Related references
Note: Only part of the references are listed.Targeting Hsp90/Hsp70-Based Protein Quality Control for Treatment of Adult Onset Neurodegenerative Diseases
William B. Pratt et al.
ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY, VOL 55 (2015)
Proteasome-Mediated Processing of Nrf1 Is Essential for Coordinate Induction of All Proteasome Subunits and p97
Zhe Sha et al.
CURRENT BIOLOGY (2014)
Sulforaphane enhances proteasomal and autophagic activities in mice and is a potential therapeutic reagent for Huntington's disease
Yanying Liu et al.
JOURNAL OF NEUROCHEMISTRY (2014)
Early onset and novel features in a spinal and bulbar muscular atrophy patient with a 68 CAG repeat
Christopher Grunseich et al.
NEUROMUSCULAR DISORDERS (2014)
Curcumin as a Therapeutic Agent in Dementia: A Mini Systematic Review of Human Studies
Natascia Brondino et al.
SCIENTIFIC WORLD JOURNAL (2014)
p97-dependent retrotranslocation and proteolytic processing govern formation of active Nrf1 upon proteasome inhibition
Senthil K. Radhakrishnan et al.
ELIFE (2014)
Co-induction of the heat shock response ameliorates disease progression in a mouse model of human spinal and bulbar muscular atrophy: implications for therapy
Bilal Malik et al.
BRAIN (2013)
Heat Shock Response Activation Exacerbates Inclusion Body Formation in a Cellular Model of Huntington Disease
Kirill Bersuker et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
Activation of Hsp70 reduces neurotoxicity by promoting polyglutamine protein degradation
Adrienne M. Wang et al.
NATURE CHEMICAL BIOLOGY (2013)
Impaired Mitochondrial Dynamics and Nrf2 Signaling Contribute to Compromised Responses to Oxidative Stress in Striatal Cells Expressing Full-Length Mutant Huntingtin
Youngnam N. Jin et al.
PLOS ONE (2013)
Heat shock factor-1 influences pathological lesion distribution of polyglutamine-induced neurodegeneration
Naohide Kondo et al.
NATURE COMMUNICATIONS (2013)
Insulin like Growth Factor (IGF)-1 Administration Ameliorates Disease Manifestations in a Mouse Model of Spinal and Bulbar Muscular Atrophy
Carlo Rinaldi et al.
MOLECULAR MEDICINE (2012)
RPN-6 determines C. elegans longevity under proteotoxic stress conditions
David Vilchez et al.
NATURE (2012)
Experimental demonstration of a universally valid error-disturbance uncertainty relation in spin measurements
Jacqueline Erhart et al.
NATURE PHYSICS (2012)
Genetic activation of Nrf2 signaling is sufficient to ameliorate neurodegenerative phenotypes in a Drosophila model of Parkinson's disease
Maria Cecilia Barone et al.
DISEASE MODELS & MECHANISMS (2011)
Basic Leucine Zipper Protein Cnc-C Is a Substrate and Transcriptional Regulator of the Drosophila 26S Proteasome
Kristian Bjork Grimberg et al.
MOLECULAR AND CELLULAR BIOLOGY (2011)
Amyloid-binding compounds maintain protein homeostasis during ageing and extend lifespan
Silvestre Alavez et al.
NATURE (2011)
Efficacy of Fumaric Acid Esters in the R6/2 and YAC128 Models of Huntington's Disease
Gisa Ellrichmann et al.
PLOS ONE (2011)
Transcription Factor Nrf1 Mediates the Proteasome Recovery Pathway after Proteasome Inhibition in Mammalian Cells
Senthil K. Radhakrishnan et al.
MOLECULAR CELL (2010)
Enhancement of proteasome activity by a small-molecule inhibitor of USP14
Byung-Hoon Lee et al.
NATURE (2010)
Native Functions of the Androgen Receptor Are Essential to Pathogenesis in a Drosophila Model of Spinobulbar Muscular Atrophy
Natalia B. Nedelsky et al.
