4.8 Review

Bile Acids and Nonalcoholic Fatty Liver Disease: Molecular Insights and Therapeutic Perspectives

Related references

Note: Only part of the references are listed.
Article Gastroenterology & Hepatology

Microbiota-induced obesity requires farnesoid X receptor

Ava Parseus et al.

Article Gastroenterology & Hepatology

Hepatocellular Carcinoma in the Absence of Cirrhosis in United States Veterans Is Associated With Nonalcoholic Fatty Liver Disease

Sahil Mittal et al.

CLINICAL GASTROENTEROLOGY AND HEPATOLOGY (2016)

Article Gastroenterology & Hepatology

Nonalcoholic Fatty Liver Disease and the Gut Microbiome

Jerome Boursier et al.

CLINICS IN LIVER DISEASE (2016)

Article Endocrinology & Metabolism

Effects of obeticholic acid on lipoprotein metabolism in healthy volunteers

R. Pencek et al.

DIABETES OBESITY & METABOLISM (2016)

Review Endocrinology & Metabolism

Therapeutic potential of Takeda-G-protein-receptor-5 (TGR5) agonists. Hope or hype?

R. J. Hodge et al.

DIABETES OBESITY & METABOLISM (2016)

Article Biochemistry & Molecular Biology

Activation of Transmembrane Bile Acid Receptor TGR5 Modulates Pancreatic Islet Cells to Promote Glucose Homeostasis

Divya P. Kumar et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2016)

Article Gastroenterology & Hepatology

Glucagon-like peptide 1 decreases lipotoxicity in non-alcoholic steatohepatitis

Matthew J. Armstrong et al.

JOURNAL OF HEPATOLOGY (2016)

Review Biotechnology & Applied Microbiology

Non-alcoholic steatohepatitis: emerging molecular targets and therapeutic strategies

Giovanni Musso et al.

NATURE REVIEWS DRUG DISCOVERY (2016)

News Item Multidisciplinary Sciences

LIPID BIOLOGY Why high 'good cholesterol' can be bad news

Jennifer Couzin-Frankel

SCIENCE (2016)

Review Gastroenterology & Hepatology

Nuclear Receptor Modulation for the Treatment of Nonalcoholic Fatty Liver Disease

Claudia D. Fuchs et al.

SEMINARS IN LIVER DISEASE (2016)

Review Food Science & Technology

Bile Acid Modifications at the Microbe-Host Interface: Potential for Nutraceutical and Pharmaceutical Interventions in Host Health

Susan A. Joyce et al.

ANNUAL REVIEW OF FOOD SCIENCE AND TECHNOLOGY, VOL 7 (2016)

Article Cell Biology

The Bile Acid Chenodeoxycholic Acid Increases Human Brown Adipose Tissue Activity

Evie P. M. Broeders et al.

CELL METABOLISM (2015)

Article Peripheral Vascular Disease

FXR Agonists as Therapeutic Agents for Non-alcoholic Fatty Liver Disease

Rotonya M. Carr et al.

CURRENT ATHEROSCLEROSIS REPORTS (2015)

Review Biochemistry & Molecular Biology

Mechanisms of enterohepatic fibroblast growth factor 15/19 signaling in health and disease

Daniel Jahn et al.

CYTOKINE & GROWTH FACTOR REVIEWS (2015)

Article Gastroenterology & Hepatology

Bile Acid Signaling: Mechanism for Bariatric Surgery, Cure for NASH?

Rohit Kohli et al.

DIGESTIVE DISEASES (2015)

Review Gastroenterology & Hepatology

Bariatric surgery and nonalcoholic fatty liver disease

Guy Bower et al.

EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY (2015)

Article Gastroenterology & Hepatology

Efficacy of Obeticholic Acid in Patients With Primary Biliary Cirrhosis and Inadequate Response to Ursodeoxycholic Acid

Gideon M. Hirschfield et al.

GASTROENTEROLOGY (2015)

Review Gastroenterology & Hepatology

The gut microbiota of nonalcoholic fatty liver disease: current methods and their interpretation

Niels van Best et al.

