4.6 Article

A New Classification of the Severity of Psoriasis: What's Moderate Psoriasis?

Journal

LIFE-BASEL
Volume 11, Issue 7, Pages -

Publisher

MDPI
DOI: 10.3390/life11070627

Keywords

psoriasis; severity; classification; moderate; discrimination; cut-offs

Funding

  1. Celgene

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This study proposes a ranking system for assessing the severity of psoriasis, classifying patients into three categories: mild, moderate, and severe based on different disease measures.
The purpose of this study is to propose a ranking system for the severity of psoriasis. The consensus method of selecting the indices to include and the classification of real patient profiles by an expert panel to create a gold standard of severity were used. The performance of potential cut-offs was evaluated to create a ranking algorithm. The combined use of PASI, BSA, and sPGA may allow the classification of the severity of psoriatic patients. The final algorithm identifies severe patients in a single step (2 out 3 are met: PASI >= 11 or BSA >= 10 or sPGA >= 3), while two steps are required for mild ((2 out 3 are met: PASI <= 3 or BSA <= 5 or sPGA <= 2) and DLQI < 5) and moderate forms (the patient does not meet 2 out 3 (PASI >= 11 or BSA >= 10 or sPGA >= 3) but has a DLQI >= 5. A ranking algorithm is presented, consisting of different measures of disease which classifies psoriatic patients into three categories: mild, moderate, and severe.

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