Side Effects of mRNA-Based and Viral Vector-Based COVID-19 Vaccines among German Healthcare Workers

Summary: The study found that detecting fake news and health literacy scores are associated with the intention to get vaccinated against SARS-CoV-2. Poor detection of fake news and health literacy scores increase individuals' likelihood of being hesitant or anti-vaccination.

JOURNAL OF PUBLIC HEALTH (2021)

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Letter Dermatology

Oral candidiasis of COVID-19 patients: Case report and review of evidence

Abanoub Riad et al.

JOURNAL OF COSMETIC DERMATOLOGY (2021)

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Editorial Material Medicine, General & Internal

Why did a German newspaper insist the Oxford AstraZeneca vaccine was inefficacious for older people-without evidence?

Hristio Boytchev

BMJ-BRITISH MEDICAL JOURNAL (2021)

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Review Medicine, General & Internal

Oral Complications of ICU Patients with COVID-19: Case-Series and Review of Two Hundred Ten Cases

Barbora Hockova et al.

Summary: This study evaluated the prevalence and characteristics of oral complications in critically ill COVID-19 patients, revealing a variety of issues such as haemorrhagic ulcers and necrotic ulcers. Prolonged prone positioning and mechanical ventilation devices were identified as primary risk factors for these complications, emphasizing the importance of a multidisciplinary approach for patient monitoring and management.

JOURNAL OF CLINICAL MEDICINE (2021)

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Review Immunology

SARS-CoV-2 mRNA Vaccines: Immunological Mechanism and Beyond

Emily Bettini et al.

Summary: To successfully protect against pathogen infection, a vaccine must trigger efficient adaptive immunity involving B and T cell responses. mRNA vaccines have become leaders in the race to develop an effective COVID-19 vaccine due to their rapid development capabilities and ability to induce robust adaptive immune responses.

VACCINES (2021)

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Letter Allergy

Polyethylene glycol (PEG) is a cause of anaphylaxis to the Pfizer/BioNTech mRNA COVID-19 vaccine

Priya Sellaturay et al.

CLINICAL AND EXPERIMENTAL ALLERGY (2021)

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Article Virology

Non-life-threatening adverse effects with COVID-19 mRNA-1273 vaccine: A randomized, cross-sectional study on healthcare workers with detailed self-reported symptoms

Renuka Ananth Kalyan Kadali et al.

Summary: A study investigated the side effects of the mRNA-1273 vaccine among healthcare workers, finding that most recipients experienced one or more symptoms post-vaccination, but the majority were able to continue their daily activities unaffected. Despite a wide range of reported symptoms, the vast majority of healthcare workers did not plan to skip the second dose of the vaccine, indicating high acceptance for the vaccine.

JOURNAL OF MEDICAL VIROLOGY (2021)

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Letter Dermatology

Improving cultural competency and practicing cultural humility in dermatologic training: Skin of color education and board certification

Trisha Kaundinya et al.

JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY (2021)

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Article Infectious Diseases

Vaccine side-effects and SARS-CoV-2 infection after vaccination in users of the COVID Symptom Study app in the UK: a prospective observational study

Cristina Menni et al.

Summary: This study investigated the safety and effectiveness of the BNT162b2 and ChAdOx1 nCoV-19 vaccines in a UK community setting. The results showed that the frequencies of side effects from these vaccines were lower than reported in clinical trials, and a significant reduction in the risk of SARS-CoV-2 infection was observed starting at 12 days after vaccination.

LANCET INFECTIOUS DISEASES (2021)

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Article Environmental Sciences

Facial and Oral Manifestations Following COVID-19 Vaccination: A Survey-Based Study and a First Perspective

Marta Mazur et al.

Summary: The study found that the majority of people vaccinated with BNT162b2 and mRNA-1273 vaccines did not experience oral and facial symptoms. Therefore, there is no significant correlation between COVID-19 vaccination and facial and oral manifestations based on this preliminary survey.

INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH (2021)

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Article Medicine, General & Internal

Prevalence of COVID-19 Vaccine Side Effects among Healthcare Workers in the Czech Republic

Abanoub Riad et al.

Summary: The study conducted a survey on the side effects of the Pfizer-BioNTech COVID-19 vaccine among healthcare workers in the Czech Republic, revealing common side effects such as injection site pain, fatigue, and headache. Younger age groups and individuals who received two doses of the vaccine were more likely to experience side effects, with the overall prevalence of side effects higher than reported by the manufacturer.

