Journal
TOXICS
Volume 9, Issue 7, Pages -Publisher
MDPI
DOI: 10.3390/toxics9070157
Keywords
phthalates; health risk; extraction techniques; analytical approaches
Categories
Funding
- FCT-Fundacao para a Ciencia e a Tecnologia [UIDB/00674/2020]
- ARDITI-Agencia Regional para o Desenvolvimento da Investigacao Tecnologia e Inovacao [M1420-01-0145-FEDER-000005]
- Fundacao para a Ciencia e Tecnologia
- Madeira 14-2020 program to the Portuguese Mass Spectrometry Network through PROE-QUI-PRAM program [M14-20 M1420-01-0145-FEDER-000008]
- Ministerio de Ciencia, Innovacion y Universidades [RTI2018-099668-BC22]
- Junta de Andalucia [UMA18-FEDERJA-126]
- FEDER funds
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Phthalates, commonly used chemicals in various industrial products, pose potential health risks due to their widespread presence in food items that most people consume on a daily basis. Scientists are developing reliable analytical methods to detect and quantify trace levels of phthalates in food products for health safety concerns.
Phthalates are a group of chemicals used in a multitude of important industrial products (e.g., medical devices, children's toys, and food packages), mainly as plasticizers to improve mechanical properties such as flexibility, transparency, durability, and longevity of polyvinyl chloride (PVC). The wide occurrence of phthalates in many consumer products, including foods (e.g., bottled water, soft drinks, wine, milk, and meat) brings that most people are exposed to phthalates every day, which raises some concerns. Adverse health outcomes from phthalates exposure have been associated with endocrine disruption, deformities in the human reproductive system, increased risk of preterm birth, carcinogen exposure, among others. Apprehension related to the health risks and ubiquitous incidence of phthalates in foods inspires the development of reliable analytical approaches that allow their detection and quantification at trace levels. The purpose of the current review is to provide information related to the presence of phthalates in the food chain, highlighting the health risks associated with their exposure. Moreover, an overview of emerging extraction procedures and high-resolution analytical approaches for a comprehensive quantification of phthalates is presented.
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