Journal
HYPERTENSION IN PREGNANCY
Volume 35, Issue 3, Pages 361-370Publisher
TAYLOR & FRANCIS INC
DOI: 10.3109/10641955.2016.1150488
Keywords
Cord insertion; morphometrics; placenta; preeclampsia; pregnancy
Funding
- College of Health Sciences (University of KwaZulu-Natal)
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Objective: To assess the umbilical cord centrality, placental morphometrics, and functional efficiency in preeclampsia. Methods: Placental morphometry of normotensive (n = 69) and preeclamptic (n = 69) patients was evaluated. Results: There was a significant reduction in mean placental surface area (p = 0.0001), length (p = 0.0001), thickness (p = 0.016), and volume (p = 0.0001) in the preeclamptic than in the normotensive groups. Umbilical cord insertion was predominantly eccentric with marginal in early (29%) and late-onset preeclampsia (16%). Placental and birth weight was lower (p = 0.0001) in preeclampsia than in the normotensive group. Placental efficiency was reduced in early-onset preeclampsia. Conclusion: This study demonstrates reduced placental morphometrics with impaired placental efficiency in preeclampsia.
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