Journal
LIFE-BASEL
Volume 11, Issue 6, Pages -Publisher
MDPI
DOI: 10.3390/life11060561
Keywords
SARS-CoV2; COVID-19; coronavirus; diagnosis; screening; prognosis; PCR; CRISP; immunoglobulin
Categories
Funding
- National Institute for Health Research Manchester Biomedical Research Centre (NIHR Manchester BRC)
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RT-PCR remains the gold standard for COVID-19 diagnosis, but more rapid or affordable testing options have been developed. Antigen testing, while less sensitive than molecular assays, may be preferable for wider screening initiatives. Simple parameters can facilitate prognostication and triage.
While molecular testing with real-time polymerase chain reaction (RT-PCR) remains the gold-standard test for COVID-19 diagnosis and screening, more rapid or affordable molecular and antigen testing options have been developed. More affordable, point-of-care antigen testing, despite being less sensitive compared to molecular assays, might be preferable for wider screening initiatives. Simple laboratory, imaging and clinical parameters could facilitate prognostication and triage. This comprehensive review summarises current evidence on the diagnostic, screening and prognostic tests for COVID-19.
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