4.0 Article

An overview of basic molecular biology of SARS-CoV-2 and current COVID-19 prevention strategies

Related references

Note: Only part of the references are listed.
Letter Infectious Diseases

Implication of SARS-CoV-2 evolution in the sensitivity of RT-qPCR diagnostic assays

Nuno Sampaio Osorio et al.

LANCET INFECTIOUS DISEASES (2021)

Article Computer Science, Artificial Intelligence

Automatic detection of coronavirus disease (COVID-19) using X-ray images and deep convolutional neural networks

Ali Narin et al.

Summary: The 2019 novel coronavirus disease has rapidly spread worldwide, with nearly 101,917,147 cases reported, leading to a limited availability of COVID-19 test kits in hospitals. To address this, an automatic detection system using pre-trained convolutional neural network-based models was proposed for detecting coronavirus pneumonia-infected patients. Among the five models tested, ResNet50 demonstrated the highest accuracy in classifying COVID-19 patients from X-ray images.

PATTERN ANALYSIS AND APPLICATIONS (2021)

Editorial Material Cell Biology

Virus against virus: a potential treatment for 2019-nCov (SARS-CoV-2) and other RNA viruses

Tuan M. Nguyen et al.

CELL RESEARCH (2020)

Article Infectious Diseases

Detection of 2019 novel coronavirus (2019-nCoV) by real-time RT-PCR

Victor M. Corman et al.

EUROSURVEILLANCE (2020)

Editorial Material Medicine, General & Internal

Coronavirus Infections-More Than Just the Common Cold

Catharine I. Paules et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2020)

Review Immunology

Type III interferons: Balancing tissue tolerance and resistance to pathogen invasion

Achille Broggi et al.

JOURNAL OF EXPERIMENTAL MEDICINE (2020)

Article Virology

Cross-species transmission of the newly identified coronavirus 2019-nCoV

Wei Ji et al.

JOURNAL OF MEDICAL VIROLOGY (2020)

Article Virology

COVID-2019: The role of the nsp2 and nsp3 in its pathogenesis

Silvia Angeletti et al.

JOURNAL OF MEDICAL VIROLOGY (2020)

Article Medicine, General & Internal

Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China

Chaolin Huang et al.

LANCET (2020)

Article Multidisciplinary Sciences

A new coronavirus associated with human respiratory disease in China

Fan Wu et al.

NATURE (2020)

Article Multidisciplinary Sciences

A pneumonia outbreak associated with a new coronavirus of probable bat origin

Peng Zhou et al.

NATURE (2020)

Review Rheumatology

Mechanisms of action of hydroxychloroquine and chloroquine: implications for rheumatology

Eva Schrezenmeier et al.

NATURE REVIEWS RHEUMATOLOGY (2020)

Editorial Material Medicine, General & Internal

Another Decade, Another Coronavirus

Stanley Perlman

NEW ENGLAND JOURNAL OF MEDICINE (2020)

Letter Pharmacology & Pharmacy

Traditional Chinese medicine for COVID-19 treatment

Jun-Ling Ren et al.

PHARMACOLOGICAL RESEARCH (2020)

Editorial Material Radiology, Nuclear Medicine & Medical Imaging

Chest CT Findings in 2019 Novel Coronavirus (2019-nCoV) Infections from Wuhan, China: Key Points for the Radiologist

Jeffrey P. Kanne

RADIOLOGY (2020)

Review Medicine, General & Internal

Diagnostic Testing for Severe Acute Respiratory Syndrome-Related Coronavirus 2 A Narrative Review

Matthew P. Cheng et al.

ANNALS OF INTERNAL MEDICINE (2020)

Article Biochemistry & Molecular Biology

Development of CRISPR as an Antiviral Strategy to Combat SARS-CoV-2 and Influenza

Timothy R. Abbott et al.

Article Biochemistry & Molecular Biology

The Architecture of SARS-CoV-2 Transcriptome

Dongwan Kim et al.