HEPATOLOGY INTERNATIONAL (2015)

Article Biochemistry & Molecular Biology

Intestinal FXR agonism promotes adipose tissue browning and reduces obesity and insulin resistance

Sungsoon Fang et al.

NATURE MEDICINE (2015)

Review Gastroenterology & Hepatology

Systemic Complications of Nonalcoholic Fatty Liver Disease: When the Liver Is Not an Innocent Bystander

Ester Vanni et al.

SEMINARS IN LIVER DISEASE (2015)

Review Gastroenterology & Hepatology

The Gut Microbiota and Nonalcoholic Fatty Liver Disease

Eamonn M. Quigley et al.

SEMINARS IN LIVER DISEASE (2015)

Review Gastroenterology & Hepatology

Pharmacotherapy for Nonalcoholic Fatty Liver Disease

Samer Gawrieh et al.

SEMINARS IN LIVER DISEASE (2015)

Review Gastroenterology & Hepatology

Epidemiology and Natural History of Nonalcoholic Fatty Liver Disease

Sanjaya K. Satapathy et al.

SEMINARS IN LIVER DISEASE (2015)

Review Pharmacology & Pharmacy

TGR5 and Immunometabolism: Insights from Physiology and Pharmacology

Alessia Perino et al.

TRENDS IN PHARMACOLOGICAL SCIENCES (2015)

Review Gastroenterology & Hepatology

Genetic background in nonalcoholic fatty liver disease: A comprehensive review

Fabio Salvatore Macaluso et al.

WORLD JOURNAL OF GASTROENTEROLOGY (2015)

Article Multidisciplinary Sciences

Intestine-selective farnesoid X receptor inhibition improves obesity-related metabolic dysfunction

Changtao Jiang et al.

NATURE COMMUNICATIONS (2015)

Article Endocrinology & Metabolism

Bioenergetic cues shift FXR splicing towards FXRα2 to modulate hepatic lipolysis and fatty acid metabolism

Jorge C. Correia et al.

MOLECULAR METABOLISM (2015)

Review Pharmacology & Pharmacy

The human gut sterolbiome: bile acid-microbiome endocrine aspects and therapeutics

Jason M. Ridlon et al.

ACTA PHARMACEUTICA SINICA B (2015)

Review Pharmacology & Pharmacy

Metabolic effects of intestinal absorption and enterohepatic cycling of bile acids

Courtney B. Ferrebee et al.

ACTA PHARMACEUTICA SINICA B (2015)

Review Biochemistry & Molecular Biology

Nuclear bile acid signaling through the farnesoid X receptor

Claire Mazuy et al.

CELLULAR AND MOLECULAR LIFE SCIENCES (2015)

Article Oncology

Ileal FGF15 contributes to fibrosis-associated hepatocellular carcinoma development

Iker Uriarte et al.

INTERNATIONAL JOURNAL OF CANCER (2015)

Article Medicine, Research & Experimental

Intestinal farnesoid X receptor signaling promotes nonalcoholic fatty liver disease

Changtao Jiang et al.

JOURNAL OF CLINICAL INVESTIGATION (2015)

Article Gastroenterology & Hepatology

Bile acid receptors and nonalcoholic fatty liver disease

Liyun Yuan et al.

WORLD JOURNAL OF HEPATOLOGY (2015)

Article Biochemistry & Molecular Biology

Activation of farnesoid X receptor (FXR) protects against fructose-induced liver steatosis via inflammatory inhibition and ADRP reduction

Xijun Liu et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2014)

Article Gastroenterology & Hepatology

The Fatty Acid-Bile Acid Conjugate Aramchol Reduces Liver Fat Content in Patients With Nonalcoholic Fatty Liver Disease

Rifaat Safadi et al.

CLINICAL GASTROENTEROLOGY AND HEPATOLOGY (2014)

Review Gastroenterology & Hepatology

State of the art: treatment of nonalcoholic steatohepatitis

Michelle Pearlman et al.

CURRENT OPINION IN GASTROENTEROLOGY (2014)

Review Gastroenterology & Hepatology

Bile acids and the gut microbiome

Jason M. Ridlon et al.

CURRENT OPINION IN GASTROENTEROLOGY (2014)

Review Gastroenterology & Hepatology

The bile acid TGR5 membrane receptor: From basic research to clinical application

Henri Duboc et al.

