4.4 Review

Recent progress in polymer hydrogel bioadhesives

Journal

JOURNAL OF POLYMER SCIENCE
Volume 59, Issue 13, Pages 1312-1337

Publisher

WILEY
DOI: 10.1002/pol.20210249

Keywords

adhesive hydrogel bioadhesives; sensors; tissue adhesives; wound closure

Funding

  1. National Natural Science Foundation of China [51873224]
  2. Ningbo Municipal Bureau of Science and Technology [2018B10040]
  3. Ministry of Industry and Information Technology of China [TC90HZV/1]

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Adhesive hydrogels have wide applications in medicine, including tissue adhesives, hemostatic agents, and biomedical sensors. Medical adhesives and sensors require specific properties to quickly and effectively control bleeding and ensure biological safety. Current research focuses on the structure, adhesion mechanisms, and emerging applications of adhesive hydrogel systems.
Adhesive hydrogels have broad applications in tissue adhesives, hemostatic agents, and biomedical sensors. Various bio-inspired glues and synthetic adhesives are clinically used as conventional hemostatic agents and auxiliary tools for wound closure. Medical adhesives are needed to effectively and quickly control bleeding, thereby reducing the risk of complications caused by severe blood loss. Medical sensors need to have excellent skin compliance, mechanical properties, sensitivity, and biological safety. This review focuses on recent progress in adhesive hydrogel systems, their structures, adhesion mechanisms, construction strategies, and emerging applications in the biomedical field.

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