Related references
Note: Only part of the references are listed.Identification of Potent Reverse Indazole Inhibitors for HPK1
Elsie C. Yu et al.
ACS MEDICINAL CHEMISTRY LETTERS (2021)
Discovery of Orally Active Isofuranones as Potent, Selective Inhibitors of Hematopoetic Progenitor Kinase 1
Andrew P. Degnan et al.
ACS MEDICINAL CHEMISTRY LETTERS (2021)
Discovery of Diaminopyrimidine Carboxamide HPK1 Inhibitors as Preclinical Immunotherapy Tool Compounds
Brandon A. Vara et al.
ACS MEDICINAL CHEMISTRY LETTERS (2021)
Hematopoietic Progenitor Kinase1 (HPK1) Mediates T Cell Dysfunction and Is a Druggable Target for T Cell-Based Immunotherapies
Jingwen Si et al.
CANCER CELL (2020)
MAP4K4 Inhibition Promotes Survival of Human Stem Cell-Derived Cardiomyocytes and Reduces Infarct Size In Vivo
Lorna R. Fiedler et al.
CELL STEM CELL (2019)
Hematopoietic Progenitor Kinase-1 Structure in a Domain-Swapped Dimer
Ping Wu et al.
STRUCTURE (2019)
The Kinase Activity of Hematopoietic Progenitor Kinase 1 Is Essential for the Regulation of T Cell Function
Sairy Hernandez et al.
CELL REPORTS (2018)
Germinal-center kinase-like kinase co-crystal structure reveals a swapped activation loop and C-terminal extension
Douglas Marcotte et al.
PROTEIN SCIENCE (2017)
The target landscape of clinical kinase drugs
Susan Klaeger et al.
SCIENCE (2017)
Domain-Swapping Switch Point in Ste20 Protein Kinase SPAK
Clinton A. Taylor et al.
BIOCHEMISTRY (2015)
Optimized Chemical Proteomics Assay for Kinase Inhibitor Profiling
Guillaume Medard et al.
JOURNAL OF PROTEOME RESEARCH (2015)
Big opportunities for small molecules in immuno-oncology
Jerry L. Adams et al.
NATURE REVIEWS DRUG DISCOVERY (2015)
HGK/MAP4K4 deficiency induces TRAF2 stabilization and Th17 differentiation leading to insulin resistance
Huai-Chia Chuang et al.
NATURE COMMUNICATIONS (2014)
HPK1 as a novel target for cancer immunotherapy
Sansana Sawasdikosol et al.
IMMUNOLOGIC RESEARCH (2012)
Data processing and analysis with the autoPROC toolbox
Clemens Vonrhein et al.
ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2011)
Release of serine/threonine-phosphorylated adaptors from signaling microclusters down-regulates T cell activation
Remi Lasserre et al.
JOURNAL OF CELL BIOLOGY (2011)
The kinase GLK controls autoimmunity and NF-κB signaling by activating the kinase PKC-θ in T cells
Huai-Chia Chuang et al.
NATURE IMMUNOLOGY (2011)
Features and development of Coot
P. Emsley et al.
ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY (2010)
Hematopoietic progenitor kinase 1 is a critical component of prostaglandin E2-mediated suppression of the anti-tumor immune response
Saba Alzabin et al.
CANCER IMMUNOLOGY IMMUNOTHERAPY (2010)
Hematopoietic Progenitor Kinase 1 Is a Negative Regulator of Dendritic Cell Activation
Saba Alzabin et al.
JOURNAL OF IMMUNOLOGY (2009)
Caspase-cleaved HPK1 induces CD95L-independent activation-induced cell death in T and B lymphocytes
Dirk Brenner et al.
BLOOD (2007)
Prostaglandin E2 activates HPK1 kinase activity via a PKA-dependent pathway
Sansana Sawasdikosol et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Substrate and docking interactions in serine/threonine protein kinases
Elizabeth J. Goldsmith et al.
CHEMICAL REVIEWS (2007)
Quantitative chemical proteomics reveals mechanisms of action of clinical ABL kinase inhibitors
Marcus Bantscheff et al.
NATURE BIOTECHNOLOGY (2007)
Phaser crystallographic software
Airlie J. McCoy et al.
JOURNAL OF APPLIED CRYSTALLOGRAPHY (2007)
Hematopoietic progenitor kinase 1 negatively regulates T cell receptor signaling and T cell-mediated immune responses
Jr-Wen Shui et al.
NATURE IMMUNOLOGY (2007)
Functional interactions of HPK1 with adaptor proteins
JS Boomer et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2005)
Hematopoietic progenitor kinase 1 (HPK1) negatively regulates prostaglandin E2-induced fos gene transcription
S Sawasdikosol et al.
BLOOD (2003)
Hematopoietic progenitor kinase 1 supports apoptosis of T lymphocytes
J Schulze-Luehrmann et al.
BLOOD (2002)
Involvement of hematopoietic progenitor kinase 1 in T cell receptor signaling
P Ling et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Share Paper
