Journal
ANNALS OF MEDICINE AND SURGERY
Volume 69, Issue -, Pages -Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.amsu.2021.102745
Keywords
-
Categories
Ask authors/readers for more resources
COVID-19 pandemic results in high morbidity and mortality, affecting multiple organ systems through various mechanisms. The virus may enter through Angiotensin receptor (ACE) and release pro-inflammatory markers. Predictors of different presentations in affected population remain elusive.
Coronavirus disease-19 (COVID-19) pandemic is associated with high morbidity and mortality. COVID-19, which is caused by the Severe Acute Respiratory Syndrome Coronavirus-2 (SARS CoV-2), affects multiple organ systems through a myriad of mechanisms. Afflicted patients present with a vast constellation of symptoms, from asymptomatic disease to life-threatening complications. The most common manifestations pertain to mild pulmonary symptoms, which can progress to respiratory distress syndrome and venous thromboembolism. However, in patients with renal failure, life-threatening cardiac abnormalities can ensue. Various mechanisms such as viral entry through Angiotensin receptor (ACE) affecting multiple organs and thus releasing pro-inflammatory markers have been postulated. Nevertheless, the predictors of various presentations in the affected population remain elusive. An ameliorated understanding of the pathology and pathogenesis of the viral infection has led to the development of variable treatment options, with many more that are presently under trial. This review article discusses the pathogenesis of multiple organ involvement secondary to COVID-19 infection in infected patients.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available