4.5 Review

Epidemiology and Clinical Outcomes of Metabolic (Dysfunction)-associated Fatty Liver Disease

Related references

Note: Only part of the references are listed.
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Summary: The article discusses the proposal to rename NAFLD to MAFLD, highlighting the shortcomings of the new term and warning that changing the name without a comprehensive understanding may have negative implications for the field. The recommendation is to establish a true international consensus group to assess the impact and consequences of the terminology change and make recommendations based on available evidence to move the field forward.

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Summary: The article discusses the renaming of non-alcoholic fatty liver disease to metabolic-associated fatty liver disease, with patient advocacy groups enthusiastically supporting this change. They believe it will have a positive impact on patient care, quality of life, and reduce burdens on healthcare systems.

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Summary: This study found a high prevalence of fatty liver disease (FLD) among middle-aged Korean adults, with MAFLD having a significantly higher prevalence than NAFLD. Both NAFLD and MAFLD were associated with an increased risk of cardiovascular disease (CVD).

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Summary: The study found that individuals meeting the criteria for MAFLD had more comorbidities and worse prognosis compared to those with NAFLD only. Non-NAFLD MAFLD participants had the highest cumulative incidence of all-cause mortality, followed by NAFLD-MAFLD and non-MAFLD NAFLD participants. The MAFLD criteria should be considered in the general population to identify high-risk groups for early interventions.

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Summary: The Latin American Association for the Study of the Liver aims to promote liver health and quality patient care, with a recent focus on fatty liver disease associated with metabolic dysfunction. A consensus was reached to rename the disease as metabolic-associated fatty liver disease and to diagnose it using a set of simple criteria. This change is expected to improve disease awareness and advancements in various aspects of the disease.

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