Editorial Material Medicine, General & Internal

The third coronavirus epidemic in the third millennium: what's next?

Rok Civljak et al.

CROATIAN MEDICAL JOURNAL (2020)

Review Infectious Diseases

Review of the 2019 novel coronavirus (SARS-CoV-2) based on current evidence

Lisheng Wang et al.

INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS (2020)

Article Infectious Diseases

Hydroxychloroquine and azithromycin as a treatment of COVID-19: results of an open-label non-randomized clinical trial

Philippe Gautret et al.

INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS (2020)

Review Infectious Diseases

The SARS-CoV-2 outbreak: What we know

Di Wu et al.

INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES (2020)

Article Medicine, Research & Experimental

Clinical and immunological features of severe and moderate coronavirus disease 2019

Guang Chen et al.

JOURNAL OF CLINICAL INVESTIGATION (2020)

Article Biochemistry & Molecular Biology

Crystal structure of Nsp15 endoribonuclease NendoU from SARS-CoV-2

Youngchang Kim et al.

PROTEIN SCIENCE (2020)

Article Multidisciplinary Sciences

Structure of the RNA-dependent RNA polymerase from COVID-19 virus

Yan Gao et al.

SCIENCE (2020)

Article Multidisciplinary Sciences

A human monoclonal antibody blocking SARS-CoV-2 infection

Chunyan Wang et al.

NATURE COMMUNICATIONS (2020)

Editorial Material Critical Care Medicine

Treatment for severe acute respiratory distress syndrome from COVID-19

Michael A. Matthay et al.

LANCET RESPIRATORY MEDICINE (2020)

Article Chemistry, Multidisciplinary

Can Nanotechnology and Materials Science Help the Fight against SARS-CoV-2?

Maria Chiara Sportelli et al.

NANOMATERIALS (2020)

Article Integrative & Complementary Medicine

Traditional Chinese Medicine treatment of COVID-19

Jia Xu et al.

COMPLEMENTARY THERAPIES IN CLINICAL PRACTICE (2020)

Article Public, Environmental & Occupational Health

Presymptomatic Transmission of SARS-CoV-2-Singapore, January 23-March 16, 2020

Wycliffe E. Wei et al.

MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT (2020)

Article Multidisciplinary Sciences

Rapid reconstruction of SARS-CoV-2 using a synthetic genomics platform

Tran Thi Nhu Thao et al.

NATURE (2020)

Article Multidisciplinary Sciences

Aerodynamic analysis of SARS-CoV-2 in two Wuhan hospitals

Yuan Liu et al.

NATURE (2020)

Article Multidisciplinary Sciences

A SARS-CoV-2 protein interaction map reveals targets for drug repurposing

David E. Gordon et al.

NATURE (2020)

Article Multidisciplinary Sciences

Structural basis of receptor recognition by SARS-CoV-2

Jian Shang et al.

NATURE (2020)

Article Biotechnology & Applied Microbiology

CRISPR-Cas12-based detection of SARS-CoV-2

James P. Broughton et al.

NATURE BIOTECHNOLOGY (2020)

Letter Biochemistry & Molecular Biology

The proximal origin of SARS-CoV-2

Kristian G. Andersen et al.

NATURE MEDICINE (2020)

Editorial Material Biotechnology & Applied Microbiology

The COVID-19 vaccine development landscape

Tung Thanh Le et al.

NATURE REVIEWS DRUG DISCOVERY (2020)

Article Biotechnology & Applied Microbiology

Can Stem Cells Beat COVID-19: Advancing Stem Cells and Extracellular Vesicles Toward Mainstream Medicine for Lung Injuries Associated With SARS-CoV-2 Infections

Wojciech Chrzanowski et al.

FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY (2020)

Article Integrative & Complementary Medicine

Homeopathic Clinical Features of 18 Patients in COVID-19 Outbreaks in Hong Kong

Ka Lun Aaron To et al.

