Journal
GREEN CHEMISTRY
Volume 18, Issue 4, Pages 1032-1037Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c5gc01838b
Keywords
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Funding
- National Natural Science Foundation of China [21102142, 41322037, 41130858]
- Program of Natural Science Foundation of Shandong Province of China [JQ201510]
- Talents of High Level Scientific Research Foundation of Qingdao Agricultural University [6631112323, 6631115015]
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A green and efficient dehydrative S(N)1-type reaction of indolyl alcohols with diverse nucleophiles was developed using water as the solvent, affording versatile 3-indolyl derivatives in high yields. The advantages of being catalyst-free, environmentally benign, and having a wide substrate scope and easy workup make it a promising method for preparation of indolyl compounds.
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