The effect of low serum calcium level on the severity and mortality of Covid patients: A systematic review and meta-analysis

Article Nutrition & Dietetics

Serum vitamin D, calcium, and zinc levels in patients with COVID-19

Abdolahi Shahvali Elham et al.

Summary: This study found that COVID-19 patients have lower serum levels of vitamin D, calcium, and zinc compared to the control group, suggesting that supplementation with these nutrients may help in coping with the pandemic.

CLINICAL NUTRITION ESPEN (2021)

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Article Nutrition & Dietetics

Vitamin D Deficiency and Low Serum Calcium as Predictors of Poor Prognosis in Patients with Severe COVID-19

Salam Bennouar et al.

Summary: This study found that hypovitaminosis D and hypocalcemia were common in severe COVID-19 patients and were significantly associated with in-hospital mortality. Corrected calcium levels below 2.05 mmol/l and vitamin D levels below 39 nmol/l could predict poor prognosis. The findings suggest that correcting hypocalcemia and supplementing with vitamin D may improve the prognosis of severe COVID-19 patients.

JOURNAL OF THE AMERICAN COLLEGE OF NUTRITION (2021)

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Article Evolutionary Biology

Conflicts over calcium and the treatment of COVID-19

Bernard Crespi et al.

Summary: The use of calcium channel blockers and hypocalcemia have significant effects on the treatment and progression of COVID-19 and other viruses. Research findings suggest that hypocalcemia may represent a host defense mechanism against pathogens.

EVOLUTION MEDICINE AND PUBLIC HEALTH (2021)

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Article Medicine, General & Internal

High Prevalence of Hypocalcemia in Non-severe COVID-19 Patients: A Retrospective Case-Control Study

Rimesh Pal et al.

Summary: The study compared serum calcium and phosphate levels in patients with non-severe COVID-19 to a healthy adult cohort, finding that the patients had significantly lower levels of both calcium and phosphate compared to the controls.

FRONTIERS IN MEDICINE (2021)

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Article Infectious Diseases

Impact of low serum calcium at hospital admission on SARS-CoV-2 infection outcome

Berta Torres et al.

Summary: This study retrospectively analyzed serum calcium levels in hospitalized patients with SARS-CoV-2 infection, finding that patients with hypocalcemia may have a worse outcome, requiring more high oxygen support and being more likely to be admitted to the ICU. More research is needed to understand the role of calcium metabolism in SARS-CoV-2 infection and its implications for clinical interventions.

INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES (2021)

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Article Immunology

Parameters associated with diagnosis of COVID-19 in emergency department

Claudio Ucciferri et al.

Summary: The study identified typical radiological and laboratory characteristics in patients with COVID-19, aiding in differential diagnosis. Analyzing laboratory and radiological parameters can assist clinicians in diagnosing and treating suspected cases of COVID-19.

IMMUNITY INFLAMMATION AND DISEASE (2021)

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Article Infectious Diseases

Serum Calcium and Vitamin D levels: Correlation with severity of COVID-19 in hospitalized patients in Royal Hospital, Oman

Wessam Osman et al.

Summary: Hypocalcemia is correlated with disease severity and progression in COVID-19 patients, while vitamin D levels do not show a significant correlation with the severity of infections. These findings suggest that hypocalcemia may serve as a reliable marker of disease severity regardless of underlying comorbidities.

INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES (2021)

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Article Medicine, General & Internal

Abnormal Coagulation Function of Patients With COVID-19 Is Significantly Related to Hypocalcemia and Severe Inflammation

Xu Qi et al.

Summary: This study aimed to analyze the clinical characteristics and laboratory results of patients with mild and severe COVID-19 infections, finding that severe cases were older, had lower serum calcium ion levels, abnormal blood coagulation, elevated inflammatory factors, and increased calcitonin/procalcitonin levels.

FRONTIERS IN MEDICINE (2021)

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Article Public, Environmental & Occupational Health

Hematological and serum biochemistry parameters as a prognostic indicator of severally ill versus mild Covid-19 patients: A study from tertiary hospital in North India

Deval B. Dubey et al.

Summary: The study showed that hematological and serum biochemistry parameters are important for evaluating the clinical condition and prognosis of COVID-19 patients, which can help clinicians stratify and triage patients upon admission.

CLINICAL EPIDEMIOLOGY AND GLOBAL HEALTH (2021)

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Review Endocrinology & Metabolism

Hypocalcemia is associated with severe COVID-19: A systematic review and meta-analysis

Januar Wibawa Martha et al.

Summary: The meta-analysis showed that hypocalcemia in COVID-19 patients is associated with poor outcomes, with a higher post-test probability in patients with hypocalcemia compared to those without.

DIABETES & METABOLIC SYNDROME-CLINICAL RESEARCH & REVIEWS (2021)

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Letter Endocrinology & Metabolism

Hypocalcemia is a distinctive biochemical feature of hospitalized COVID-19 patients

Luigi di Filippo et al.

ENDOCRINE (2021)

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Article Medicine, General & Internal

Risk factors related to the severity of COVID-19 in Wuhan

Chen Zhao et al.

Summary: This study evaluated characteristics of patients with moderate COVID-19 at admission and identified risk factors associated with disease severity for prognostic prediction. By utilizing machine learning algorithms, features such as interleukin-6 and high-sensitivity cardiac troponin I were found to contribute significantly to predicting disease severity.

INTERNATIONAL JOURNAL OF MEDICAL SCIENCES (2021)

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Article Medicine, General & Internal