4.6 Review

Role of Matrix Gla Protein in the Complex Network of Coronary Artery Disease: A Comprehensive Review

Related references

Note: Only part of the references are listed.
Article Hematology

Off-target effects of oral anticoagulants - vascular effects of vitamin K antagonist and non-vitamin K antagonist oral anticoagulant dabigatran etexilate

Rick H. van Gorp et al.

Summary: Short-term treatment with warfarin promotes the formation of atherosclerotic plaques, while long-term use increases calcification activity in plaques. Dabigatran significantly reduces plaque progression compared to warfarin. Warfarin and thrombin increase VSMC oxidative stress and extracellular vesicle release, which can be prevented by dabigatran.

JOURNAL OF THROMBOSIS AND HAEMOSTASIS (2021)

Article Biochemistry & Molecular Biology

Circulating Levels of Dephosphorylated-Uncarboxylated Matrix Gla Protein in Patients with Acute Coronary Syndrome

Admira Bilalic et al.

Summary: The study found that dp-ucMGP levels were significantly higher in NSTEMI patients compared to STEMI patients. NSTEMI status and positive family history of cardiovascular diseases were independent predictors of the highest tertile of dp-ucMGP levels. Among NSTEMI patients, those at high risk of in-hospital mortality had significantly higher dp-ucMGP levels, suggesting it could aid in identifying high-risk NSTEMI patients.

MOLECULES (2021)

Review Medicine, General & Internal

Coronary Artery Calcium: Where Do We Stand After Over 3 Decades?

Scott M. Grundy et al.

Summary: The use of coronary artery calcium scanning can guide statin therapy in patients at intermediate risk, with treatment being delayed for those with <5% 10-year risk. Exceptions include patients with severe hypercholesterolemia, diabetes, or a strong family history of atherosclerotic disease. Depending on the Agatston units of coronary calcium, statin therapy can be determined, with risk factor analysis combined with calcium scanning offering the most evidence-based approach.

AMERICAN JOURNAL OF MEDICINE (2021)

Article Cardiac & Cardiovascular Systems

The Use of Subclinical Atherosclerosis Imaging to Guide Preventive Cardiology Management

Meshal Soni et al.

Current Cardiology Reports (2021)

Review Biochemistry & Molecular Biology

Vascular Calcification in Chronic Kidney Disease: Diversity in the Vessel Wall

Prabhatchandra Dube et al.

Summary: Vascular calcification (VC) is a major cause of cardiovascular morbidity and mortality in patients with chronic kidney disease (CKD), resembling bone metabolism and driven by factors such as hyperphosphatemia and Ca/Pi imbalance. The process involves various cell types and signaling pathways. In-depth analysis of VC types, therapies, and cellular mechanisms aims to aid in the development of preventive, diagnostic, and therapeutic strategies for CKD patients burdened with this disease.

BIOMEDICINES (2021)

Review Cardiac & Cardiovascular Systems

Utilizing coronary artery calcium to guide statin use

Ilana Golub et al.

Summary: CAC is an important factor in determining ASCVD risk, guiding preventive treatments and potentially reducing the number needed to treat for one major cardiac event. The use of CAC in clinical settings and preventative therapy applications may provide cost-effective advantages and improve patient adherence.

ATHEROSCLEROSIS (2021)

Review Biochemistry & Molecular Biology

Vascular Calcification-New Insights into Its Mechanism

Sun Joo Lee et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)

Article Gastroenterology & Hepatology

Inactive matrix Gla protein is elevated in patients with inflammatory bowel disease

Darko Brnic et al.

WORLD JOURNAL OF GASTROENTEROLOGY (2020)

Review Biochemistry & Molecular Biology

The Role of Natural Killer (NK) Cells in Acute Coronary Syndrome: A Comprehensive Review

Marko Kumric et al.

