayabalan et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2021)
Unique Mutations in the Murine Hepatitis Virus Macrodomain Differentially Attenuate Virus Replication, Indicating Multiple Roles for the Macrodomain in Coronavirus Replication
Lynden S. Voth et al.
JOURNAL OF VIROLOGY (2021)
Fragment binding to the Nsp3 macrodomain of SARS-CoV-2 identified through crystallographic screening and computational docking
Marion Schuller et al.
SCIENCE ADVANCES (2021)
Exploring protein hotspots by optimized fragment pharmacophores
David Bajusz et al.
NATURE COMMUNICATIONS (2021)
The SARS-CoV-2 Conserved Macrodomain Is a Mono-ADP-Ribosylhydrolase
Yousef M. O. Alhammad et al.
JOURNAL OF VIROLOGY (2021)
Both ADP-Ribosyl-Binding and Hydrolase Activities of the Alphavirus nsP3 Macrodomain Affect Neurovirulence in Mice
Rachy Abraham et al.
MBIO (2020)
The species Severe acute respiratory syndrome-related coronavirus: classifying 2019-nCoV and naming it SARS-CoV-2
Alexander E. Gorbalenya et al.
NATURE MICROBIOLOGY (2020)
Molecular Basis for ADP-Ribose Binding to the Mac1 Domain of SARS-CoV-2 nsp3
David N. Frick et al.
BIOCHEMISTRY (2020)
Drug Discovery Strategies for SARS-CoV-2
Zeenat A. Shyr et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2020)
Structural, Biophysical, and Biochemical Elucidation of the SARS-CoV-2 Nonstructural Protein 3 Macro Domain
Meng-Hsuan Lin et al.
ACS INFECTIOUS DISEASES (2020)
Discovery of Drug-Like Ligands for the Mac1 Domain of SARS-CoV-2 Nsp3
Rajdeep S. Virdi et al.
SLAS DISCOVERY (2020)
Viral macrodomains: a structural and evolutionary assessment of the pharmacological potential
Johannes Gregor Matthias Rack et al.
OPEN BIOLOGY (2020)
Viral Macrodomains: Unique Mediators of Viral Replication and Pathogenesis
Anthony R. Fehr et al.
TRENDS IN MICROBIOLOGY (2018)
Macrodomain ADP-ribosylhydrolase and the pathogenesis of infectious diseases
Anthony K. L. Leung et al.
PLOS PATHOGENS (2018)
ADP-ribosyl-binding and hydrolase activities of the alphavirus nsP3 macrodomain are critical for initiation of virus replication
Rachy Abraham et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)
ADP-ribosylhydrolase activity of Chikungunya virus macrodomain is critical for virus replication and virulence
Robert Lyle McPherson et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)
The conserved macrodomains of the non-structural proteins of Chikungunya virus and other pathogenic positive strand RNA viruses function as mono-ADP-ribosylhydrolases
Laura Eckei et al.
SCIENTIFIC REPORTS (2017)
Macrodomains: Structure, Function, Evolution, and Catalytic Activities
Johannes Gregor Matthias Rack et al.
ANNUAL REVIEW OF BIOCHEMISTRY, VOL 85 (2016)
Macro Domain from Middle East Respiratory Syndrome Coronavirus (MERS-CoV) Is an Efficient ADP-ribose Binding Module: CRYSTAL STRUCTURE AND BIOCHEMICAL STUDIES
Chao-Cheng Cho et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2016)
Viral Macro Domains Reverse Protein ADP-Ribosylation
Changqing Li et al.
JOURNAL OF VIROLOGY (2016)
The Conserved Coronavirus Macrodomain Promotes Virulence and Suppresses the Innate Immune Response during Severe Acute Respiratory Syndrome Coronavirus Infection
Anthony R. Fehr et al.
MBIO (2016)
Proximal ADP-ribose Hydrolysis in Trypanosomatids is Catalyzed by a Macrodomain
Teemu Haikarainen et al.
SCIENTIFIC REPORTS (2016)
Nudix hydrolases degrade protein-conjugated ADP-ribose
Casey M. Daniels et al.
SCIENTIFIC REPORTS (2015)
Repurposing of Clinically Developed Drugs for Treatment of Middle East Respiratory Syndrome Coronavirus Infection
Julie Dyall et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2014)
Macrodomain-containing proteins are new mono-ADP-ribosylhydrolases
Florian Rosenthal et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2013)
A family of macrodomain proteins reverses cellular mono-ADP-ribosylation
Gytis Jankevicius et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2013)
New Substructure Filters for Removal of Pan Assay Interference Compounds (PAINS) from Screening Libraries and for Their Exclusion in Bioassays
Jonathan B. Baell et al.
JOURNAL OF MEDICINAL CHEMISTRY (2010)
Mouse Hepatitis Virus Liver Pathology Is Dependent on ADP-Ribose-1-Phosphatase, a Viral Function Conserved in the Alpha-Like Supergroup
Klara Kristin Eriksson et al.
JOURNAL OF VIROLOGY (2008)
Dasatinib induces notable hematologic and cytogenetic responses in chronic-phase chronic myeloid leukemia after failure of imatinib therapy
Andreas Hochhaus et al.
BLOOD (2007)