4.7 Article

Dry Gongronema latifolium aqueous extract mediated silver nanoparticles by one-step in-situ biosynthesis for antibacterial activities

Journal

SURFACES AND INTERFACES
Volume 24, Issue -, Pages -

Publisher

ELSEVIER
DOI: 10.1016/j.surfin.2021.101116

Keywords

Silver nanoparticles; Gongronema latifolium; biosynthesis; antibacterial activities

Funding

  1. NCP-TWAS Postdoc Fellowship award [NCP-CAAD/TWAS_Fellow8408]
  2. TETFUND [TETF/DESS/UNN/NSUKKA/STI/VOL.I/B4.33]
  3. [VRSP/UNISA/90407830]

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In this study, silver nanoparticles doped with aqueous extract of dry Gongronema Latifolium (DGL) were successfully synthesized in-situ, showing significant functional susceptibility against bacterial strains, especially surpassing gentamicin for certain strains. The formulated DGL-AgNPs exhibit strong bactericidal properties with facile, benign, eco-friendly, biocompatible, and innocuous synthesis procedures.
In-situ biosynthesis of silver nanoparticles for antibacterial activities doped with aqueous extract of dry Gongronema Latifolium (DGL) is presented in this work. The absorbance was determined using a UV-Visible analysis with a peak of 428 nm. The obtained particles confirmed by the TEM image analysis were spherical in shape with an average particle size between 5 and 20 nm. A single crystalline phase of FCC was confirmed by the powder. The functional groups showed the phytochemical inherent in the sample. The colloidal solution of DGL-AgNPs with MIC of 10 mu g/ml showed a noteworthy functional susceptibility against the bacterial strains, particularly, K. pneumonia with susceptibility greater than gentamicin. Based on these observations, the formulated DGL-AgNPs show strong bactericidal against the pathogens with facile, benign, eco-friendly, biocompatibility and innocuous synthesis procedures. This can serve as an efficient bactericidal agent.

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