HOMEOPATHY (2020)

Article Multidisciplinary Sciences

COVID-19 infection: Origin, transmission, and characteristics of human coronaviruses

Muhammad Adnan Shereen et al.

JOURNAL OF ADVANCED RESEARCH (2020)

Article Multidisciplinary Sciences

Crystal Structure of the SARS-CoV-2 Non-structural Protein 9, Nsp9

Dene R. Littler et al.

ISCIENCE (2020)

Article Pharmacology & Pharmacy

Lianhuaqingwen exerts anti-viral and anti-inflammatory activity against novel coronavirus (SARS-CoV-2)

Li Runfeng et al.

PHARMACOLOGICAL RESEARCH (2020)

Article Biochemistry & Molecular Biology

Architecture and self-assembly of theSARS-CoV-2 nucleocapsid protein

Qiaozhen Ye et al.

PROTEIN SCIENCE (2020)

Article Multidisciplinary Sciences

Distinct conformational states of SARS-CoV-2 spike protein

Yongfei Cai et al.

SCIENCE (2020)

Article Medicine, General & Internal

Phase 1-2 Trial of a SARS-CoV-2 Recombinant Spike Protein Nanoparticle Vaccine

Cheryl Keech et al.

NEW ENGLAND JOURNAL OF MEDICINE (2020)

Article Multidisciplinary Sciences

Inborn errors of type I IFN immunity in patients with life-threatening COVID-19

Qian Zhang et al.

SCIENCE (2020)

Review Biochemistry & Molecular Biology

Structural Characterization of SARS-CoV-2: Where We Are, and Where We Need to Be

Giuseppina Mariano et al.

FRONTIERS IN MOLECULAR BIOSCIENCES (2020)

Article Genetics & Heredity

Genomic characterization of a novel SARS-CoV-2

Rozhgar A. Khailany et al.

GENE REPORTS (2020)

Letter Obstetrics & Gynecology

False-negative testing for severe acute respiratory syndrome coronavirus 2: consideration in obstetrical care

Jeannie C. Kelly et al.

AMERICAN JOURNAL OF OBSTETRICS & GYNECOLOGY MFM (2020)

Article Pharmacology & Pharmacy

Discovering drugs to treat coronavirus disease 2019 (COVID-19)

Liying Dong et al.

DRUG DISCOVERIES AND THERAPEUTICS (2020)

Article Immunology

SARS-CoV-2 nsp13, nsp14, nsp15 and orf6 function as potent interferon antagonists

Chun-Kit Yuen et al.

EMERGING MICROBES & INFECTIONS (2020)

Article Immunology

Attenuated SARS-CoV-2 variants with deletions at the S1/S2 junction

Siu-Ying Lau et al.

EMERGING MICROBES & INFECTIONS (2020)

Article Infectious Diseases

A cautionary tale of false-negative nasopharyngeal COVID-19 testing

Sean S. M. Bullis et al.

IDCASES (2020)

Review Nanoscience & Nanotechnology

Nano-based approach to combat emerging viral (NIPAH virus) infection

Rout George Kerry et al.

NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE (2019)

Article Biochemical Research Methods

SHERLOCK: nucleic acid detection with CRISPR nucleases

Max J. Kellner et al.

NATURE PROTOCOLS (2019)

Article Multidisciplinary Sciences

Durable multitransgene expression in vivo using systemic, nonviral DNA delivery

Chakkrapong Handumrongkul et al.

SCIENCE ADVANCES (2019)

Article Biochemistry & Molecular Biology

Programmable Inhibition and Detection of RNA Viruses Using Cas13

Catherine A. Freije et al.

MOLECULAR CELL (2019)

Review Biochemistry & Molecular Biology

Systems of Delivery of CRISPR/Cas9 Ribonucleoprotein Complexes for Genome Editing

R. N. Amirkhanov et al.

RUSSIAN JOURNAL OF BIOORGANIC CHEMISTRY (2019)

Editorial Material Medicine, Research & Experimental

The interferon paradox: can inhibiting an antiviral mechanism advance an HIV cure?

