Journal
HERZ
Volume 41, Issue 4, Pages 331-341Publisher
URBAN & VOGEL
DOI: 10.1007/s00059-015-4371-7
Keywords
Atrial fibrillation; Repeat catheter ablation; Estimated glomerular filtration rate; Renal function; CHA(2)DS(2)-VASc score
Categories
Funding
- National Natural Science Fund of China [81270161, 81370301]
Ask authors/readers for more resources
Renal impairment and atrial fibrillation (AF) often coexist. Catheter ablation is an effective way to reduce the burden of AF and improve symptoms; however, little is known about the relationship between renal function and AF and its role in the progression of AF for patients undergoing repeat catheter ablation. In all, 171 patients with long-standing persistent AF ablation were enrolled in the study. The patients were divided into two groups according to their delta estimated glomerular filtration rate (eGFR) values, which was defined as the eGFR before the repeat procedure minus the eGFR before the initial procedure. Patients with decreasing eGFR (delta eGFR < 0) were categorized as group I, while individuals with no change or increasing eGFR (delta eGFRa parts per thousand yen 0) were categorized as group II. eGFR was estimated at baseline and at the 12-month and 24-month follow-up visits. After a mean follow-up of 31.4 +/- 13.2 months, group I had a significantly higher arrhythmia recurrence rate than group II (71.2 vs. 49.2 %, p < 0.001). On multivariable analyses, eGFR changes after the repeat procedure were associated with arrhythmia recurrence, hypertrophic cardiomyopathy, and CHA(2)DS(2)-VASc score. Patients with arrhythmia recurrence and those with a CHA(2)DS(2)-VASc score of a parts per thousand yen 3 were more likely to show an eGFR decline at follow-up. Patients with long-standing persistent AF, with a failed initial ablation procedure and undergoing a repeat ablation procedure, appear to have a higher risk of arrhythmia recurrence. During the follow-up period, patients without arrhythmia recurrence and those with a CHA(2)DS(2)-VASc score of < 3 show improved renal function.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available