BIOMOLECULES (2020)

Review Radiology, Nuclear Medicine & Medical Imaging

Coronary Artery Calcium Scoring: New Insights into Clinical Interpretation-Lessons from the CAC Consortium

Siegfried Adelhoefer et al.

RADIOLOGY-CARDIOTHORACIC IMAGING (2020)

Article Biochemistry & Molecular Biology

HIF-1α/PDK4/autophagy pathway protects against advanced glycation end-products induced vascular smooth muscle cell calcification

Rui Yang et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2019)

Review Biochemistry & Molecular Biology

The Vicious Cycle of Arterial Stiffness and Arterial Media Calcification

Geoffrey Van den Bergh et al.

TRENDS IN MOLECULAR MEDICINE (2019)

Article Peripheral Vascular Disease

Circulating Dephospho-Uncarboxylated Matrix G a-Protein Is Associated With Kidney Dysfunction and Arterial Stiffness

Houry Puzantian et al.

AMERICAN JOURNAL OF HYPERTENSION (2018)

Article Biochemistry & Molecular Biology

BMP2/Smad signaling pathway is involved in the inhibition function of fibroblast growth factor 21 on vascular calcification

Xiaoxiao Liu et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2018)

Article Cardiac & Cardiovascular Systems

Warfarin, but not rivaroxaban, promotes the calcification of the aortic valve in ApoE-/- mice

Marcello Rattazzi et al.

CARDIOVASCULAR THERAPEUTICS (2018)

Article Surgery

Mechanisms of Arterial Calcification: The Role of Matrix Vesicles

Luca Zazzeroni et al.

EUROPEAN JOURNAL OF VASCULAR AND ENDOVASCULAR SURGERY (2018)

Article Peripheral Vascular Disease

Ten-year changes in ambulatory blood pressure: The prognostic value of ambulatory pulse pressure

Paolo Balietti et al.

JOURNAL OF CLINICAL HYPERTENSION (2018)

Review Nutrition & Dietetics

Is Matrix Gla Protein Associated with Vascular Calcification? A Systematic Review

Hilary Barrett et al.

NUTRIENTS (2018)

Article Hematology

Inhibition of Vascular Calcification: A New Antiatherogenic Mechanism of Topo II (DNA Topoisomerase II) Inhibitors

Lipei Liu et al.

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2018)

Article Ophthalmology

A Naturally Fluorescent Mgp Transgenic Mouse for Angiogenesis and Glaucoma Longitudinal Studies

Priyadarsini Asokan et al.

INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2018)

Review Cardiac & Cardiovascular Systems

Initiation and Propagation of Vascular Calcification Is Regulated by a Concert of Platelet- and Smooth Muscle Cell-Derived Extracellular Vesicles

Leon J. Schurgers et al.

FRONTIERS IN CARDIOVASCULAR MEDICINE (2018)

Article Cardiac & Cardiovascular Systems

Matrix Gla Protein, Plaque Stability, and Cardiovascular Events in Patients with Severe Atherosclerotic Disease

Sabine R. Zwakenberg et al.

CARDIOLOGY (2018)

Article Nutrition & Dietetics

Prevalence and Effects of Functional Vitamin K Insufficiency: The PREVEND Study

Ineke J. Riphagen et al.

NUTRIENTS (2017)

Article Medicine, General & Internal

Vitamin K Dependent Protection of Renal Function in Multi-ethnic Population Studies

Fang-Fei Wei et al.

EBIOMEDICINE (2016)

Article Cardiac & Cardiovascular Systems

Usefulness of Regional Distribution of Coronary Artery Calcium to Improve the Prediction of All-Cause Mortality

Rajesh Tota-Maharaj et al.

AMERICAN JOURNAL OF CARDIOLOGY (2015)

Article Urology & Nephrology

Vitamin K Status and Mortality After Kidney Transplantation: A Cohort Study

Charlotte A. Keyzer et al.