Steven G. Deeks et al.

JOURNAL OF CLINICAL INVESTIGATION (2017)

Article Multidisciplinary Sciences

Nucleic acid detection with CRISPR-Cas13a/C2c2

Jonathan S. Gootenberg et al.

SCIENCE (2017)

Review Anesthesiology

Lung ultrasound in the critically ill (LUCI): A translational discipline

Daniel Lichtenstein et al.

ANAESTHESIOLOGY INTENSIVE THERAPY (2017)

Article Biotechnology & Applied Microbiology

Detection of Influenza Virus Using Peroxidase-Mimic of Gold Nanoparticles

Syed Rahin Ahmed et al.

BIOTECHNOLOGY AND BIOENGINEERING (2016)

Review Virology

Structure, Function, and Evolution of Coronavirus Spike Proteins

Fang Li

ANNUAL REVIEW OF VIROLOGY, VOL 3 (2016)

Article Multidisciplinary Sciences

Elimination of HIV-1 Genomes from Human T-lymphoid Cells by CRISPR/Cas9 Gene Editing

Rafal Kaminski et al.

SCIENTIFIC REPORTS (2016)

Article Immunology

Severe Acute Respiratory Syndrome Beyond Amoy Gardens: Completing the Incomplete Legacy

Ignatius Tak-Sun Yu et al.

CLINICAL INFECTIOUS DISEASES (2014)

Article Multidisciplinary Sciences

RNA-directed gene editing specifically eradicates latent and prevents new HIV-1 infection

Wenhui Hu et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)

Article Immunology

Gold Nanoparticles as an HIV Entry Inhibitor

S. Vijayakumar et al.

CURRENT HIV RESEARCH (2012)

Article Biochemistry & Molecular Biology

The solution structure of coronaviral stem-loop 2 (SL2) reveals a canonical CUYG tetraloop fold

Chul Won Lee et al.

FEBS LETTERS (2011)

Article Biotechnology & Applied Microbiology

Mode of antiviral action of silver nanoparticles against HIV-1

Humberto H Lara et al.

JOURNAL OF NANOBIOTECHNOLOGY (2010)

Article Multidisciplinary Sciences

Functional screen reveals SARS coronavirus nonstructural protein nsp14 as a novel cap N7 methyltransferase

Yu Chen et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)

Review Medicine, General & Internal

Meta-analysis: Convalescent blood products for Spanish influenza pneumonia: A future H5N1 treatment?

Thomas C. Luke et al.

ANNALS OF INTERNAL MEDICINE (2006)

Article Biochemistry & Molecular Biology

DNA detection using recombination proteins

Olaf Piepenburg et al.

PLOS BIOLOGY (2006)

Article Virology

Chloroquine is a potent inhibitor of SARS coronavirus infection and spread

Martin J. Vincent et al.

VIROLOGY JOURNAL (2005)

Review Microbiology

Molecular biology of severe acute respiratory syndrome coronavirus

J Ziebuhr

CURRENT OPINION IN MICROBIOLOGY (2004)

Article Biochemistry & Molecular Biology

Helicase-dependent isothermal DNA amplification

M Vincent et al.

EMBO REPORTS (2004)

Review Medicine, General & Internal

Severe acute respiratory syndrome (SARS): epidemiology and clinical features

DSC Hui et al.

POSTGRADUATE MEDICAL JOURNAL (2004)

Article Biotechnology & Applied Microbiology

Mechanisms and enzymes involved in SARS coronavirus genome expression

V Thiel et al.

JOURNAL OF GENERAL VIROLOGY (2003)

Article Virology

Early diagnosis of SARS Coronavirus infection by real time RT-PCR

LLM Poon et al.

JOURNAL OF CLINICAL VIROLOGY (2003)

Article Biochemistry & Molecular Biology

Loop-mediated isothermal amplification of DNA

Tsugunori Notomi et al.

NUCLEIC ACIDS RESEARCH (2000)