4.8 Article

Acylation of indoles via photoredox catalysis: a route to 3-acylindoles

Journal

GREEN CHEMISTRY
Volume 18, Issue 5, Pages 1201-1205

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c5gc01931a

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Funding

  1. Program for Innovative Research Team (in Science and Technology) in University of Yunnan Province (IRTSTYN)
  2. State Ethnic Affairs Commission [12YNZ05]

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A visible-light-induced synthesis of 3-acylindoles from simple indoles and alpha-oxo acids at room temperature has been discovered. The reaction tolerates a wide range of functional groups and gives a variety of valuable 3-acylindoles in moderate to high yields under mild conditions.

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