AMERICAN JOURNAL OF KIDNEY DISEASES (2015)

Article Cardiac & Cardiovascular Systems

Vascular calcification: Mechanisms of vascular smooth muscle cell calcification

Jane A. Leopold

TRENDS IN CARDIOVASCULAR MEDICINE (2015)

Article Cardiac & Cardiovascular Systems

A 15-Year Warranty Period for Asymptomatic Individuals Without Coronary Artery Calcium A Prospective Follow-Up of 9,715 Individuals

Valentina Valenti et al.

JACC-CARDIOVASCULAR IMAGING (2015)

Article Multidisciplinary Sciences

Pyruvate Dehydrogenase Kinase 4 Promotes Vascular Calcification via SMAD1/5/8 Phosphorylation

Sun Joo Lee et al.

SCIENTIFIC REPORTS (2015)

Article Hematology

Cross-Sectional Relations of Arterial Stiffness, Pressure Pulsatility, Wave Reflection, and Arterial Calcification

Connie W. Tsao et al.

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2014)

Editorial Material Cardiac & Cardiovascular Systems

New insights for matrix Gla protein, vascular calcification and cardiovascular risk and outcome

Cristina Vassalle et al.

ATHEROSCLEROSIS (2014)

Review Cardiac & Cardiovascular Systems

Medial vascular calcification revisited: review and perspectives

Peter Lanzer et al.

EUROPEAN HEART JOURNAL (2014)

Article Cardiac & Cardiovascular Systems

Will 18F-Sodium Fluoride PET-CT Imaging Be the Magic Bullet for Identifying Vulnerable Coronary Atherosclerotic Plaques?

Nikhil V. Joshi et al.

CURRENT CARDIOLOGY REPORTS (2014)

Article Endocrinology & Metabolism

Matrix Gla Protein Species and Risk of Cardiovascular Events in Type 2 Diabetic Patients

Geertje W. Dalmeijer et al.

DIABETES CARE (2013)

Review Cardiac & Cardiovascular Systems

Task force on: 'Early markers of atherosclerosis: influence of age and sex'

Marco Matteo Ciccone et al.

JOURNAL OF CARDIOVASCULAR MEDICINE (2013)

Article Biochemistry & Molecular Biology

Circulating matrix Gla protein is associated with coronary artery calcification and vitamin K status in healthy women

Geertje W. Dalmeijer et al.

JOURNAL OF NUTRITIONAL BIOCHEMISTRY (2013)

Article Urology & Nephrology

Fibroblast growth factor 23 is not associated with and does not induce arterial calcification

Julia J. Scialla et al.

KIDNEY INTERNATIONAL (2013)

Review Pathology

Recent Developments in Myofibroblast Biology Paradigms for Connective Tissue Remodeling

Boris Hinz et al.

AMERICAN JOURNAL OF PATHOLOGY (2012)

Article Pathology

Microcalcifications in Early Intimal Lesions of Atherosclerotic Human Coronary Arteries

Ruben B. Roijers et al.

AMERICAN JOURNAL OF PATHOLOGY (2011)

Review Medicine, General & Internal

MECHANISMS OF DISEASE The Hemostatic System as a Modulator of Atherosclerosis

Julian Ilcheff Borissoff et al.

NEW ENGLAND JOURNAL OF MEDICINE (2011)

Article Hematology

Paracrine Osteogenic Signals via Bone Morphogenetic Protein-2 Accelerate the Atherosclerotic Intimal Calcification In Vivo

Yusuke Nakagawa et al.

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2010)

Article Cardiac & Cardiovascular Systems

Inhibition of Bone Morphogenetic Proteins Protects Against Atherosclerosis and Vascular Calcification

Yucheng Yao et al.

CIRCULATION RESEARCH (2010)

Article Urology & Nephrology

The Circulating Inactive Form of Matrix Gla Protein Is a Surrogate Marker for Vascular Calcification in Chronic Kidney Disease: A Preliminary Report

Leon J. Schurgers et al.

CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2010)

Article Pathology

Microcalcifications in atherosclerotic lesion of apolipoprotein E-deficient mouse

Nicola Debernardi et al.

INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY (2010)

Article Hematology

Characterisation and potential diagnostic value of circulating matrix Gla protein (MGP) species

Ellen C. M. Cranenburg et al.

THROMBOSIS AND HAEMOSTASIS (2010)

Review Immunology

Macrophage death and defective inflammation resolution in atherosclerosis

Ira Tabas

NATURE REVIEWS IMMUNOLOGY (2010)

Review Cardiac & Cardiovascular Systems

Osteoprotegerin, vascular calcification and atherosclerosis

Ann Van Campenhout et al.

ATHEROSCLEROSIS (2009)

Article Biochemistry & Molecular Biology

The Osteogenic Transcription Factor Runx2 Regulates Components of the Fibroblast Growth Factor/Proteoglycan Signaling Axis in Osteoblasts

Nadiya M. Teplyuk et al.

JOURNAL OF CELLULAR BIOCHEMISTRY (2009)

Review Cardiac & Cardiovascular Systems

Vascular calcification - Pathobiology of a multifaceted disease

Linda L. Demer et al.

CIRCULATION (2008)

Review Hematology

Osteopontin - A multifunctional molecule regulating chronic inflammation and vascular disease

Marta Scatena et al.

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2007)

Article Multidisciplinary Sciences

A hypothesis for vulnerable plaque rupture due to stress-induced debonding around cellular microcalcifications in thin fibrous caps

Yuliya Vengrenyuk et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)

Article Cardiac & Cardiovascular Systems

Pathology of the vulnerable plaque

R Virmani et al.

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2006)

Review Medicine, General & Internal

Vascular smooth muscle cell phenotypic plasticity and the regulation of vascular calcification

V. P. Iyemere et al.

JOURNAL OF INTERNAL MEDICINE (2006)

Review Cardiac & Cardiovascular Systems

Bone morphogenetic proteins in vascular calcification

KA Hruska et al.

CIRCULATION RESEARCH (2005)

Review Hematology

Mechanisms, pathophysiology, and therapy of arterial stiffness

SJ Zieman et al.

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2005)

Review Cardiac & Cardiovascular Systems

Regulation of vascular calcification - Roles of phosphate and osteopontin

CM Giachelli et al.

CIRCULATION RESEARCH (2005)

Article Urology & Nephrology

Mechanisms of vascular calcification in uremia

CM Giachelli

SEMINARS IN NEPHROLOGY (2004)

Article Cardiac & Cardiovascular Systems

Receptor activator of nuclear factor kappa B ligand and osteoprotegerin regulate aortic valve calcification

JJ Kaden et al.

JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2004)

Article Cardiac & Cardiovascular Systems

Phenotypic modulation of vascular smooth muscle cells during medial arterial calcification: A role for endothelin?

R Essalihi et al.

JOURNAL OF CARDIOVASCULAR PHARMACOLOGY (2004)

Article Cardiac & Cardiovascular Systems

Prognostic value of coronary artery calcium screening in subjects with and without diabetes

P Raggi et al.

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2004)

Article Multidisciplinary Sciences

Calcification in atherosclerosis: Bone biology and chronic inflammation at the arterial crossroads

TM Doherty et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)

Article Biochemistry & Molecular Biology

Structural basis of calcification inhibition by α2-HS glycoprotein/fetuin-A -: Formation of colloidal calciprotein particles

A Heiss et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2003)

Article Hematology

Matrix Gla protein (MGP) and bone morphogenetic protein-2 in aortic calcified lesions of aging rats

A Sweatt et al.

JOURNAL OF THROMBOSIS AND HAEMOSTASIS (2003)

Article Hematology

Warfarin-induced artery calcification is accelerated by growth and vitamin D

PA Price et al.

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2000)