NEURON (2010)
Altered RNA splicing contributes to skeletal muscle pathology in Kennedy disease knock-in mice
Zhigang Yu et al.
DISEASE MODELS & MECHANISMS (2009)
17-DMAG ameliorates polyglutamine-mediated motor neuron degeneration through well-preserved proteasome function in an SBMA model mouse
Keisuke Tokui et al.
HUMAN MOLECULAR GENETICS (2009)
Mitochondrial abnormalities in spinal and bulbar muscular atrophy
Srikanth Ranganathan et al.
HUMAN MOLECULAR GENETICS (2009)
Overexpression of IGF-1 in Muscle Attenuates Disease in a Mouse Model of Spinal and Bulbar Muscular Atrophy
Isabella Palazzolo et al.
NEURON (2009)
Proteasomes cleave at multiple sites within polyglutamine tracts -: Activation by PA28γ(K188E)
Gregory Pratt et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Nrf2 Activation in Astrocytes Protects against Neurodegeneration in Mouse Models of Familial Amyotrophic Lateral Sclerosis
Marcelo R. Vargas et al.
JOURNAL OF NEUROSCIENCE (2008)
Adapting proteostasis for disease intervention
William E. Balch et al.
SCIENCE (2008)
Vacuolar Leukoencephalopathy with widespread astrogliosis in mice lacking transcription factor Nrf2
Ann F. Hubbs et al.
AMERICAN JOURNAL OF PATHOLOGY (2007)
ASC-J9 ameliorates spinal and bulbar muscular atrophy phenotype via degradation of androgen receptor
Zhiming Yang et al.
NATURE MEDICINE (2007)
Reversible disruption of dynactin 1-mediated retrograde axonal transport in polyglutamine-induced motor neuron degeneration
Masahisa Katsuno et al.
JOURNAL OF NEUROSCIENCE (2006)
Negative regulation of the Nrf1 transcription factor by its N-terminal domain is independent of Keap1: Nrf1, but not Nrf2, is targeted to the endoplasmic reticulum
Yiguo Zhang et al.
BIOCHEMICAL JOURNAL (2006)
Pharmacological induction of heat-shock proteins alleviates polyglutamine-mediated motor neuron disease
M Katsuno et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
17-AAG, an Hsp90 inhibitor, ameliorates polyglutamine-mediated motor neuron degeneration
M Waza et al.
NATURE MEDICINE (2005)
Eukaryotic proteasomes cannot digest polyglutamine sequences and release them during degradation of polyglutamine-containing proteins
P Venkatraman et al.
MOLECULAR CELL (2004)
Antitumor agents. 217. Curcumin analogues as novel androgen receptor antagonists with potential as anti-prostate cancer agents
H Ohtsu et al.
JOURNAL OF MEDICINAL CHEMISTRY (2002)
Testosterone reduction prevents phenotypic expression in a transgenic mouse model of spinal and bulbar muscular atrophy
M Katsuno et al.
NEURON (2002)
Altered transcriptional regulation in cells expressing the expanded polyglutamine androgen receptor
AP Lieberman et al.
HUMAN MOLECULAR GENETICS (2002)
Heat shock protein 27 prevents cellular polyglutamine toxicity and suppresses the increase of reactive oxygen species caused by huntingtin
A Wyttenbach et al.
HUMAN MOLECULAR GENETICS (2002)
Molecular chaperones enhance the degradation of expanded polyglutamine repeat androgen receptor in a cellular model of spinal and bulbar muscular atrophy
CK Bailey et al.
HUMAN MOLECULAR GENETICS (2002)
Geldanamycin activates a heat shock response and inhibits huntingtin aggregation in a cell culture model of Huntington's disease
A Sittler et al.
HUMAN MOLECULAR GENETICS (2001)
Roles of the heat shock transcription factors in regulation of the heat shock response and beyond
L Pirkkala et al.
FASEB JOURNAL (2001)
Chaperones Hsp70 and Hsp40 suppress aggregate formation and apoptosis in cultured neuronal cells expressing truncated androgen receptor protein with expanded polyglutamine tract
Y Kobayashi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Share Paper
