4.8 Article

Highly stereoselective and catalyst-free synthesis of annulated tetrahydropyridines by intramolecular imino-Diels-Alder reaction under microwave irradiation in water

Journal

GREEN CHEMISTRY
Volume 18, Issue 13, Pages 3712-3717

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c6gc00912c

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Funding

  1. CONICYT [821320027]

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A microwave-assisted method for the synthesis of tetracyclic tetra-hydropyridines via an intramolecular imino-Diels-Alder reaction in water is reported. The reaction proceeds under catalyst-free conditions and shows excellent stereoselectivity.

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