JOURNAL OF CLINICAL MEDICINE (2021)

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Article Immunology

Acceptance of COVID-19 Vaccination among Front-Line Health Care Workers: A Nationwide Survey of Emergency Medical Services Personnel from Germany

Andre Nohl et al.

Summary: The study aimed to assess the COVID-19 vaccination acceptance of EMS personnel as front-line health care workers in Germany. Results showed a majority willingness to be vaccinated, with some participants still undecided. The study recommends interventions such as continuing education and awareness campaigns to increase vaccine acceptance among hesitant groups.

VACCINES (2021)

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Article Biology

Self-Reported Real-World Safety and Reactogenicity of COVID-19 Vaccines: A Vaccine Recipient Survey

Alexander G. Mathioudakis et al.

Summary: The study compares the safety, tolerability, and reactogenicity of different COVID-19 vaccines among various recipient groups. Those who had a prior COVID-19 infection were found to have an increased risk of vaccination side effects, with mRNA vaccines causing milder systemic reactions but more local reactions compared to viral vector-based vaccines.

LIFE-BASEL (2021)

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Article Medicine, General & Internal

Minor to Moderate Side Effects of Pfizer-BioNTech COVID-19 Vaccine Among Saudi Residents: A Retrospective Cross-Sectional Study

Nagla A. El-Shitany et al.

Summary: This study tracked the short-term side effects of the Pfizer vaccine, finding common symptoms to include injection site pain, headaches, and fever. Females and individuals previously infected with the coronavirus were more likely to experience side effects.

INTERNATIONAL JOURNAL OF GENERAL MEDICINE (2021)

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Article Medicine, General & Internal

Prevalence and Risk Factors of CoronaVac Side Effects: An Independent Cross-Sectional Study among Healthcare Workers in Turkey

Abanoub Riad et al.

Summary: COVID-19 vaccine hesitancy poses a serious threat to achieving community immunity through mass vaccination. Independent studies on vaccine side effects can help boost public confidence and uptake. A study in Turkish healthcare workers found a higher prevalence of CoronaVac side effects compared to clinical trials, with factors like gender and health status potentially impacting the risk of side effects.

JOURNAL OF CLINICAL MEDICINE (2021)

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Article Immunology

Side Effects Reported by Jordanian Healthcare Workers Who Received COVID-19 Vaccines

Osama Abu-Hammad et al.

Summary: The survey conducted among healthcare professionals who received COVID-19 vaccines in Jordan showed that around 18% and 31% reported no side effects after the first and second doses respectively. Most of the side effects were local, while systemic side effects like fatigue, myalgia, headache, and fever were more common after the first dose, particularly associated with the AstraZeneca vaccine and age <= 45 years. No serious side effects were reported, indicating that the side effects of COVID-19 vaccines in Jordan are similar to what have been known before. Further studies with larger sample sizes and longer follow-up periods are needed to monitor potential serious and long-term side effects.

VACCINES (2021)

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Article Immunology

Evaluation of Side Effects Associated with COVID-19 Vaccines in Saudi Arabia

Abdulaziz Alhazmi et al.

Summary: A study conducted in Saudi Arabia found that side effects reported after receiving Oxford-AstraZeneca and Pfizer-BioNTech vaccines are similar to those reported in clinical trials, indicating the safety of these vaccines. Most participants reported fatigue and pain at the injection site as common side effects. Further research is needed to assess the effectiveness of these vaccines in protecting against SARS-CoV-2 reinfections.

VACCINES (2021)

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Article Immunology

Safety of ChAdOx1 nCoV-19 Vaccine: Independent Evidence from Two EU States

Abanoub Riad et al.

Summary: This study investigated the prevalence of side effects following AstraZeneca COVID-19 vaccine among healthcare workers in Germany and Czech Republic. The majority of participants reported experiencing at least one side effect, with common symptoms including injection site pain, fatigue, and muscle pain. Most side effects resolved within 1-3 days, with younger age groups being less affected and slightly higher frequencies observed in females and participants previously infected with COVID-19. Further independent studies are needed to evaluate vaccine safety and explore potential factors influencing side effects.

VACCINES (2021)

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Letter Dentistry, Oral Surgery & Medicine