DIGESTIVE AND LIVER DISEASE (2014)

Review Gastroenterology & Hepatology

Bile acid receptors as targets for drug development

Frank G. Schaap et al.

NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY (2014)

Article Pharmacology & Pharmacy

Bile acid receptors in non-alcoholic fatty liver disease

Yuanyuan Li et al.

BIOCHEMICAL PHARMACOLOGY (2013)

Article Biochemistry & Molecular Biology

Bile Acid Receptor Activation Modulates Hepatic Monocyte Activity and Improves Nonalcoholic Fatty Liver Disease

Rachel H. McMahan et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2013)

Review Biochemistry & Molecular Biology

Bile acid sequestrants: more than simple resins

Carolien Out et al.

CURRENT OPINION IN LIPIDOLOGY (2012)

Review Chemistry, Medicinal

Patented TGR5 modulators: a review (2006-present)

Antimo Gioiello et al.

EXPERT OPINION ON THERAPEUTIC PATENTS (2012)

Review Health Care Sciences & Services

Selection of the appropriate method for the assessment of insulin resistance

Anwar Borai et al.

BMC MEDICAL RESEARCH METHODOLOGY (2011)

Article Endocrinology & Metabolism

Farnesoid X Receptor Deficiency Improves Glucose Homeostasis in Mouse Models of Obesity

Janne Prawitt et al.

DIABETES (2011)

Article Gastroenterology & Hepatology

Hepatic Overexpression of Abcb11 Promotes Hypercholesterolemia and Obesity in Mice

Anne S. Henkel et al.

GASTROENTEROLOGY (2011)

Article Gastroenterology & Hepatology

Frequency and Outcomes of Liver Transplantation for Nonalcoholic Steatohepatitis in the United States

Michael R. Charlton et al.

GASTROENTEROLOGY (2011)

Article Gastroenterology & Hepatology

Nor-ursodeoxycholic acid reverses hepatocyte-specific nemo-dependent steatohepatitis

Naiara Beraza et al.

Review Gastroenterology & Hepatology

The bile acid membrane receptor TGR5 as an emerging target in metabolism and inflammation

Thijs W. H. Pols et al.

JOURNAL OF HEPATOLOGY (2011)

Article Cardiac & Cardiovascular Systems

Upregulation of scavenger receptor class B type I expression by activation of FXR in hepatocyte

Fan Chao et al.

ATHEROSCLEROSIS (2010)

Review Gastroenterology & Hepatology

Pathology of nonalcoholic fatty liver disease

Elizabeth M. Brunt

NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY (2010)

Article Cell Biology

TGR5-Mediated Bile Acid Sensing Controls Glucose Homeostasis

Charles Thomas et al.

CELL METABOLISM (2009)

Review Gastroenterology & Hepatology

Biology of incretins: GLP-1 and GIP

Laurie L. Baggio et al.

GASTROENTEROLOGY (2007)

Article Multidisciplinary Sciences

Regulation of antibacterial defense in the small intestine by the nuclear bile acid receptor

T Inagaki et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)

Article Multidisciplinary Sciences

Activation of the nuclear receptor FXR improves hyperglycemia and hyperlipidemia in diabetic mice

YQ Zhang et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)

Article Biochemistry & Molecular Biology

Bile acids promote glucagon-like peptide-1 secretion through TGR5 in a murine enteroendocrine cell line STC-1

S Katsuma et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2005)

Article Endocrinology & Metabolism

Regulation of carbohydrate metabolism by the farnesoid X receptor

KR Stayrook et al.

ENDOCRINOLOGY (2005)

Article Biochemistry & Molecular Biology

Hepatic overexpression of murine Abcb11 increases hepatobiliary lipid secretion and reduces hepatic steatosis

A Figge et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2004)

Article Biochemistry & Molecular Biology

Identification of membrane-type receptor for bile acids (M-BAR)

T Maruyama et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2002)

Article Biochemistry & Molecular Biology

Bile acids enhance low density lipoprotein receptor gene expression via a MAPK cascade-mediated stabilization of mRNA

M Nakahara et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2002)